11/133. Protease inhibitor-associated angiolipomatosis.Treatment with protease inhibitors in some persons infected with hiv-1 is associated with a syndrome of lipodystrophy manifesting as peripheral lipoatrophy, relative central adiposity, insulin resistance, and serum lipid abnormalities. We report 3 cases of hiv-1 infected patients who experienced symptomatic angiolipomas shortly after starting antiretroviral therapy including the protease inhibitor indinavir. The mechanism behind this observation may be similar to that of previously reported protease inhibitor-associated fat redistribution, but instead involving the adipose tissue of discrete uncommon benign tumors.- - - - - - - - - - ranking = 1keywords = behind (Clic here for more details about this article) |
12/133. Chest wall parachordoma.A 21-year-old woman with a painful chest wall mass was found to have a parachordoma (PC). The tumor arose from the fifth intercostal space. A wide chest wall resection including the tumor and a 2.5 cm free margin and the subsequent reconstruction with a Gore-Tex soft tissue patch covered with a latissimus dorsi rotational flap was performed. To our knowledge, chest wall parachordoma has not been previously reported in the medical literature.- - - - - - - - - - ranking = 1.1403191127977keywords = chest (Clic here for more details about this article) |
13/133. Atypical lipomatous tumors with smooth muscle differentiation: report of two cases.Two cases of soft-tissue atypical lipomatous tumors with areas of smooth muscle cell differentiation are presented. The patients were a 72-year-old man (Case 1) and a 62-year-old woman (Case 2); their neoplasms were located in the left inguinal region and on the chest, respectively. The adipocytic component in Case 1 contained cells with nuclear atypism and lipoblasts. Case 2 showed only slight nuclear atypism and lacked any lipoblasts. Smooth muscle fascicles were composed of well-differentiated cells with a few mitoses having none or only a slight atypism. They expressed muscle-specific actin and desmin in both cases. No recurrence was recorded during the follow-up time.- - - - - - - - - - ranking = 0.38010637093256keywords = chest (Clic here for more details about this article) |
14/133. Extramedullary myeloid cell tumour: presentation as anterior chest wall mass during AML relapse.Acute myeloid leukaemia is an uncommon but an important cause of soft tissue swellings. Such extrameningeal, extramedullary leukaemic infiltrates are called extramedullary myeloid cell tumours. Despite their large size they may respond well to chemotherapy and local radiotherapy, as is demonstrated in this case.- - - - - - - - - - ranking = 1.5204254837302keywords = chest (Clic here for more details about this article) |
15/133. Sacrococcygeal extraspinal ependymomas: the role of coccygectomy.BACKGROUND: Ependymomas, the common glial tumors of the spinal cord, occur occasionally outside the central nervous system and are called exstraspinal ependymomas (EEP). EEPs are found primarily in sacrococcygeal region during childhood. The pathogenesis and the treatment of the sacrococcygeal (SC) ependymomas are still controversial. Therefore, we present our case with metaanalysis of other case reports to determine the optimal treatment modality for SC EEPs. methods: A metaanalysis of case reports of SC EEPs, including the current case, was conducted. Also all available case reports of EEPs, without age limit, were analyzed to determine the distribution of EEPs localization. RESULTS: EEPs usually are found in teratoma localizations such as the SC area, ovary, paraovarian structures, and medastinum. The distribution of EEPs localization differs with age. Local recurrence rate of EEPs after coccyx excision is zero, however, it increases to 71% when the coccyx was left behind. CONCLUSION: The identical clinical characteristics of the SC teratomas and EEPs imply that the SC EEPs may be monophasic teratomas as their ovarian counterparts are named. coccyx excision is an important part of the surgical treatment of these tumors, with an apparent decrease in the recurrence rate.- - - - - - - - - - ranking = 1keywords = behind (Clic here for more details about this article) |
16/133. Elastofibroma of the neck.Elastofibromas are benign lesions of the chest wall. We describe the first reported case of elastofibroma in the neck. Imaging features as well as location of the lesion were atypical. On computed tomography and magnetic resonance imaging the lesion contained a marked preponderance of fat, because the lesion arose within fat.- - - - - - - - - - ranking = 0.38010637093256keywords = chest (Clic here for more details about this article) |
17/133. thoracic wall lipoblastoma: a case report and review of histopathology and cytogenetics.A rare case of a successfully excised intra- and extrathoracic lipoblastoma of the anterior chest wall in a 13-month-old female infant is reported. Histopathology and cytogenetical analysis established the diagnosis of a lipoblastoma. The differential diagnosis, histology and cytogenetical evaluation of lipomatous neoplasms are discussed. Karyotypic analysis may be of use in diagnostically difficult cases owing to the characteristic alterations in 18q11-13. A complete resection of lipoblastomas is feasible and advantageous with no need for a mutilating radical excision.- - - - - - - - - - ranking = 0.38010637093256keywords = chest (Clic here for more details about this article) |
18/133. Late recurrence of small-cell lung cancer: a case report.A 67-year-old man was admitted with small-cell lung cancer (SCLC). The patient was given four courses of platinum-containing chemotherapy followed by chest irradiation, and good partial response (PR) was obtained. The patient did well for 4 years, until he sought treatment for a painful subcutaneous tumor. Chest computed tomography scan revealed the mass extending from the tumor in lung parenchyma with osteolytic lesion of the third rib bone. Pathologic examination of the subcutaneous lesion revealed SCLC. The patient was given two courses of the same combination chemotherapy administered as initial therapy. Regression of the mass was observed, and the response was evaluated as a good PR. How to approach late recurrence of SCLC is discussed.- - - - - - - - - - ranking = 0.38010637093256keywords = chest (Clic here for more details about this article) |
19/133. Elastofibroma dorsi: elaboration of cytologic features and review of its pathogenesis.Elastofibroma is a slow-growing soft tissue lesion characteristically found between the inferior scapula and chest wall. Because it behaves clinically in a benign manner, fine-needle aspiration (FNA) represents the simplest and quickest method of obtaining a definitive diagnosis, thus obviating more invasive means of obtaining a tissue diagnosis. However, due to the nature of this lesion a correct diagnosis can inadvertently be missed. Herein we describe the findings of a recent FNA that obtained abundant diagnostic material and elaborate upon the spectrum of cytologic features of the elastic fibers that can be identified. These features should be recognized, since aspiration biopsy in elastofibromas can lead to hypocellular smears. In addition, we discuss recent developments in the pathophysiology of elastic fibers and their application toward understanding the generation of an elastofibroma.- - - - - - - - - - ranking = 0.38010637093256keywords = chest (Clic here for more details about this article) |
20/133. Nuchal-type fibroma in two related patients with Gardner's syndrome.Nuchal-type fibroma is a distinct subcutaneous and dermal fibrous tissue proliferation that has been previously definitely identified in one patient with Gardner's syndrome and has been possibly present in two others. Gardner's syndrome is an autosomal-dominant condition with variable expressivity that comprises epidermoid cysts, fibrous tumors, osteomas, intestinal polyposis, as well as other findings. We report two cases of nuchal-type fibroma presenting in a 13-year-old boy in the right upper back and in his 60-year-old grandfather in the upper chest at the posterior axillary line. Both individuals carried a diagnosis of Gardner's syndrome and neither of them had diabetes. Although the boy has as of now only presented with cutaneous manifestations of Gardner's syndrome, his grandfather has exhibited both cutaneous and intestinal evidence of this syndrome. In addition, the boy's mother and her sister have documented Gardner's syndrome. light microscopic findings of nuchal-type fibroma from both patients include paucicellular, haphazardly arranged collagen bundles with entrapped adipose tissue. A marked diminution of elastic fibers was noted with Van-Gieson stains. The lesions were diffusely positive for CD34 and contained a few factor xiiia-positive cells. Electron microscopic analysis revealed no differences between the collagen comprising the nuchal-type fibroma as compared with control dermal collagen obtained from skin away from the tumor. These cases strengthen the view that there is an association between nuchal-type fibroma and Gardner's syndrome.- - - - - - - - - - ranking = 0.38010637093256keywords = chest (Clic here for more details about this article) |
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