1/22. Oral crohn disease: clinical characteristics and long-term follow-up of 9 cases.BACKGROUND: Oral localization of crohn disease is uncommon and must be differentiated from nonspecific lesions. Its natural course and its long-term prognosis are unknown. OBSERVATIONS: We studied 9 patients (8 male, 1 female; age range, 7-52 years; median age, 16 years) with crohn disease and specific oral lesions, including deep linear ulcers, pseudopolyps, and/or labial or buccal swelling and induration. The prevalence of such lesions was 0.5%. The median follow-up was 11 years. Oral localization developed before (n = 2), at the same time as (n = 2), or after (n = 5) the onset of the digestive disease. Noticeable associated localizations were observed in the anoperineum (n = 8) and the esophagus (n = 3). The median duration of the oral lesions was 4 years (range, 1-13 years), without necessary parallelism with the digestive localization. Five patients had complete healing after a median delay of 2 years. CONCLUSIONS: Oral localization of crohn disease is characterized by a marked male predominance, a young age at onset of crohn disease, and a very protracted course. The high prevalence of associated anal and esophageal involvement suggests that Crohn lesions have a particular trophicity for squamous cell epithelium.- - - - - - - - - - ranking = 1keywords = labial (Clic here for more details about this article) |
2/22. Ectopic erythema migrans in an adolescent with a skin disorder.Red and white circular lesions of the buccal and labial mucosa were observed in an adolescent. Periodically, these nontender patches would resolve and move to other oral sites. Detection of ectopic erythema migrans aided in the diagnosis of a bothersome skin condition.- - - - - - - - - - ranking = 1keywords = labial (Clic here for more details about this article) |
3/22. common variable immunodeficiency with unusual vegetative lesions of the tongue and labial mucosa: a case report.A case of common variable immunodeficiency with unusual vegetative lesions of the tongue and lower lip in a 28-year-old man is presented. The vegetative lesions developed over the preceding 10 months and clinically were suggestive of malignancy. The biopsy specimens showed no malignancy, and a bacterial culture of the tongue detected abundant staphylococcus aureus. Combined treatment with a corticosteroid antibiotic ointment and povidone iodine rinse produced remarkable resolution of the lesions. Laboratory examination showed markedly decreased levels of serum immunoglobulins. Intravenous gamma globulin replacement therapy resulted in good control of infection and disappearance of the lesions.- - - - - - - - - - ranking = 4keywords = labial (Clic here for more details about this article) |
4/22. Topical tacrolimus: a novel therapeutic intervention for recalcitrant labial pemphigus vulgaris.We report a case of a persistent lip ulcer in a patient with mucocutaneous pemphigus vulgaris, recalcitrant to various topical and systemic corticosteroids and immunosuppressants, which resolved following the administration of topical tacrolimus.- - - - - - - - - - ranking = 4keywords = labial (Clic here for more details about this article) |
5/22. A case of oral myiasis due to Chrysomya bezziana.Chrysomya bezziana is a causative agent of obligatory myiasis. We report the first case of human infestation of Chrysomya bezziana in hong kong in an 89-year-old woman who had previously had a stroke. One day after hospital admission for fever, a small fissure at the labial gingiva of the upper incisors and several ulcerative lesions at the hard palate were noticed during routine mouth care. A live maggot was seen protruding from the small fissure. In the following few days, a total of seven maggots were removed by forceps. Urgent computed tomography and magnetic resonance imaging of the oral cavity showed an ulcerative soft-tissue lesion over the anterior palate, with a fistula communicating to the labial gingiva. The tissue loss was limited to the bony margin of the hard palate. The infestation was managed by manual removal of maggots and surgical debridement. Medical personnel taking care of old or debilitated patients need to bear in mind the possibility of Chrysomya bezziana infestation to be able to make a prompt diagnosis and implement relevant intervention to prevent extensive tissue destruction.- - - - - - - - - - ranking = 2keywords = labial (Clic here for more details about this article) |
6/22. Sebaceous carcinoma of the oral mucosa: case report and review of the literature.Fordyce granules are found in the oral mucosa of up to 80% of adults. However, primary malignant sebaceous tumors of the oral mucosa are exceedingly rare. To our knowledge, only 5 examples of intraoral sebaceous carcinoma have been reported in the literature. This report describes a primary sebaceous carcinoma of the labial mucosa that arose in an area containing numerous Fordyce granules. A brief review of the clinical and histopathologic features of sebaceous carcinoma is also presented.- - - - - - - - - - ranking = 1keywords = labial (Clic here for more details about this article) |
7/22. Oral lichenoid eruption secondary to imatinib (Glivec).BACKGROUND: Oral lichenoid drug eruption (OLE) is a self-restricted inflammatory condition usually secondary to a variety of drugs and dental materials (mercury, gold), and rarely to immunomodulators and new antineoplastic agents such as imatinib mesylate (Glivec). OLE clinical features are reminiscent of lichen planus and include symmetric and asymptomatic, erythematous, reticulated and painful ulcerated plaques. Histological examination reveals perivascular lymphocytic infiltrate and the presence of eosinophils that obscures the dermal-epidermal junction, with acanthosis and mild hyperkeratosis. methods: A 62-year-old man was treated with Glivec for metastatic gastrointestinal stromal tumour (GIST). RESULTS: The patient presented with grey-violaceous plaques on both cheek mucosal surfaces and the lateral sides of the tongue and labial mucosa, with a reticular pattern resembling oral lichen planus. These lesions appeared approximately 1 year after therapy and partially subsided in about 10 weeks, to clear after topical corticosteroids and oral omeprazole. The diagnosis of OLE induced by imatinib was confirmed by histological biopsy evaluation; immunohistochemical analysis revealed intense immunoreactivity with only cytokeratins 5/6 and 14 in the epithelium of affected mucosa. All laboratory investigations proved asiderotic anaemia but excluded infectious causes. CONCLUSION: It is believed that this patient developed imatinib-induced OLE; this relationship with therapy rather than the underlying disease rules out a paraneoplastic reaction, and negative immunofluorescence excluded autoimmune dermatosis. In addition, we propose that these lesions are correlated with abnormal expression of some cytokeratins directly caused by this drug.- - - - - - - - - - ranking = 1keywords = labial (Clic here for more details about this article) |
8/22. diagnosis of systemic sarcoidosis prompted by orofacial manifestations: a review of the literature.BACKGROUND: sarcoidosis is a multifactorial systemic inflammatory disorder of unknown origin characterized by many potential signs and symptoms, as well as by the presence of noncaseating granulomas in the organs involved. sarcoidosis also may manifest in the oral and maxillofacial region. CASE DESCRIPTION: The authors describe a patient with xerostomia, dysgeusia, oral burning, xerophthalmia and bilateral parotid enlargement. She was diagnosed as having systemic sarcoidosis on the basis of the histologic findings of a biopsy of the labial minor salivary gland, as well as subsequent diagnostic evalutons. CONCLUSION AND CLINICAL IMPLICATIONS: Enlargement of major salivary glands may be the first sign of sarcoidosis in a patient with few other symptoms or clinical findings suggestive of the disease. This case emphasizes the importance of including sarcoidosis in the differential diagnosis of bilateral parotid swelling associated with xerostomia. It also highlights the dentist's potential role in the diagnosis and dental treatment of patients with systemic sarcoidosis.- - - - - - - - - - ranking = 1keywords = labial (Clic here for more details about this article) |
9/22. Foreign body reaction due to skin filler: a case report.Aquamid represents a new generation of soft-tissue fillers for aesthetic facial correction and reconstruction due to its reduced quantity of particles (2.5% of polyacrylamide) and high concentration of water (97.5%). It is a biocompatible, atoxic, homogeneous, and stable product. Additionally, it has good viscosity and elasticity, and it is very simple to use. Although reported in less than 1% of the cases, adverse effects such as pain, swelling, and erythema may occur, which may be the result of inappropriate injection procedure. This article reports the first case of an intraoral foreign body reaction resulting from Aquamid application in the nasolabial fold. Possible causes for this reaction, the chemical composition of the product, and the histopathologic aspects are discussed.- - - - - - - - - - ranking = 1keywords = labial (Clic here for more details about this article) |
10/22. Intravascular papillary endothelial hyperplasia in the oral mucosa.An intraluminal reactive hyperplastic lesion from the lower labial mucosa of an adult male patient is described. It has been termed intravascular papillary endothelial hyperplasia and may have arisen in an organizing thrombosed vein. The importance of distinguishing it from a malignant vascular neoplasm is stressed, and the differential diagnosis is discussed.- - - - - - - - - - ranking = 1keywords = labial (Clic here for more details about this article) |
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