1/16. Atypical anterior optic neuropathy caused by toxoplasmosis.PURPOSE: To report atypical anterior optic neuropathy due to toxoplasmosis. methods: Interventional case report. A 33-year-old male presented with sudden painless loss of vision and floaters in the right eye. Examination demonstrated a best-corrected visual acuity of 20/200, optic nerve head edema, retinal hemorrhages, and vitreous opacities. RESULTS: Nine days later, a granuloma at the optic nerve head was apparent, and the patient was treated with pyrimethamine, sulfadiazine, folinic acid, and prednisone. Six weeks after initiating therapy, best-corrected visual acuity had improved to 20/25. CONCLUSION: optic nerve involvement in toxoplasmosis is uncommon and, when it occurs, usually presents with a white inflammatory mass on the optic disk. The current case demonstrates the importance of including toxoplasmosis in the differential diagnosis of unilateral anterior optic neuropathy, even if a focal inflammatory mass is not apparent.- - - - - - - - - - ranking = 1keywords = optic, edema (Clic here for more details about this article) |
2/16. Ocular toxoplasmosis presenting as neuroretinitis: report of two cases.BACKGROUND: Neuroretinitis is a clinical entity usually seen in young healthy adults, that is characterized by rapid profound unilateral loss of vision and includes optic nerve head edema, splinter hemorrhages, macular exudate in a stellate pattern, and variable vitreous inflammation. There are numerous entities that can cause a picture of neuroretinitis ranging from vascular to infectious to autoimmune. PATIENT AND methods: We report two patients with neuroretinitis, who presented with unilateral blurred vision and had serologic evidence of toxoplasma gondii infection. RESULTS: Both patients responded well to treatment with systemic antibiotics and corticosteroids. visual acuity returned to 20/60 in one patient and 20/20 in the other. CONCLUSION: Although the etiology is usually idiopathic, infectious causes of neuroretinitis, including toxoplasmosis, should be kept in mind in order to maintain visual acuity by early diagnosis and appropriate therapy.- - - - - - - - - - ranking = 0.11234002606849keywords = optic, edema (Clic here for more details about this article) |
3/16. Presumed ocular toxoplasmosis presenting as papillitis.Unilateral papillitis is a rare manifestation of ocular toxoplasmosis. However, other causes of papillitis need to be ruled out before concluding the diagnosis.- - - - - - - - - - ranking = 430.36178055681keywords = papillitis (Clic here for more details about this article) |
4/16. Third-generation optical coherence tomography findings in punctate retinal toxoplasmosis.PURPOSE: To investigate optical coherence tomography (OCT) findings in patients with punctate retinal toxoplasmosis (PRT). DESIGN: Observational case series. methods: Setting: Tertiary ophthalmic referral center. Study population: Four patients with PRT consecutively evaluated between July 2004 and June 2005. observation Procedures: Clinical examination and OCT. Main Outcome Measures: Morphologic features at baseline and changes within a 24-week follow-up interval. RESULTS: Retinal layers were abnormally hyperreflective at the active lesion site and associated with some degree of retinal pigment epithelium-choriocapillaris/choroidal optical shadowing in all patients. The posterior hyaloid was thickened and focally detached (over the lesion). Additional findings include tractional maculopathy (n = 2) and diffuse macular edema (n = 1). During follow-up, focal choriocapillaris/choroidal relative hyperreflectivity was observed at the former lesion site, and posterior vitreous detachment progressed in all patients. CONCLUSIONS: Our findings suggest that OCT may enable identification of subtle morphologic features previously underappreciated in patients with PRT, which may provide new insights about the disease pathophysiologic mechanisms.- - - - - - - - - - ranking = 0.66712750977568keywords = optic, edema (Clic here for more details about this article) |
5/16. toxoplasma gondii retinochoroiditis and optic neuritis in acquired immune deficiency syndrome. Report of a case.A 29-year-old man with acquired immune deficiency syndrome (AIDS) was found to have a retinochoroiditis and optic neuritis of his left eye. Results of fundus examination showed inflammatory and hemorrhagic retinal lesions consistent with retinitis due to cytomegalovirus infection. A computed tomographic (CT) scan demonstrated enlargement of the optic nerve. The eye was enucleated and results of histopathologic examination showed retinal necrosis with underlying choroiditis and an optic neuritis. Numerous encysted toxoplasma gondii organisms were present in the retina and tachyzoites were present in the optic nerve. To the authors' knowledge this is the second histologically documented case of toxoplasma optic neuritis in a patient with AIDS.- - - - - - - - - - ranking = 0.99861747067295keywords = optic (Clic here for more details about this article) |
6/16. Identification of toxoplasma gondii in paraffin-embedded sections by the polymerase chain reaction.We used the polymerase chain reaction to amplify dna fragments specific to toxoplasma gondii. The sensitivity of the technique allowed for the detection of as few as ten cultured T. gondii tachyzoites. We applied the same amplification technique to deparaffinized ocular sections from two cases of ocular toxoplasmosis. Although toxoplasmic cysts could only be seen in one eye by optical microscopy, polymerase chain reaction allowed the identification of the parasite in both cases. Our study indicates the feasibility of a sensitive dna-based assay to complement pathologic studies of an ocular parasitic disease.- - - - - - - - - - ranking = 0.11095749674144keywords = optic (Clic here for more details about this article) |
7/16. optic neuritis due to acquired toxoplasmosis.A pediatric patient with well documented acquired toxoplasmic optic neuritis is presented. Use of immunoglobulin m immunofluorescent antibody studies allow easier identification of recently acquired toxoplasmosis. Toxoplasmic optic neuritis and retinitis should be considered along with toxoplasmic meningitis or encephalitis as complications of acquired toxoplasmosis. Therapy is available which may decrease the duration of visual symptomatology and reduce residual visual impairment.- - - - - - - - - - ranking = 0.22191499348288keywords = optic (Clic here for more details about this article) |
8/16. Toxoplasmic retinochoroiditis presenting s serous detachment of the macula.Of the many causes of serous detachment of the macula, toxoplasmic retinochoroiditis is one of the least common. A case presented which responded to only medical treatment. The clinical picture of this case is consistent with the theory that the organisms may in some instances reach the retina from the optic nerve through an embryologic extension of the ventricular system of the brain. early diagnosis and treatment can prevent significant permanent visual loss as well as unnecessary retinal photocoagulation.- - - - - - - - - - ranking = 0.11095749674144keywords = optic (Clic here for more details about this article) |
9/16. Unusual ocular presentation of acute toxoplasmosis.Four patients with toxoplasmosis are reported with unusual presenting ocular lesions. One patient had an active lesion that appeared to involve the optic nerve as well as focal toxoplasmosis chorioretinitis at the macula. A second patient had a pale optic nerve in association with the classical chorioretinal scars of toxoplasmosis. The third patient had toxoplasmosis chorioretinitis of the macula with subretinal neovascularisation. The fourth patient had a branch artery occlusion complicating acute retinitis.- - - - - - - - - - ranking = 0.22191499348288keywords = optic (Clic here for more details about this article) |
10/16. Unusual presentation of acute ocular toxoplasmosis.Two unusual cases of ocular toxoplasmosis are presented. A 24 year old woman developed retinal and optic nerve neovascularization in conjunction with acute ocular toxoplasmosis. The neovascularization regressed with resolution of the inflammation. The possibility of retinal ischemia or inflammation alone as an etiology are discussed. A 19 year old woman developed optic nerve edema and a marked decrease in vision associated with a nasal toxoplasma lesion and a macular star. With resolution of the process, optic atrophy developed but visual acuity returned to normal. optic nerve edema and atrophy were felt to result from diffuse inflammation, but not from focal involvement in the nerve itself with the organism.- - - - - - - - - - ranking = 0.33563754887841keywords = optic, edema (Clic here for more details about this article) |
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