Cases reported "Rectal Diseases"

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1/6. Weekly administration of paclitaxel attenuated rectal stenosis caused by multiple peritoneal recurrence 8 years after the resection of gastric carcinoma.

    We report a patient with rectal stenosis caused by peritoneal recurrence 8 years after a curative resection of advanced stage gastric carcinoma; the recurrence was effectively treated with the weekly administration of paclitaxel. The patient was a 66-year-old Japanese woman who was admitted to our hospital complaining of abdominal pain and frequent bowel movements. She had undergone total gastrectomy, due to advanced-stage gastric carcinoma with extensive lymph node metastasis, 8 years before, and had taken an oral anticancer agent, fluoropyrimidine, for 4 years after the operation. Colonofiberscopy performed on admission revealed circumferential rectal stenosis located 10 cm from the anal verge. barium enema study demonstrated extensive poor expansion of the upper and lower rectum and irregularity of the descending colon. Abdominal computed tomography (CT) scanning revealed wall thickening in the rectum and descending colon. These findings were compatible with rectal stenosis caused by the peritoneal recurrence of gastric carcinoma. Weekly administration of paclitaxel was started. The abdominal symptoms soon disappeared when the second cycle of paclitaxel was completed, and they have not appeared since then. The rectal stenosis was attenuated, as confirmed by imaging analyses. Weekly paclitaxel has been effective for more than 13 months, suggesting that the patient is in a state of tumor dormancy of recurrent gastric carcinoma.
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2/6. Rectal ulcer with massive haemorrhage due to activated charcoal treatment in oral organophosphate poisoning.

    A 42-year-old woman who had ingested a large amount of fenitrothion emulsion was admitted and treated. Treatments consisted of mechanical ventilation, intravenous administration of atropine and pralidoxime and repeated injection of activated charcoal with magnesium sulphate via a nasogastric tube. The patient developed massive rectal bleeding just after she had passed several hard masses of charcoal on the 10th day. Surgical haemostasis of the rectal ulcer was needed to control the haemorrhage.
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3/6. The water soluble contrast enema after rectal anastomosis.

    A retrospective study of 135 consecutive postoperative water soluble contrast enemas has been performed to establish the safety of the technique and indications for its use. Normal and abnormal appearances at various levels of rectal anastomosis have been described. Postrectal fluid collections are associated with anastomotic dehiscence and may be a cause rather than effect. One low colorectal anastomosis was disrupted during administration of the enema; the procedure was otherwise safe and free from complication. The postoperative water soluble contrast enema is presented primarily as a research tool to define the true anastomotic leak rate, but may be useful in the diagnosis of a postrectal collection and to define the extent of an established leak.
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4/6. Acute renal failure in a patient with chronic glomerulonephritis after the administration of luteinizing hormone-releasing hormone analogue given for rectal obstruction due to prostate cancer.

    We report a case in which rectal obstruction due to prostate cancer was exacerbated due to an ileus after the administration of luteinizing hormone-releasing hormone analogue. The obstruction to led to copious vomiting, dehydration and renal failure which necessitated hemodialysis. Improvement of the patient was noted four weeks after the start of hormonal treatment with a decrease in rectal obstruction concomitant with decreases in testosterone and prostate specific antigen levels.
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5/6. Neonatal rectovaginal tear during cesarean section.

    Intrauterine rectovaginal tears are an infrequent and life-threatening complication of breech presentation. One previous case has been presented in the literature with a fatal outcome. The authors report a second case of a severe rectovaginal intrauterine tear sustained during cesarean delivery. Prompt administration of antibiotics followed by debridement and primary repair was performed with a successful outcome.
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6/6. Treatment of chronic post-radiation proctitis with oral administration of sucralfate.

    Several nonsurgical approaches to the treatment of postradiation proctitis have been described, but no effective conservative treatment has yet been established. As an alternative to the usual treatment, three cases of chronic postradiation proctitis with hemorrhage were successfully treated with oral administration of sucralfate, with resultant decreased bleeding in long term follow-up period. Oral sucralfate may provide a novel approach to the treatment of intractable postradiation proctitis.
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