1/10. Demonstration of retroiridal extension of an epithelial membrane by ultrasound biomicroscopy: a clinicopathologic correlation.PURPOSE: To report the utilization of ultrasound biomicroscopy (UBM) in identifying the extension into the posterior segment of an epithelial membrane, as correlated by the histopathologic findings. METHOD: Case report. UBM findings before enucleation with histopathologic correlation. RESULTS: UBM demonstrated a membrane tracking from the posterior iris surface over the ciliary body and towards the retina. light microscopic examination disclosed the epithelial nature of this membrane. CONCLUSION: UBM can identify extension of an epithelial membrane into the posterior segment and thereby guide the approach to surgical management.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
2/10. Spontaneous iris stromal cyst: a case report and review of literature.Spontaneous iris stromal cysts are rare and usually are identified early in life. They resemble implantation iris cysts after nonsurgical and surgical trauma; both have an epithelium which usually is conjunctival in nature. However, in spontaneous iris stromal cysts, no ocular trauma history is found. We present a case report and review of literature.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
3/10. iris reconstruction with a multipiece endocapsular prosthesis in iridocorneal endothelial syndrome.iris reconstruction in cases of iridocorneal endothelial (ice) syndrome is extremely challenging because of the nature of the iris tissue, which is typically friable and poorly suited to suture repair. Reconstruction in such cases often requires artificial iris implantation. This report illustrates cataract extraction and iris reconstruction with a multipiece endocapsular iris prosthesis that can be inserted through a small incision. maintenance of a small incision size is a distinct advantage when glaucoma is coexistent in patients with ice syndrome. It also demonstrates the presence of an ice membrane over the anterior capsule and the importance of recognizing this membrane rather than confusing it with the anterior capsule when performing the capsulorhexis.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
4/10. Essential iris atrophy. A clinical, immunohistologic, and electron microscopic study in an enucleated eye.A 29-year-old woman had unilateral essential iris atrophy, corneal endothelial changes, and absolute glaucoma. The enucleated eye was examined by routine light microscopy. Separate portions of unfixed fresh frozen cornea were sectioned and reacted with monoclonal antibodies against keratins, vimentin, and inflammatory cell markers. Stains for filamentous actin (f-actin) were performed using the 7-nitro-benz-2-oxa-1,3-diazolylphallacidin (NBD phallacidin) probe. In addition, portions of cornea and iris were examined by scanning and transmission electron microscopy. Immunocytochemical stains with anti-keratin antibodies showed reactivity only in the corneal epithelium of the patient and normal control. Immunoreactivity with anti-vimentin antibodies was observed in corneal endothelium and keratocytes of the patient and control, but was negative in the epithelium. Staining for f-actin appeared more pronounced in the corneal endothelium of the patient. Scanning electron microscopy of the corneal endothelium showed irregularity in cell size and shape and filopodial processes characteristic of migrating cells. Transmission electron microscopy disclosed abnormalities of Descemet's membrane and endothelium with a posterior collagenous layer. The corneal endothelium displayed normal junctional complexes without desmosomal junctions or increased microvillus projections. Increased 10-nm cytoplasmic filaments were noted consistent with the expression of vimentin. Occasional chronic inflammatory cells perturbed the corneal endothelium and were detected within the endothelial layer. Alterations in the endothelium and Descemet's membrane suggest the acquired nature of this disease.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
5/10. iris microhemangiomas.iris microhemangiomas (IM) are benign proliferations of small, twisted blood vessels along the pupillary margin. They are usually bilateral and appear to be developmental in nature. IMs most commonly occur in patients with myotonic dystrophy and adult-onset diabetes mellitus, but have also been associated with respiratory disease, congential heart disease, and central retinal vein occlusion. Additionally, they may be found in individuals without obvious ocular or systemic abnormality. The etiology remains obscure. In this report, illustrative cases are followed by a brief discussion outlining typical clinical manifestations, etiological considerations, and possible implications.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
6/10. iris melanoma. nevus or malignancy?Although iris melanomas have an excellent prognosis when diagnosed and treated early, they should not be considered benign lesions. The authors report the orbital recurrence of a melanoma in a patient whose eye had been enucleated 30 years earlier because of an iris melanoma. The clinical, epidemiological and pathological characteristics of iris melanomas are summarized and compared to those of other uveal melanomas. The similarities suggest that iris melanomas are not by nature more benign than other uveal melanomas and that their better prognosis is due to the earlier detection allowed by their more obvious location.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
7/10. Bee sting of the cornea.Irreversible heterochromia-iridis, internal ophthalmoplegia, and punctate subcapsular lenticular opacities developed in a 9-year-old girl after she received a bee sting in her right cornea. These complications persisted even after an 11-month follow-up period. To the author's knowledge, this presentation is the first of its nature. The pathogenesis of these changes is discussed and the literature is reviewed.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
8/10. An ultrastructural study of carcinoid tumor of the iris.An iris tumor developed in a 37-year-old woman who had had a bronchial carcinoid tumor resected nine years previously. The iris tumor was locally excised with a modified trabeculectomy approach. Histologic studies showed it to be a metastatic carcinoid tumor. Electron microscopy demonstrated typical dark and pale carcinoid cells with neurosecretory granules, basal bodies, and apical microvilli. The cisternae of the granular endoplasmic reticulum were disposed in a series of concentric rings encapsulating a central core of mitochondria. This unusual type of subcellular organization and specialization is probably a reflection of the slow-growing and highly differentiated nature of the iris tumor.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
9/10. Shiny spots in the iris in chronic uveitis.A case of chronic uveitis with shiny spots in the iris is described. Histologically the shiny spots proved to be Russel bodies. The nature of the Russel bodies is discussed.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
10/10. Primary iris stromal cysts.The clinical and histopathologic features of four cases of primary iris stromal cysts are reported. Though the histologic characteristics of iris stromal cysts have been well described by previous authors, their exact embryologic origin is not clear. Also, because of the relatively uncommon nature of these lesions, the most appropriate management is not well defined. In our series, routine histopathologic studies were supplemented with immunohistochemical stains for cytokeratins and s100 proteins, results of which suggested an origin from surface ectoderm. All of our patients required surgical management, although spontaneous involution of a temporary nature was observed in one case, and recurrences following incomplete removal were common.- - - - - - - - - - ranking = 2keywords = nature (Clic here for more details about this article) |
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