11/176. Neurological complications associated with mycoplasma pneumoniae infection. A case report.mycoplasma pneumoniae (MP) is a frequent cause of respiratory tract infection. Extra-pulmonary manifestations may be neurological with variable expression, encephalitis being the most frequent. meningitis, myelitis or polyradiculoneuritis are also reported. The pathophysiology of neurological manifestations remains poorly understood. Although not isolated from cerebral tissue, MP was reportedly detected in cerebro-spinal fluid (CSF) on several occasions. We report the case of a five-year-old girl who presented with fever, then pneumonia, and later developed spastic quadriparesis. MP was identified as the causative agent, evidenced by the presence of specific antibodies in both serum and CSF. The identification of a central nervous syndrome associated with confirmed MP infection extends the list of similar cases documented in individuals younger than 17 years of age.- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
12/176. Severe acute lung injury caused by mycoplasma pneumoniae: potential role for steroid pulses in treatment.Published evidence of pathogenetic mechanisms of acute respiratory distress syndrome (ARDS) in mycoplasmal lung infections suggests that the pulmonary injury is related to a cell-mediated immune response. Therefore, steroids may play a role in the treatment of severe cases. We describe a patient who had mycoplasma pneumoniae pneumonia that progressed to severe ARDS requiring mechanical ventilation and who had improvement with prednisolone pulses.- - - - - - - - - - ranking = 0.16666666666667keywords = infection (Clic here for more details about this article) |
13/176. Neurological symptoms in patients whose cerebrospinal fluid is culture- and/or polymerase chain reaction-positive for mycoplasma pneumoniae.We describe 13 patients with neurological signs and symptoms associated with mycoplasma pneumoniae infection. M. pneumoniae was isolated from the cerebrospinal fluid (CSF) of 9 patients: 5 with meningoencephalitis, 2 with meningitis, and 1 with cerebrovascular infarction. One patient had headache and difficulties with concentration and thinking for 1 month after the acute infection. M. pneumoniae was detected, by means of PCR, in the CSF of 4 patients with negative culture results. Two had epileptic seizures, 1 had blurred vision as a consequence of edema of the optic disk, and 1 had peripheral nerve neuropathy.- - - - - - - - - - ranking = 0.33333333333333keywords = infection (Clic here for more details about this article) |
14/176. Severe hemolytic anemia and excessive leukocytosis masking mycoplasma pneumonia.The formation of cold agglutinins is frequently observed during mycoplasma pneumoniae infections. Nevertheless, severe hemolysis is exceptional. We report a case of life-threatening hemolytic anemia caused by M. pneumoniae. As the leucocyte count was excessively elevated, the differential diagnosis primarily comprised hematological malignancies. The presence of cold agglutinins indicated the correct diagnosis, which was confirmed by highly elevated levels of both IgG and IgM antibodies to M. pneumoniae and a chest X-ray suggestive of atypical pneumonia. The patient was treated with roxithromycin and showed a favorable recovery within ten days after admission. This case demonstrates that, even in patients with clinically mild pneumonia, M. pneumoniae may be the cause of severe anemia.- - - - - - - - - - ranking = 0.16666666666667keywords = infection (Clic here for more details about this article) |
15/176. Fulminant mycoplasma pneumoniae pneumonia.A 64-year-old woman, who was previously in good health was admitted because of progressive respiratory distress. Her chest radiograph revealed bilateral widespread alveolar infiltrates. She was given a diagnosis of pneumonia caused by mycoplasma pneumoniae serologically, acute respiratory distress syndrome, and disseminated intravascular coagulation. She died of multiple organ failure despite intensive therapy with mechanical ventilation, intravenous erythromycin and corticosteroids, continuous hemodiafiltration, and plasma exchange. Although mycoplasma pneumoniae infection is usually a benign self-limited disease, this case emphasizes its potentially serious nature even in normal healthy individuals.- - - - - - - - - - ranking = 0.16666666666667keywords = infection (Clic here for more details about this article) |
16/176. Extensive myelitis associated with mycoplasma pneumoniae infection: magnetic resonance imaging and clinical long-term follow-up.Myelitis is a severe neurological complication associated with mycoplasma pneumoniae infections. Little is known about the extent and the reversibility of this myelitis, and reports on the value of spinal imaging are inconclusive. To obtain more information on the diagnostic and prognostic value of spinal magnetic resonance imaging (MRI) we studied the clinical course and MRI long-term follow-up of two patients with extensive myelitis associated with M. pneumoniae infection. The neuroradiological findings were correlated with the clinical extent of the spinal syndrome, but their reversibility preceded clinical improvement. These preliminary findings indicate that follow-up spinal MRI may give valuable prognostic information in cases of M. pneumoniae associated myelitis and warrant further more systematic studies to ascertain the relationship between spinal MRI findings and prognosis.- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
17/176. Brainstem and striatal encephalitis complicating mycoplasma pneumoniae pneumonia: possible benefit of intravenous immunoglobulin.Encephalitides of the brainstem and the striatum associated with mycoplasma pneumoniae infection are believed to be mediated by an autoimmune process triggered by the organism, a toxin or direct invasion by the organism itself. Inability to identify M. pneumoniae from cerebrospinal fluid by culture or polymerase chain reaction suggested a possible immunologic process. A trial of intravenous immunoglobulin in a critically ill patient with encephalitis that developed in parallel to M. pneumoniae pneumonia was associated with neurologic improvement within 48 h of treatment.- - - - - - - - - - ranking = 0.16666666666667keywords = infection (Clic here for more details about this article) |
18/176. Lemierre's syndrome with spondylitis and pulmonary and gluteal abscesses associated with mycoplasma pneumoniae pneumonia.Lemierre's syndrome, a systemic anaerobic infection caused by fusobacterium necrophorum, is characterized by an acute oropharyngeal infection, septic thrombophlebitis of the internal jugular veins, sepsis, and multiple metastatic infections. It commonly leads to pulmonary parenchymal abscesses and occasionally to septic arthritis, osteomyelitis, or liver or spleen abscesses. Reported here is a case of spondylitis and pulmonary and gluteal abscesses that occurred as part of a classic presentation of Lemierre's syndrome. Treatment with imipenem and clindamycin was successful.- - - - - - - - - - ranking = 0.5keywords = infection (Clic here for more details about this article) |
19/176. Fatal disseminated intravascular coagulation caused by mycoplasma pneumoniae.We report fatal disseminated intravascular coagulation caused by mycoplasma pneumoniae infection in a 7-year-old white boy. The diagnosis was based on relevant clinical material, absence of any other infections, a 4-fold rise in titer of complement fixation for M. pneumoniae and open lung biopsy findings. We discuss the association between M. pneumoniae and autoimmune mechanism.- - - - - - - - - - ranking = 0.33333333333333keywords = infection (Clic here for more details about this article) |
20/176. mycoplasma pneumoniae infection, meningoencephalitis, and hemophagocytosis.central nervous system manifestations are a common extrapulmonary complication of mycoplasma pneumoniae infection, of which encephalitis is a well-recognized abnormality in children. In this report the first description of M. pneumoniae infection simultaneously complicated by meningoencephalitis and hemophagocytosis is presented.- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
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