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1/6. Oral lichen sclerosus et atrophicus. A case report.

    lichen sclerosus et atrophicus affecting only the oral mucosa is extremely rare. We report here a case of oral lichen sclerosus et atrophicus presenting as a white, flat lesion involving the right buccal and labial mucosa and vermillion border. The diagnosis was based on histopathologic features. Treatment with intralesional corticosteroid was successful in reducing the size of the lesion and the symptoms of the patient. A free gingival graft was also performed to restore the lost attached gingiva. No recurrence of the lesion was found after a 1-year follow-up period, and no skin or genital lesions developed during the 3 years of treatment.
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ranking = 1
keywords = labial
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2/6. Surgicel in the management of labial and clitoral hood adhesions in adolescents with lichen sclerosus.

    STUDY OBJECTIVE: Lichen sclerosus (LS) is an inflammatory dermatosis of the vulva with potentially destructive consequences to the young woman's perineum. Long-term sequelae include atrophy of the labia minora, scarring of the clitoral hood, and labial and/or clitoral hood adhesions. This study aims to find techniques for preventing these devastating effects. PARTICIPANTS: Three young women, ages 14 and 15 years, with a long history of lichen sclerosus and labial adhesions, presented with recurrent labial and periclitoral adhesions. Increasing pain prior to presentation, exquisite enough to inhibit even walking, necessitated urgent operative intervention. Scarring of the clitoral hood with an area of firmness beneath the scarring was present. Sharp dissection of the clitoral hood was performed with the entrapped keratinaceous debris and hair expressed. The adherent labia were separated. Surgicel, oxidized regenerated cellulose gauze (Johnson & Johnson, Arlington, TX), was sutured to the exposed clitoral hood and labial surfaces with vicryl suture. Complete dissolution of the Surgicel occurred between postoperative day 4-6 without recurrence of adhesions. One-year follow-up did not reveal any evidence of recurrence in any of the three patients. CONCLUSION: The recurrence of labial and clitoral hood adhesions in young women with a history of LS was prevented for at least 1 year by surgical lysis and application of Surgicel to the affected area. This technique has prevented the recurrence during the interval when these surfaces are at highest risk of re-agglutination.
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ranking = 9
keywords = labial
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3/6. A case of labial adhesion due to lichen sclerosus et atrophicus.

    A 67-year-old Japanese woman first visited to the hospital in regard to episodes of a 6 months history of difficulty on urination. Her perineum was mild whitish, and labia majorae were all adhered with only a pinhole-sized opening. A labial incision was performed under a spinal anesthesia. Pathological finding of the skin biopsy specimen was lichen sclerosus et atrophicus (LSA). In view of that LSA occasionally develops into squamous cell carcinoma, urologists should be care of LSA in labial adhesion case.
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ranking = 6
keywords = labial
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4/6. lichen sclerosus et atrophicus of the oral mucosa.

    lichen sclerosus et atrophicus (LSA) is a chronic, benign, depigmenting disease of the skin and mucous membranes most frequently affecting the female genitalia. Involvement of the oral mucosa without concurrent genital or skin lesions has been reported only occasionally in the literature. In view of the rarity of reported cases, one lesion affecting only the labial mucocutaneous area is presented along with a description of the disease's clinical and histopathological findings.
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ranking = 1
keywords = labial
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5/6. Lichen sclerosus of the lip.

    Lichen sclerosus is a chronic inflammatory mucocutaneous disorder predominately affecting prepubertal girls and postmenopausal women. Isolated lichen sclerosus affecting the oral mucosa is exceedingly rare. Only 13 patients with biopsy-proved isolated oral disease have been reported in the literature. We report a 10-year-old Caucasian girl with a well-demarcated 1.5 cm x 1.2 cm atrophic white plaque with a violaceous border and focal telangiectases on the right inferior vermillion lip, extending on to the labial mucosa. No other cutaneous surfaces, including genitalia, were involved. Incisional biopsy of the plaque on the lip revealed a patchy lichenoid infiltrate of lymphocytes associated with sclerosis of the papillary dermis and a thinned epidermis consistent with a diagnosis of lichen sclerosus. Treatment with a short course of high potency topical corticosteroids likely prevented the progression of this lesion.
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ranking = 1
keywords = labial
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6/6. lichen sclerosus et atrophicus of the oral cavity: report of two cases.

    lichen sclerosus et atrophicus is a depigmenting mucocutaneous disease most frequently affecting the female genitalia. Genital lesions are symptomatic and may be functionally debilitating. Oral lesions are of little significance other than the esthetic concerns of perioral lesions. In view of the rarity of reported cases, one lesion of the labial mucocutaneous area and a second of the palate are presented along with a description of the disease's clinical and histopathologic findings and a brief review of the literature. The lip lesion was partially resolved with topical corticosteroids and was then fully eliminated with topical testosterone. Histologic verification and examination for the simultaneous occurrence or absence of oral and the more common genital-cutaneous lesions is essential if meaningful information in the medical-dental literature is to be obtained in the future.
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ranking = 1
keywords = labial
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