1/5. Metastatic malignant ameloblastoma of the kidneys.ameloblastoma is an uncommon disease in the urological field. The resulting tumors or cysts are of odontogenic epithelial origin, are usually benign in nature and rarely metastasize to distant organs. We describe a case of metastatic ameloblastic carcinoma in both kidneys of a 38-year-old Japanese man, who had a history of malignant ameloblastoma and was referred to us for evaluation because of gross hematuria and left flank pain. Computed tomography showed irregular cystic masses in both kidneys. After we confirmed that the primary lesion and the lung metastatic lesion had not recurred, we treated the patient surgically. Approximately 4 months postoperatively the patient suffered a local recurrence of tumors that was very invasive and aggressive. The patient died 2 months later and the autopsy showed local metastasis only, without any metastatic lesion in the lungs or other organs. The present case showed that malignant ameloblastoma is highly aggressive, and in the case of metastases the prognosis is usually extremely poor.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
2/5. The histochemical nature of homogeneous amorphous materials in odontogenic epithelial tumors.The homogeneous acellular materials in the adenomatoid odontogenic tumor, calcifying epithelial odontogenic tumor, and calcifying odontogenic cyst were examined histochemically for specific staining of amino acids and protein groups. These materials gave a positive reaction for periodic acid-Sciff (PAS), alloxan-Schiff, and dinitrofluorobenzene-H-acid and low reaction for alcian blue, dimethylaminobenzaldehyde (method for tryptophan) and the Morel-Sisley diazotization method. They appear to have approximately the same composition as enamel matrix and are not amyloid in nature. The materials may be synthesized products from neoplastic epithelium that may originate from enamel organs.- - - - - - - - - - ranking = 5keywords = nature (Clic here for more details about this article) |
3/5. Central odontogenic fibroma: review of literature and report of cases.The features of two cases of central odontogenic fibroma are presented and the literature is reviewed. Controversial issues surrounding this neoplasm are discussed. The cases presented here include the oldest reported patient with this neoplasm and the first instance of its occurrence at a maxillary site. Treatment and follow-up information emphasize the benign nature and slow growth of these lesions.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
4/5. Familial florid cemento-osseous dysplasia--a case report and review of the literature.Cemento-osseous dysplasia is a fairly common lesion of the jaws originating from the elements of the periodontal ligament. Most lesions do not have a hereditary basis, however a few familial cases have been documented. This is the first report of the florid form of cemento-osseous dysplasia in an African family. The mother, son and one daughter exhibited multiple sclerotic cemental masses of the jaws with large tumour-like swellings in the symphyseal area of the mandible. In the case of the mother the lesions had become infected. The familial form of cemento-osseous dysplasia differs from the non-hereditary type in that the lesions present in children, all cases are florid in nature, there is no predilection for black females, the rate of growth appears to be more rapid and the symphyseal area of the mandible is most severely affected. The mode of transmission appears to be autosomal dominant with variable phenotypic expression.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
5/5. recurrence of unicystic ameloblastoma: a case report and review of the literature.Unicystic ameloblastoma is believed to be less aggressive and responds more favorably to conservative surgery than the solid or multicystic ameloblastomas. We report a case of unicystic ameloblastoma that was initially treated by marsupialization and later by enucleation under suspicion of a dentigerous cyst. The neoplastic nature of the lesion became evident only when the enucleated material was available for histologic examination. Apart from an ameloblastomatous epithelial lining and luminal tumor nodules, the cystic tumor contained numerous tumor islands within its fibrous capsule. The lesion recurred 8 years after the enucleation. This case supports the view that the presence of tumor islands in the fibrous capsule may indicate a high risk of recurrence for unicystic ameloblastomas. Relevant diagnostic problems and choice of treatment are presented along with a review of the literature.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |