1/9. One-stage debridement and knee fusion for infected total knee arthroplasty using the hybrid frame.In 1997 and 1998, a hybrid fixator was used for a one-step arthrodesis in 2 cases of infected total knee arthroplasty. One patient had rheumatoid arthritis, and the other had an infected reimplant arthroplasty. Neither patient was a candidate for reimplantation. Fusions were achieved with the hybrid frame in an average of 10 weeks. All signs of local and systemic infections were eliminated. After 24 months for patient 1 and 37 months for patient 2, both are infection-free and ambulatory without the aid of a wheelchair.- - - - - - - - - - ranking = 1keywords = candida (Clic here for more details about this article) |
2/9. Delayed reimplantation arthroplasty for candidal prosthetic joint infection: a report of 4 cases and review of the literature.Fungal prosthetic joint infection (PJI) is rare, with Candida species being the most frequently reported pathogen in the medical literature. The risk of relapse following delayed reimplantation arthroplasty for candidal PJI is unknown. We describe 4 new cases and summarize 6 previously reported cases of candidal PJI treated with delayed reimplantation arthroplasty. Ninety percent of the patients received antifungal therapy. Eight patients received amphotericin b either alone or in combination with other antifungals. One patient received fluconazole alone. The median duration of time from resection arthroplasty to reimplantation for total hip and total knee arthroplasties was 8.6 and 2.3 months, respectively. Eight patients did not have relapse of candidal PJI following delayed reimplantation arthroplasty after a median duration of follow-up of 50.7 months (range, 2--73 months). Candidal PJI can be successfully treated with delayed reimplantation arthroplasty after receipt appropriate antifungal therapy.- - - - - - - - - - ranking = 7keywords = candida (Clic here for more details about this article) |
3/9. Infectious complications of old nonfunctioning arteriovenous grafts in renal transplant recipients: a case series.Occult infection of old nonfunctioning arteriovenous grafts (AVGs) is frequent among hemodialysis patients. It is a risk factor for bacteremia and serious AVG-related infection. Immunocompromised patients are at increased risk of dissemination of occult AVG infection. We present a series of five renal transplant recipients who developed acute life-threatening infections that originated in their old nonfunctioning AVGs. Their presenting symptoms were noticeably varied. In two patients, infection of the AVG was characterized by local physical signs of infection around the AVG. In three patients, no physical signs of AVG infection were detected by physical examination. Among these, two presented with bacteremia, and one presented with failure to thrive. Detection of AVG infection in the absence of local signs of infection requires a high index of suspicion. Surgical resection and antimicrobial treatment led to a complete cure in four of these patients. One patient developed recurrent bacterial endocarditis and died. Old nonfunctioning AVGs are potential sources of serious infection in renal transplant recipients. Renal transplant recipients with old nonfunctioning AVGs who present with unexplained bacteremia, fever of unknown origin, or failure to thrive should be investigated for occult AVG infection. Screening for occult infection of the old nonfunctioning AVG may be considered before kidney transplantation, especially if the candidate gives a history of previous bacteremia or fever of unknown origin.- - - - - - - - - - ranking = 1keywords = candida (Clic here for more details about this article) |
4/9. Successful medical treatment of candida albicans in mechanical prosthetic valve endocarditis.Fungal prosthetic valve endocarditis is particularly serious, and is usually a result of nosocomial candidaemia. This report describes a patient with candida albicans prosthetic valve endocarditis in whom surgery was believed to be contraindicated. After 45 d of amphotericin b, treatment was continued with fluconazole daily with a follow-up of 16 months, with no recurrent or adverse effects.- - - - - - - - - - ranking = 1keywords = candida (Clic here for more details about this article) |
5/9. Long-term oral ciprofloxacin in the treatment of prosthetic valve endocarditis due to pseudomonas aeruginosa.Prosthetic valve endocarditis caused by pseudomonas aeruginosa is refractory to medical treatment alone and early valve replacement is necessary. We describe a 40-year-old patient in whom endocarditis developed in the early postoperative period, and reoperation was not considered feasible. ciprofloxacin was administered orally in order to suppress bacteremia for 36 months. Long-term oral ciprofloxacin may provide an opportunity in the treatment of prosthetic valve endocarditis caused by Ps. aeruginosa in patients who are unfavorable candidates for reoperation.- - - - - - - - - - ranking = 1keywords = candida (Clic here for more details about this article) |
6/9. Candidal prosthetic hip infection in a patient with previous candidal septic arthritis.We describe the case of a patient with chronic monocytic leukemia who underwent total hip arthroplasty (THA) for hip arthrosis. The patient has a history of candida albicans arthritis of the same joint 5 months before THA surgery. Seven months after the prosthetic joint surgery, the patient developed a C albicans prosthetic infection that was successfully treated with amphotericin b and prosthesis removal. At surgery, the patient was believed cured of the candidal infection. risk of infection after prosthetic joint surgery in patients with previous fungal joint infections has not been fully investigated. A lengthy infection-free follow-up period is probably necessary but may not be sufficient to prevent the occurrence of postoperative infections in these patients.- - - - - - - - - - ranking = 5keywords = candida (Clic here for more details about this article) |
7/9. Long-term suppressive therapy for Candida parapsilosis-induced prosthetic valve endocarditis.Prompt valve replacement is advocated in patients in whom candidal prosthetic valve endocarditis develops. Unfortunately, some patients with this condition are considered nonsurgical candidates, and they are unable to tolerate long-term administration of amphotericin b with or without flucytosine. Herein we describe a patient with Candida parapsilosis-induced prosthetic valve endocarditis in whom oral administration of fluconazole during an 11-month period successfully suppressed the fungal infection. Three previously published cases indicate that long-term noncurative suppressive therapy for C. parapsilosis-induced prosthetic valve endocarditis may allow prolonged symptom-free survival for such patients.- - - - - - - - - - ranking = 2keywords = candida (Clic here for more details about this article) |
8/9. Candida prosthetic valve endocarditis: prospective study of six cases and review of the literature.Candida prosthetic valve endocarditis (PVE) is a rare entity; however, its incidence is expected to increase given the recent increase in incidence of nosocomial bloodstream candida infection. This report reviews six cases of candida PVE studied prospectively plus 12 cases previously reported in the literature. Transesophageal echocardiography was more sensitive than transthoracic echocardiography in detecting vegetations. Valvular replacement combined with antifungal therapy has been the standard treatment. However, successful therapy with long-term administration of oral fluconazole has been reported for five patients. The mortality due to candida PVE was high, especially when PVE was complicated by congestive heart failure and persistent fungemia. For uncomplicated PVE, the mortality rate for patients receiving antifungal therapy alone (40%) was no worse than for those receiving combined medical and surgical therapy (33%).- - - - - - - - - - ranking = 3keywords = candida (Clic here for more details about this article) |
9/9. candida glabrata prosthesis infection following pyelonephritis and septicaemia.candida glabrata is a well-known cause of lower urinary tract infections. Systemic infections caused by this organism are less common, but have increased dramatically in recent years. Prosthesis infection caused by C. glabrata is extremely rare. We report a case of prosthesis failure due to C. glabrata 5 y after candidaemia and pyelonephritis caused by this organism. The same C. glabrata strain was isolated from both infections, as confirmed by the random amplified polymorphic dna (RAPD) method.- - - - - - - - - - ranking = 1keywords = candida (Clic here for more details about this article) |