1/8. Hepatoid adenocarcinoma of the urinary bladder. An unusual neoplasm.A new case of hepatoid adenocarcinoma was diagnosed in fragments obtained at transurethral resection (TUR) from a 71-year-old man who had complained of haematuria. The tumour was composed of trabeculae and small solid nests of polygonal atypical cells simulating hepatocarcinoma, together with glandular areas of an otherwise typical adenocarcinoma. immunohistochemistry showed cytoplasmic reactivity to AFP, AAT, albumin and CAM 5.2. Membrane reactivity was seen in EMA immunostaining, and there was also positivity to polyclonal CEA following a canalicular pattern. Immunoperoxidase studies of hepatocyte growth factor (HGF) and its receptor, c-met, were positive. Their expression may be related to the aggressive behaviour of this tumour.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
2/8. Interdigitating dendritic cell sarcoma: a report of four paediatric cases and review of the literature.AIMS: To report a series of four paediatric cases of interdigitating dendritic cell sarcoma (IDCS) and add to the known extranodal sites of occurrence for this tumour. neoplasms derived from interdigitating dendritic cells are rare, with only 33 cases being reported in the literature (medline search). These tumours usually occur in lymph nodes in the adult population. methods AND RESULTS: The patients were a 10-year-old girl with a large soft tissue mass bulging into the left chest, a 12-year-old girl with a right paraspinal mass, a 21-month-old boy with generalized lymphadenopathy and hepatosplenomegaly and a 6-year-old girl with a large bladder mass. paraffin blocks and haematoxylin and eosin slides were available in all cases. In addition, immunohistochemistry and electron microscopy were performed. A diagnosis of IDCS was made in all cases. CONCLUSION: The diagnosis of IDCS can rarely be entertained on clinical information alone. Microscopically, there is a wide spectrum of features. Thus, immunohistochemistry and electron microscopy are crucial in making the diagnosis. The differential diagnosis includes inflammatory pseudotumour, follicular dendritic cell sarcoma, true histiocytic lymphoma, malignant Langerhans cell histiocytosis, anaplastic large-cell lymphoma, melanoma, and a range of sarcomas. IDCS displays aggressive behaviour and approximately half of the patients die of the disease.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
3/8. Orbital metastasis from transitional cell carcinoma of the bladder.Transitional cell carcinoma (TCC) is a common bladder tumour, 10-15% of which will exhibit invasive behaviour. About 50% of patients with invasive TCC will eventually develop distant metastases, usually to lymph nodes, lung or bones. The case is reported of bladder TCC metastasizing to the orbit.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
4/8. Bladder carcinosarcoma: a case observation.carcinosarcoma of the bladder is a very unusual neoplasm that arises more frequently in males with a greater incidence in the seventh decade of life. There are no patognomonic clinical findings or symptoms to address its presence. Symptoms, as for other bladder cancers, are fundamentally represented by haematuria and dysuria. It has a very aggressive clinical behaviour and it is histologically characterized by a malignant epithelial component associated with a sarcoma-like (sarcomatoid) component variably represented.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
5/8. Bladder transitional cell carcinoma.We present a case of urinary bladder carcinoma in a child aged 13 that followed a benign course. This confirms the idea that epithelial bladder cancer in children pursues, a much less aggressive behaviour than in the adult, possibly on the basis of its well-differentiated nature. Despite the rarity of the lesion, it should not be overlooked in the differential diagnosis of haematuria in children.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
6/8. A case of inverted papilloma of the ureter: is the dna ploidy pattern associated with occurrence of transitional cell carcinoma of the bladder?We describe herein a case of inverted papilloma of the ureter, in which transitional cell carcinoma of the bladder developed twenty-three months after nephroureterectomy. Flow cytometric analysis of formalin-fixed and paraffin-embedded archival material of the inverted papilloma revealed dna aneuploidy pattern and relatively high percentage of s phase. Retrospectively, dna measurement thus provided the predictive value regarding biological activity and the clinical behaviour of the present case.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
7/8. Imaging of small cell carcinoma of the male urogenital tract.Five cases of small cell carcinoma (three of the prostate and two of the bladder) are described to illustrate the unusual behaviour of these tumours. Cerebral, hepatic and bulky lymph node spread with large volume local disease occurred. The role the radiologist may play in these diseases is discussed.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
8/8. Villous adenoma of the bladder.Villous adenomas of the bladder are rare tumors and up to now they have not been seen to undergo malignant transformation. We report a case of villous adenoma of the bladder with areas of adenocarcinoma in a 72-year-old man. We describe all the morphological, histochemical and immunohistochemical features characterizing this tumor. We recommend adequate pathological sampling and a thorough follow-up of patients with villous adenoma. The prognosis and the behaviour of these adenomatous papillary lesions, morphologically similar to colonic adenomas, in the bladder is unclear. We report a case with focal area of adenocarcinoma and review the literature.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |