11/1591. Primary pulmonary Hodgkin's disease: CT findings in three patients.The computed tomography (CT) findings in three patients with primary pulmonary Hodgkin's disease are reported. Two patients had unilateral upper lobe cavitated masses and one patient had bilateral lower lobe nodules.- - - - - - - - - - ranking = 1keywords = upper (Clic here for more details about this article) |
12/1591. Pulmonary intravascular lymphomatosis: presentation with dyspnea and air trapping.Intravascular lymphomatosis (IVL) is a rare lymphoid neoplasm that is typically of B-cell lineage and characterized by proliferation of malignant cells within small arterioles, capillaries, and venules. We report a patient with pulmonary IVL who presented clinically with progressive dyspnea, fever, and a dry cough. Pulmonary function tests revealed a marked decrease in diffusion capacity with airflow obstruction and severe air trapping. High-resolution CT (HRCT) of the chest with inspiratory and expiratory images revealed mosaic attenuation consistent with air trapping. Transbronchial biopsies revealed the diagnosis of IVL with capillary expansion in the alveolar and peribronchiolar interstitial tissue. IVL should be considered in the differential diagnosis of a patient with an interstitial lung disease, air trapping on pulmonary function tests, and mosaic attenuation on HRCT. Transbronchial biopsies may be the initial diagnostic procedure of choice.- - - - - - - - - - ranking = 7.2439481320432keywords = chest (Clic here for more details about this article) |
13/1591. Pulmonary small cell carcinoma associated with sarcoid reactions: report of a case.A 45-year-old male was admitted to our hospital for investigation of a nodular shadow in segment 5 of the right lung on a chest computed tomogram. A right middle lobectomy with mediastinal lymph node dissection was performed under a diagnosis of lung cancer, and histologic examination confirmed small cell carcinoma. There were sarcoid reactions in the resected lymph nodes and the lung parenchyma, but no signs of systemic sarcoidosis were evident. Sarcoid reactions are rarely observed in the regional lymph nodes draining malignant tumors. Moreover, while they are most common in squamous cell carcinoma of the lung, they extremely rare in small cell carcinoma. To our knowledge, this is only the third report of this unusual entity in the English and Japanese literature.- - - - - - - - - - ranking = 7.2439481320432keywords = chest (Clic here for more details about this article) |
14/1591. pulmonary blastoma: report of a case.We herein describe a 27-year-old male presenting with a pulmonary blastoma. The patient was admitted to our hospital with the chief complaints of fever and left back pain. Chest roentgenograms showed a tumor measuring 10 cm in diameter in a lower lobe of the left lung. Computed tomography and magnetic resonance imaging revealed a well demarcated and heterogeneously enhanced tumor. Although a histological diagnosis could not be obtained by a transbronchial biopsy, image analyses led us to suspect it to be malignant. The patient underwent a left lower lobectomy with lymph node dissection. A histopathological examination revealed the tumor to be a biphasic type of pulmonary blastoma. Because of the rapid progress of the tumor and the difficulty in making a preoperative diagnosis in such cases, an immediate surgical resection is therefore recommended in cases with even the slightest suspicion of malignancy.- - - - - - - - - - ranking = 0.55618822098616keywords = back pain, back (Clic here for more details about this article) |
15/1591. Angiosarcoma of the chest wall.Angiosarcoma is a rare and highly malignant tumor of vascular origin. The causative factors include trauma, radiation, foreign bodies, thorium dioxide, and viral infections. We report a case of angiosarcoma occurring in a thoracotomy incision 17 years after operation for stage I lung cancer.- - - - - - - - - - ranking = 28.975792528173keywords = chest (Clic here for more details about this article) |
16/1591. Primary synovial sarcoma of the lung: report of two cases confirmed by molecular detection of SYT-SSX fusion gene transcripts.AIMS: Primary pulmonary sarcoma is rare, and frequently creates diagnostic challenges. We describe two cases of primary pulmonary spindle cell sarcoma in which a molecular approach using archival paraffin-embedded tissue was proved to aid diagnosis. methods AND RESULTS: Both patients had huge masses replacing the upper and middle lobes of the lung, respectively, without any primary extrapulmonary neoplastic lesions. Microscopically, the lesions showed a solid hypercellular nodular or lobular growth of atypical short spindle cells in variably intersecting fascicles or in a haphazard fashion, together with focal areas displaying a prominent haemangiopericytoma-like pattern. Immunohistochemically, a small number of the tumour cells were positive for epithelial markers such as cytokeratin and epithelial membrane antigen. In both cases, a reverse transcription-polymerase chain reaction using rna extracted from formalin-fixed, paraffin-embedded tissues detected SYT-SSX fusion gene transcripts, which are characteristic of synovial sarcoma. CONCLUSION: On the basis of the morphological and molecular findings, these tumours are considered to be rare examples of monophasic synovial sarcoma of the lung. Our molecular assay detecting the SYT-SSX fusion transcripts is useful for the final diagnosis of synovial sarcoma arising at such an unusual anatomical site.- - - - - - - - - - ranking = 1keywords = upper (Clic here for more details about this article) |
17/1591. Spontaneous regression of large-cell carcinoma of the lung--a rare observation in clinical practice.Spontaneous regression of non-small-cell lung carcinoma is extremely rare and there are few documented cases. We report a 59-year-old man with a right upper lobe tumour which showed progressive regression while hilar adenopathy appeared 2 months after the initial tumour detection. At operation, only scar tissue was found in the lung but a hilar lymph node contained large-cell undifferentiated carcinoma. This report indicates that a decrease in size of a pulmonary mass does not exclude the diagnosis of carcinoma and that metastatic disease can occur even if the primary tumour regresses.- - - - - - - - - - ranking = 1keywords = upper (Clic here for more details about this article) |
18/1591. October 1998--61 year old male with brain tumor and oral, lung, and palpebral masses.In Jan. 97 a gliosarcoma was diagnosed in a 61-year- old man after a 6-month history with neurological deficits. A total physical examination, laboratory tests, chest x-ray and abdominal ultrasound scanning revealed no gross abnormalities. Surgery was followed by brain radiation therapy and 6 months later there were metastases to the oral cavity, right palpebra and both lungs. The histological findings of the oral and palpebral metastases revealed only the sarcomatous component. We are aware of 15 cases of gliosarcoma with extraneural metastases, and in 4 of these, the metastases contained only the sarcomatous component. We believe that our case represents the fifth case of pure sarcomatous metastases.- - - - - - - - - - ranking = 7.2439481320432keywords = chest (Clic here for more details about this article) |
19/1591. Sternothoracotomy for combined coronary artery bypass grafting and left upper lobectomy in a patient with low-lying tracheostoma.A 64-year-old man had a low-lying tracheostoma and presented with unstable angina and a mass in the pulmonary left upper lobe. Simultaneous coronary revascularization and resection of the lung neoplasm were completed through a sternothoracotomy (clam-shell) incision. The advantages of this approach include excellent exposure to the mediastinum and the lung fields, and the option of using both internal thoracic arteries for bypass grafting.- - - - - - - - - - ranking = 5keywords = upper (Clic here for more details about this article) |
20/1591. Chest wall implanted reservoir for bronchial arterial infusion of antineoplastic agents in high-aged lung cancer patients.Arterial infusion therapy has been actively adopted to treat cancerous lesions in various clinical fields. In the past, a one-shot infusion via the bronchial artery has been used in lung cancer patients. In order to improve the patient's quality of life and enhance his/her response to chemotherapy, we have developed a chest wall implanted reservoir system for arterial infusion of antineoplastic agents via the bronchial artery. A slender catheter was inserted in a bronchial artery through the left subclavian artery (first case through the right femoral artery) in five patients over 75 years old with lung cancer. The reservoir was embedded in the chest wall (first case in the femoral region) and the antineoplastic agents were infused repeatedly on an outpatient basis. In two patients, accumulation of 99mTc-MAA in the primary lung tumor was confirmed by RI (radio-isotope) angiography. All patients could lead an active daily life during treatment. The results indicate that satisfactory therapeutic effects as well as an improvement of the patient's quality of life can be expected with this treatment modality, especially in case of the chest-wall reservoir with an indwelling catheter in the left subclavian artery.- - - - - - - - - - ranking = 21.73184439613keywords = chest (Clic here for more details about this article) |
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