Cases reported "Tracheal Diseases"

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1/41. Wegener's granulomatosis causing laryngeal and tracheobronchial obstruction in an adolescent girl.

    A 12-year-old girl presenting with a painful neck mass and ulcerated gingival lesions was found to have Wegener's granulomatosis involving the gingivae, paranasal sinuses, ears, mastoids, larynx, trachea, bronchial tree, lungs, kidneys and joints. The initial illness and two subsequent exacerbations were treated with intravenous and oral cyclophosphamide and prednisone. Secondary infections have been managed with establishment of good drainage and use of appropriate antibiotics. The patient is well with a normal sedimentation rate 4 1/2 years after the onset of her disease.
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2/41. Congenital tracheobiliary fistula.

    Congenital respiratory tract-biliary fistula, including tracheo- and broncho-biliary fistulae, are rare developmental anomalies. To date, only 18 cases have been reported. We present two additional cases that came to our attention after a long and difficult attempt to make a diagnosis. After surgical excision of the tract both children have remained symptom-free for 6 and 4 years, respectively. bronchoscopy allows an early diagnosis, but patients also have to be investigated for associated biliary tree malformations.
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3/41. Otolaryngologic manifestations of Rosai-Dorfman disease.

    PURPOSE: To describe an unusual head and neck occurrence of Rosai-Dorfman disease (RDD) and to review the otolaryngologic manifestations of this rare entity. methods: A case presentation with review of the literature describing Rosai-Dorfman disease and its head and neck involvement. Setting: A tertiary care, urban children's hospital. RESULTS: This is the first description, to the best of our knowledge, of RDD [Sinus histiocytosis with Massive Lymphadenopathy (SHML)] involving bilateral external auditory canals and middle ear in a 12 year old patient previously diagnosed with 'asthma' and hearing loss. This patient also had extensive involvement of the tracheobronchial tree. Representative clinical, radiographic and histological findings are presented. Its etiology, diagnosis and management are also reviewed. CONCLUSION: This is the first reported case of middle ear and external auditory canal involvement of RDD in a patient with hearing loss and associated tracheobronchial lesions. RDD, although rare, may be considered in the differential diagnosis of unusual histiocytic lesions of the external auditory canal, especially with findings of similar or comparable lesions involving the respiratory tract. Confirmation is with identification of emperipolesis and appropriate immunohistochemical staining (S-100 positive, CD-68 positive and CD-1a negative). Intervention is recommended in cases where there is increased risk of mortality, as in severe obstruction of the tracheobronchial tree. Otherwise, since these lesions are self-limiting, the patients can be observed closely.
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4/41. External-beam radiation therapy in the treatment of diffuse tracheobronchial amyloidosis.

    Tracheobronchial amyloidosis is characterized by deposits of amyloid in airway walls. No effective treatment is known. We describe a 59-year-old woman who presented with increasing symptoms of airway obstruction due to diffuse deposition of amyloid throughout her tracheobronchial tree. She was treated with external-beam radiation therapy (20 Gy) with marked improvement in her symptoms, effort tolerance, bronchoscopic appearance, and forced expiratory volume in 1 second (1.39 L to 1.97 L [42%]). This improvement was maintained during 21 months of follow-up.
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5/41. Tracheobronchopathia osteochondroplastica: report of three cases.

    Tracheobronchopathia osteochondroplastica (TO) is a rare disease characterized by the presence of osseous and cartilaginous submucosal nodules in the tracheobronchial tree. The majority of patients remain asymptomatic; however, a small number develop severe airway stenosis. Symptoms may include dyspnea, hoarseness, cough, hemoptysis, and recurrent pneumonia. Plain chest X-ray films are often unremarkable but may demonstrate atelectasis, consolidation, tracheal nodularity, or narrowing. CT reveals tracheal nodularity with calcification and narrowing. This article reviews the cross-sectional imaging characteristics of TO.
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6/41. trachea stabilisation with autologous costal cartilage in acquired tracheomalacia: report of two cases.

    Post-operative tracheomalacia is a life threatening condition whose management is challenging. Surgical procedures which have been suggested in the literature to manage the condition include tracheostomy, staged thyroid reductions and the use of artificial stents either within the lumen of the tracheobronchial tree or as external support. We report the successful management of two patients using autologous costal cartilage to support the tracheal wall.
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7/41. warfarin-induced tracheobronchial calcification.

    Calcification of the trachea and proximal bronchi is a common, normal finding on chest radiographs in the elderly population, especially in women. More extensive airway calcification is also a rare manifestation of many pathologic conditions. The authors report a case of pathologic tracheobronchial calcification associated with long-term warfarin therapy. Chest radiographs showed prominent, diffuse calcification of the tracheobronchial tree. Computed tomography showed extensive calcification of the airway walls, extending from the trachea to the lung periphery.
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8/41. Obstruction of upper airways complicating tracheostomy and use of neodymium Yag laser.

    Mucoid impaction of tracheobronchial tree is a common condition which may complicate tracheostomy. Here we describe a case of a 72-year-old man, status after tracheostomy, who presented to the hospital with an acute upper airways obstruction and respiratory arrest due to a tracheal cast. The cast was successfully dislodged by the Nd-Yag laser.
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9/41. Tracheobronchial obstruction due to silicosis.

    Broncholithiasis can result in airway obstruction through the erosion of calcified lymph nodes into the bronchial lumen or by extrinsic compression of the tracheobronchial tree. We report an unusual case of broncholithiasis in a patient with silicosis who developed airway obstruction from endobronchial polypoid masses of granulation tissue adjacent to calcified mediastinal lymph nodes. The production of granulation tissue may have been the result of broncholiths in the early stages of erosion into the tracheobronchial tree. Efforts to ablate the endobronchial polyps using YAG laser phototherapy were only temporarily successful and surgical removal of the calcified mediastinal lymph nodes was required to halt further polyp growth. Surgical specimens grew mycobacterium avium-intracellulare (MAI), a common pathogen in patients with silicosis. MAI may have contributed to the local inflammatory milieu provoking the exuberant tissue response.
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10/41. Invasive tracheobronchial aspergillosis in an immunocompetent person.

    Tracheobronchial involvement is an uncommon form of invasive pulmonary aspergillosis and is found mainly in immunocompromised individuals such as patients with leukemia and prolonged granulocytopenia due to cytotoxic therapy, organ transplant recipients receiving high-dose corticosteroids, or patients with chronic granulomatous diseases. Rarely, such a pattern can also be seen in immunocompetent persons or can involve atypical sites such as the paranasal sinuses, skin, and the tracheobronchial tree. Occasionally, these patients require a prolonged course of antifungal agents. We report a case of aspergillosis involving the tracheobronchial tree in an immunocompetent young male that presented a diagnostic dilemma.
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