1/4. mycobacterium marinum infection in a renal transplant recipient.BACKGROUND: Infections with atypical mycobacteria occur more frequently in patients with solid organ transplants than in the normal host. methods: We report a case of cutaneous mycobacterium marinum infection in a renal transplant recipient. The patient presented with nodules on the forearm after returning from a fishing trip and was treated for cellulitis without success. RESULTS: Cultures of a biopsy of the lesion grew M. marinum. The patient was treated with ethambutol and ciprofloxacin with a good response; however, 9 months of treatment were required for complete resolution. CONCLUSION: Immunosuppressive therapy for renal transplantation increases susceptibility to a variety of opportunistic infections. A patient who presents with nodules on the extremities should be questioned regarding contact with fish, aquatic environments, or fish tank water, in which case infection with M. marinum should be considered. The diagnosis and treatment of this infection in transplant recipients is discussed.- - - - - - - - - - ranking = 1keywords = environment (Clic here for more details about this article) |
2/4. Concomitant mycobacterium tuberculosis and aspergillus niger infection in a patient with acute myeloid leukemia.Primary cutaneous infection by Aspergillus spp. is an uncommon form of aspergillosis in patients with severe immunosuppression, e.g. patients with hiv infection or hematological malignancies. Disruption of the dermal integrity by trauma or maceration, followed by colonization of the wound by Aspergillus spp. creates a suitable environment for cutaneous infection. Despite aggressive therapy with amphotericin, primary cutaneous aspergillosis can lead to disseminated disease with fatal consequences. Tuberculosis is another rare infection in patients with hematological malignancies, but when present it is usually disseminated. We present a 46-year-old woman with acute myeloid leukemia who developed concomitantly mycobacterium tuberculosis and aspergillus niger infection. Cutaneous aspergillosis was diagnosed during neutropenia after induction therapy, which later became disseminated disease during antifungal therapy. Tuberculosis infection was diagnosed in a scalene lymph node biopsy specimen. The patient achieved remission of her underlying disease and responded very well to antituberculous and antifungal therapy.- - - - - - - - - - ranking = 1keywords = environment (Clic here for more details about this article) |
3/4. Atypical Mycobacterium furunculosis occurring after pedicures.mycobacterium fortuitum complex are rapidly-growing nontuberculous mycobacteria found ubiquitously in the environment including, water, soil, dust, and biofilms. M fortuitum has been reported to cause skin and soft-tissue infections in association with nail salon footbath use during pedicures. Four cases of M fortuitum complex furunculosis are reported that occurred after pedicures in the Cincinnati, ohio/Northern kentucky area. Dermatologists and clinicians should consider mycobacterial infections from the M fortuitum complex when patients present with nonhealing furuncles on the lower legs and should inquire about recent pedicures. Early recognition and institution of appropriate therapy are critical. public health measures should be explored to protect against such infections, given the recent popularity of the nail care industry.- - - - - - - - - - ranking = 1keywords = environment (Clic here for more details about this article) |
4/4. Cutaneous inoculation tuberculosis secondary to 'jailhouse tattooing'.Cutaneous inoculation tuberculosis is rare in the united states today. When seen, it usually occurs in individuals whose occupations or environments place them at increased risk for exposure to mycobacterium tuberculosis. The reaction of the skin to M tuberculosis infection is polymorphous and depends upon the interplay of bacterial virulence and host immunity. Thus, both a high index of suspicion and positive cultures are required to make the diagnosis. Herein, we report a case of cutaneous inoculation tuberculosis occurring in a tattoo.- - - - - - - - - - ranking = 1keywords = environment (Clic here for more details about this article) |