1/23. The amyloid deposit in calcifying epithelial odontogenic tumor is immunoreactive for cytokeratins.Calcifying epithelial odontogenic tumor, also known as Pindborg tumor, is a rare benign tumor with locally aggressive behavior. It is characterized by squamous epithelial cells, calcifications, and eosinophilic deposits that have been identified as amyloid. We report a case of calcifying epithelial odontogenic tumor and investigate the nature of the amyloid, using histologic, immunohistochemical, and ultrastructural studies. The amyloid was immunohistochemically negative for basement membrane components and positive for all cytokeratin stains performed (cocktail of cytokeratins 1, 5, 6, 8, 13, and 16, and cytokeratins AE1 and AE3). The amyloid stained focally in a glandular-like pattern, reminiscent of the epithelial glandlike structures of the tumor. We conclude that the amyloid is derived from filamentous degeneration of keratin filaments that originate from the tumor squamous epithelium. The keratin degeneration is part of a developmental or aging process that the tumor undergoes.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
2/23. Polymorphous low-grade adenocarcinoma of the oral cavity.Polymorphous low-grade adenocarcinoma (PLGA) is a neoplasm arising most commonly within the minor salivary glands of the oral cavity. Not recognized as a distinct entity until 1983, PLGA was often misdiagnosed as adenoid cystic carcinoma or pleomorphic adenoma. PLGA is thought to be the second most common salivary gland tumor after mucoepidermoid carcinoma. Affecting individuals later in life, PLGA often presents as a firm, painless nodule that exhibits a locally aggressive, infiltrative pattern. Because of PLGA's slow growth rate and low rate of metastasis, differentiation from other disease entities is crucial for treatment modalities. The study presented here reviews three cases of PLGA, their treatment and follow-up.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
3/23. Acinic cell carcinoma of the oral cavity.A rare case of acinic cell carcinoma of minor salivary gland origin within the oral cavity is reported in a 62-year-old woman. These tumors most commonly arise in the parotid gland and follow an insidious course requiring long-term follow-up. The gross and histologic features of the patient's tumor include pseudoencapsulation, mixed solid and acinar architecture, microcyst formation, and the presence of conspicuous diastase-fast and PAS-positive cytoplasmic granules, characteristic of lesions that have been called acinic cell carcinoma by a variety of authors. Surgical excision is the treatment of choice. However, following an incisional biopsy, the patient refused further surgical treatment and has remained clinically disease-free three years postoperatively.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
4/23. Repair of an intrabony defect from an adenomatoid odontogenic tumor.This case report describes the occurrence and treatment of an adenomatoid odontogenic tumor (AOT) presenting as a periodontal intrabony defect on a upper lateral incisor. Following incision and flap reflection, a solid, rubbery specimen was enucleated in one piece leaving a wide moat-like intrabony defect. A bioabsorbable membrane of glycolide and lactide copolymer was sutured over the defect to maximize regeneration and the flaps then sutured over the membrane. Microscopic analysis of the biopsied specimen revealed dental hard tissue interspersed in a field of odontogenic epithelium in a glandular configuration, consistent with a diagnosis of AOT. AOT is a rare odontogenic tumor usually associated with unerupted teeth or dentigerous cysts, not periodontal defects. Clinical evaluation 6 months postoperatively revealed restoration of clinical attachment and periodontal health.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
5/23. Myxomatous odontogenic tumor of the maxilla. An unusual case with squamous and mucoproducing epithelial component.A tumor attached to the amelo-cemental junction of a third molar impacted in the maxillary tuberosity, consisted histologically of a myxomatous stroma, in which multicystic cavities lined by a columnar epithelium and mucoproducing cells, together with an aggressive squamous epithelial component were present. Although the diagnosis of polyp of the maxillary sinus cannot be excluded, this lesion most likely constitutes an unusual presentation for an odontogenic myxoma of the maxilla, in which an aggressive squamous epithelial component is present, along with a mucosecreting glandular component.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
6/23. Intraosseous pleomorphic adenoma: case report and review of the literature.Pleomorphic adenoma is the most common neoplasm of the salivary glands, affecting mainly the parotid gland. The preferential intraoral site of this tumor is the palate. A case of a 31-year-old woman with an intraosseous pleomorphic adenoma located in the maxilla (left paramedian region), showing an approximate evolution of one year is reported. The present intraosseous case represents a rare location, with the tumor probably originating from glandular epithelial remnants captured during embryogenesis. In a review of the literature of 142 cases of intragnathic localization (24% in the maxilla) are identified. A slight predominance of women was observed (56%), with 55% of the patients being affected during the 5th to 7th decade of life. The tumors were malignant in 94% of the cases, with special predominance of mucoepidermoid carcinoma (65%). Intraosseous pleomorphic adenomas are rare, with the present patient being the 6th case reported in the literature and the second found in the maxilla. Mean age of the 5 previously reported cases was 58.8 years.- - - - - - - - - - ranking = 1.5keywords = gland (Clic here for more details about this article) |
7/23. Maxillary odontogenic myxoma: a diagnostic pitfall on aspiration cytology.A painless, slow-growing cheek swelling in a young male clinically considered a salivary gland mass was aspirated. Cytology smears were hypocellular. The striking feature was abundant myxoid material with a few monomorphic oval cells, interpreted as myxoid variant of pleomorphic adenoma. Subsequent CT scan was suggestive of a malignant tumor but biopsy confirmed it as myxoma. myxoma of the jaw is a rare benign tumor that has a tendency for bone destruction, invasion into surrounding structures, and a relatively high recurrence rate. Maxillary myxoma is less frequent but behaves more aggressively than in the mandible, as it spreads through the maxillary sinus. Cytologically, it should be differentiated from other tumors showing predominant myxoid change. awareness of potential diagnostic pitfalls and careful evaluation of clinical and radiological data is necessary to narrow the differential diagnosis.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
8/23. Mucinous adenocarcinoma of probable minor salivary gland origin.Mucinous adenocarcinoma is characterized by large pools of extracellular mucin. The tumor has been reported in the nasal cavity, paranasal sinus, breast, colon, stomach, prostate, skin, and lung. Mucinous adenocarcinoma also arises as a primary tumor of the major salivary glands. However, its occurrence is exceedingly rare and has only recently been recognized. Only 9 cases in the major salivary glands have been reported. We present an additional case of MAC in the maxilla that was considered to have developed from a palatal minor salivary gland.- - - - - - - - - - ranking = 3.5keywords = gland (Clic here for more details about this article) |
9/23. Genetic profile of clear cell odontogenic carcinoma.In the head and neck region, clear cell tumors are usually derived from salivary glands, odontogenic tissues, and metastasis. The world health organization has classified clear cell odontogenic tumor among benign tumors, but it is now recognized as a more sinister lesion, and current opinion is that it should be designated as a carcinoma. It is characterized by aggressive growth, recurrences, and metastasis. By using complementary dna microarrays, several genes in clear cell odontogenic tumor were identified that are differentially regulated when compared with non-tumor tissue. In conclusion, the first genetic profiling of clear odontogenic carcinoma is reported. dna microarrays can potentially help in identifying some genes whose products could be disease-specific targets for cancer therapy as well as a tool for better classifying odontogenic tumor.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
10/23. Malignant lymphoma of the jaw bone.BACKGROUND: Malignant lymphomas are neoplasms originating from lymphocytes, whose precursor cell or cells are generated during the multipotential differentiation of a stem cell. Extranodal localization most often involves the Waldeyer's ring, nasal cavity, maxillary sinuses, eyeballs, salivary glands, oral cavity, stomach or skin. Localization in the nervous system or facial bones is very rare. CASE REPORT: This article presents a rare case of a patient with B-cell lymphoplasmocytic lymphoma located in the jaw bones. The diagnosis was established after histopathological investigation of periapical lesions. Due to the localized growth of the malignant lymphoma, the patient underwent surgery combined with radiotherapy. The follow-up period amounted to 14 months and the patient now presents without recurrences or lymphadenopathy. CONCLUSIONS: All periapical lesions should be sampled for histopathological examination, possibly revealing a hidden neoplastic process.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
| | Next -> |