1/9. mumps virus neutralizing antibodies do not protect against reinfection with a heterologous mumps virus genotype.In April 1999, a previously healthy 22-year-old woman was taken ill with fever and bilateral swelling of the parotid glands. A chronic course of disease extending from April to December was found with swelling of the parotid glands, fatigue, low grade fever, episodes of tachycardia and nightswetting. mumps virus rna of genotype A character based on the SH (small hydrophobic) protein gene classification was demonstrated in three serum samples collected during the course of clinical disease. Different criteria for reinfection were fulfilled including demonstration of IgG antibodies by ELISA in a preinfection serum sample. The preinfection serum sample of the patient was able to efficiently neutralize the infectivity of a heterologous genotype D strain but was unable to neutralize the homologous genotype A virus. The findings in the present study may offer an explanation of a mechanism behind previously observed vaccine failures and the occurrence of reinfection with heterologous mumps virus strains.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
2/9. An adult case of mumps brainstem meningoencephalitis with a past measles-mumps-rubella (MMR) vaccination.Severe complications such as meningoencephalitis are quite rare in the setting of mumps infection. We report here on a 24-year-old soldier with a past history of MMR vaccination who was admitted because of aseptic meningitis. His mental status rapidly deteriorated and swelling of both parotid glands was observed. The MR findings revealed discrete lesions in the brainstem and thalamus. He barely recovered within 2 months. Among the adults with failure to acquire immunity despite MMR vaccination, institutional crowding can lead to cases of potentially fatal CNS complication such as mumps meningoencephalitis.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
3/9. mumps virus infection in adults: three cases of supraglottic edema.mumps virus infections primarily involve the parotid glands and most frequently affect school-aged children. We present three unusual adult cases of mumps with dyspnea secondary to severe swelling of the salivary glands and review previously reported cases in the literature. dyspnea developed progressively after the onset of salivary gland swelling. laryngoscopy revealed an advanced edematous change in the supraglottis obstructing the airway. In two cases, tracheotomy was needed because of rapid worsening of the supraglottic edema. Questioning regarding breathing problems and laryngoscopic examination is therefore recommended when one encounters a mumps case with combined parotid and salivary gland swelling.- - - - - - - - - - ranking = 2keywords = gland (Clic here for more details about this article) |
4/9. Down in the mumps.A 10-week-old female infant presented with a right-sided facial swelling without any constitutional symptoms. The swelling was nontender, nonfluctuant, with no erythema or induration. On the basis of the clinical picture, magnetic resonance imaging findings and serology, a diagnosis of unilateral mumps parotitis was made. The United Kingdom is currently experiencing a mumps epidemic with a 28-fold rise in the number of cases over the last 10 years. Infants are being increasingly affected. Mumps parotitis, which was previously unreported in infants, needs to be considered as part of the differential diagnosis when a small child presents with swelling of the parotid gland.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
5/9. Diagnosing salivary stones.Sialolithiasis, or the formation of sialoliths or salivary stones, typically occurs in the ducts of the submandibular and parotid glands of middle-aged adults. pain and swelling are often among the first signs and symptoms. Obstructive sialadentitis, epidemic parotitis (mumps) and salivary gland tumors, should all be included in the differential diagnosis for sialolithiasis.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
6/9. Presternal swelling in mumps.A case of presternal swelling associated with mumps is presented. presternal swelling occurs secondary to obstruction of the lymphatic drainage from the anterior-superior chest wall by the enlarged cervical salivary glands. The occurrence of this complication in mumps is discussed.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
7/9. Etiologic aspects and orthodontic treatment of unilateral localized arrested tooth-development combined with hearing loss.In this study a case has been presented involving localized, arrested maxillary tooth development, asymmetric maxillary development, and unilateral loss of hearing. No similar case seems to have been described before. The orthodontic treatment comprised extraction of four permanent tooth germs in the maxilla and autotransplantation of mandibular teeth, followed by the use of fixed orthodontic appliances and a one-unit bridge restoration. Etiologic aspects are discussed. It is suggested that a severe attack of mumps that involved massive swelling of the parotid glands immediately after chicken pox and measles at the age of 4 to 5 years, may have resulted in a neurologic reduction of hearing and arrested tooth development. The teeth in which root development in relation to mumps does not appear to have been reported previously, whereas hearing loss after mumps has been reported. In the search for verification of this possible connection, children with arrested tooth development should be examined for reduction of hearing, and children with hearing loss after mumps ought to have their dental development checked.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
8/9. herpes simplex encephalitis mimicking mumps.A 16-year-old male diabetic patient presented with bilateral salivary gland swellings followed by encephalitis. The EEG did not show the characteristic periodic lateralising epileptic discharges. Neuro-imaging disclosed compromise of temporal and frontal lobes as well as brain stem which correlated well with his clinical deterioration. serology and frontal brain biopsy were positive for herpes simplex virus while mumps titers were not significant. Despite delayed acyclovir therapy, the patient recovered enough to be discharged home with a permanent pseudobulbar palsy. herpes simplex encephalitis involving zones other than temporal lobes is exceptional. To our knowledge, there are no reported cases of pseudobulbar palsy as a sequelae of HSV encephalitis.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
9/9. Sudden total bilateral deafness due to asymptomatic mumps infection.Mumps is the most common cause of unilateral acquired sensorineural hearing loss in children. Although it usually affects the salivary glands. the inner ear may be involved. deafness is usually unilateral, sudden in onset, profound and permanent. Bilateral total sensorineural hearing loss had been rarely reported in English literature. We present a case of total deafness due to asymptomatic mumps infection.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |