Cases reported "Osteolysis"

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1/50. Mandibular mass as the presenting manifestation of IgM myeloma in a 22-year-old man.

    We report here the youngest known IgM myeloma patient to have presented with a mandibular mass. A 22-year-old Chinese man sought medical attention due to a mass over his right mandible that had been growing progressively for 6 months. A solitary osteolytic lesion in the right mandible was identified radiologically. Incisional biopsy revealed the presence of plasma cells of monoclonal origin, as evidenced by the exclusively positive staining of the kappa light chain. The diagnosis of multiple myeloma with mandibular involvement was confirmed by bone marrow examination. Further tests, including immunoglobulin electrophoresis and assay of the serum levels of kappa and lambda light chains, demonstrated that his myeloma was of the IgM, kappa subtype. The patient achieved a nonsustained partial response to six courses of melphalan and prednisolone therapy and palliative radiotherapy.
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ranking = 1
keywords = mandible
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2/50. Failure of a metal-on-metal total hip arthroplasty from progressive osteolysis.

    Ultra-high-molecular weight polyethylene (UHMWPE) wear, debris-induced osteolysis is a frequent cause of failure of total hip arthroplasty. Metal-on-metal total hip arthroplasty eliminates the generation of UHMWPE particulate debris. Although the volumetric wear of a metal-on-metal articulation may be lower than a metal-UHMWPE articulation, the number of particles may be higher. osteolysis can develop in response to metallic and UHMWPE debris. The following case of massive osteolysis associated with large amounts of cobalt-chrome wear debris shows adhesive and abrasive wear mechanisms, as well as wear caused by third-body cobalt-chrome debris and impingement of the femoral component against the rim of the acetabular cup, which led to failure of a metal-on-metal total hip arthroplasty.
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ranking = 0.0013811899877195
keywords = lower
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3/50. Tumor-like tuberculosis of the sacrum.

    Isolated tuberculosis of the sacrum in a 43-year-old woman manifested as functional impairment of the right lower limb. Sacral tuberculosis is rare in patients with no history of tuberculosis. Another unusual feature was the tumor-like aspect of the lesion, with diffuse, ill-defined osteolysis of a large part of the sacrum and extension to the presacral soft tissues responsible for rectal displacement.
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ranking = 0.0013811899877195
keywords = lower
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4/50. Progressive erosive arthropathy with contractures, multicentric osteolysis-like changes, characteristic craniofacial appearance, and dermatological abnormalities: a new syndrome?

    We report a 27-year-old man with an apparently new syndromic form of progressive erosive arthropathy and contractures of small and large joints associated with mild epiphyseal changes, normal vertebrae, and generalized osteopenia. The patient had a characteristic craniofacial appearance, dermatological abnormalities, and normal intelligence. The head was large with frontal bossing. The face was elongated with malar hypoplasia, thin upper lip, prominent lower jaw, high arched palate, dental malocclusion, and prominent ears with absent ear lobules. Dermatological abnormalities included malar erythema and facial telangiectasia together with multiple nevi and lentigenes all over the body. Pseudorheumatoid arthropathy, spondyloarthropathy, and Borrone dermatocardioskeletal syndrome were considered in the differential diagnosis and were excluded. Also, no similar cases have been found in POSSUM or the london Dysmorphology databases.
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ranking = 0.039033402404198
keywords = jaw, lower
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5/50. eosinophilic granuloma as a form of inflammatory reaction. A case report.

    eosinophilic granuloma consists of the proliferation and/or accumulation of langerhans cells in the bones, generally of the cranium and face, as a uni- or multifocal cystic lesion. It is considered to be a localized chronic form of Langerhans cell disease. The most frequent oral location is the posterior part of the mandible, where the bone lesion often gives rise to lesions of the overlying soft tissues. We report a case showing bilateral involvement of the upper jaw and unilateral involvement of the mandible. The eosinophilic granulomas arose in association with odontogenic periapical infectious processes, suggesting that this disorder may be a form of inflammatory response.
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ranking = 1.0376522124165
keywords = mandible, jaw
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6/50. Anaesthesia of the right lower hemilip as a first manifestation of multiple myeloma. Presentation of a clinical case.

    multiple myeloma is a malignant proliferation of plasma cells. It may affect any of various bones, causing osteolytic lesions with a characteristic "punched out" radiographic appearance. The commonest symptom is bone pain. One of the most frequent locations is the mandible. Symptoms of multiple myeloma of the mandible include tumefaction, non-specific pain, tooth mobility and sometimes loss, and paraesthesia of the dental nerve. Here we report a case of multiple myeloma of the mandible which was unusual in that the presenting complaint was anaesthesia of the right lower hemilip.
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ranking = 1.5069059499386
keywords = mandible, lower
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7/50. The multicentric epitheloid hemangioendothelioma of bone: a case example and review of the literature.

    Epitheloid hemangioendothelioma of bone is a rare primary bone malignancy. diagnosis can be difficult for physicians who are not experienced with bone neoplasms. We also had difficulties in diagnosis and treatment in one of our patients with a multicentric epitheloid hemangioendothelioma involving the pelvis, left femur, and left tibia. We recommend a complete skeletal survey with magnetic resonance imaging because it can reveal previously undetected lesions on conventional radiographs. We performed an extraarticular resection of the hip joint including the spina iliaca anterior inferior, resection of the femur, and amputation of the lower leg. The femur was replaced by a modular endoprosthesis. The patient is provided with an above-knee prosthesis and is able to walk even longer distances with a cane 2 years after surgery. In our opinion it is necessary to perform a wide resection of this tumour in order to treat a patient with curative intention. Palliative radiotherapy should only be used for a non-resectable tumour or in metastatic disease. Chemotherapy is not a treatment option.
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ranking = 0.0013811899877195
keywords = lower
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8/50. An unusual form of actinomycosis of the mandible with a resultant gross sequester in a 4-year-old child: a case report.

    Mandibular osteomyelitis due to actinomyces group is considered rare in the pediatric population. The initial complaint of the 4-year-old child described here was increased swelling of his cheek and pain. The patient was managed successfully by surgical treatment with antibiotic therapy.
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ranking = 2
keywords = mandible
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9/50. Benign osteoblastoma of the mandible. A clinical-pathologic review and report of a case.

    Benign osteoblastoma is an uncommon, solitary, osteoid and bone-producing tumor which is characterized by prevalent active osteoblasts and rich vascularized delicate fibrous stroma, previously regarded as malignant. The term benign osteoblastoma was recently proposed by different authors to separate this lesion from other solitary benign bone tumors. It most often involves long bones and vertebral column and other bones, and also occurs in jaw bones. There is a close histopathologic similarity between benign osteoblastoma and osteoid osteoma; consequently, much debate about them exists. Benign osteoblastoma has a good prognosis and is best treated by curettage or conservative surgical excision. recurrence is rare. Because of its rarity in jaw bones, one case of benign osteoblastoma of the mandible is reported.
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ranking = 2.575304424833
keywords = mandible, jaw
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10/50. growth changes and orthodontic treatment in a patient with condylolysis.

    A patient with acquired bilateral degeneration of the mandibular condyles was treated orthodontically. The flattening of condyles and the shortening of the ramus began at adolescence. The facial profile changed to a convex type, with a marked mandibular retrognathia and severe Class II malocclusion. The cause seems to be due to a condylolysis of the mandible.
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ranking = 0.5
keywords = mandible
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