1/16. angiography in the diagnosis and therapy of hemorrhage from the large bowel.angiography has added a new dimension to the management of hemorrhage from the large bowel. In patients with diverticular hemorrhage, mesenteric angiography not only localizes the bleeding site but, in addition, the bleeding can be acutely controlled with intraarterial infusion of vasopressin, making an emergency colectomy unnecessary. Similarly in patients bleeding from inflammatory bowel disease or in patients with post-operative hemorrhage, angiography provides information about the nature of the lesion and selective arterial infusions of vasopressin can control the bleeding. At times intestinal varices have angiographically been demonstrated as a potential source of rectal hemorrhage while in patients with unexplained lower gastrointestinal bleeding and repeatedly negative barium and endoscopic examinations, angiography has been valuable for the diagnosis of angiodysplasia of the colon.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
2/16. The radiological demonstraction of colorectal polyps undetected by endoscopy.In a consecutive series of 800 routine double contrast studies of the colon, 119 polyps were diagnosed radiologically in 78 patients. follow-up studies were available in 46 patients with 72 polyps. Ultimately, 56 of these polyps were confirmed (55 by endoscopy and 1 by repeat radiology). Six of these polyps had been missed on the initial endoscopic examination. The missed polyps are usually located in the rectum behind a valve of Houston or in any area of the colon where there is sharp angulation. Radiologists and endoscopists should be aware of these as potential endoscopic blind spots. These cases illustrate the importance of higg quality radiological study of the colon and the complementary nature of radiology and endoscopy in the detection of colorectal polyps.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
3/16. Colorectal polyposis with mixed juvenile and adenomatous patterns.An unusual form of colorectal polyposis is described displaying juvenile, adenomatous and mixed patterns in a 17-year-old girl. Although juvenile polyposis is generally considered to be non-neoplastic in nature, in both the present and in other case reports histological findings support a neoplastic nature. Since an increase in the incidence of large bowel carcinomas has been found in subjects with a previous diagnosis of juvenile polyposis, these patients should be considered to be at risk, and submitted to follow up.- - - - - - - - - - ranking = 2keywords = nature (Clic here for more details about this article) |
4/16. Primary rectal lymphoma and malignant lymphomatous polyposis. Two cases illustrating current methods in diagnosis and management.Two cases of colorectal lymphoma are presented. Preoperative histologic diagnosis is difficult and examination of the fresh specimen using immunocytochemical and gene rearrangement techniques are necessary to establish the precise nature of the lesion. Surgical excision is the mainstay of treatment for localized lymphoma of the colorectum and chemotherapy for malignant lymphomatous polyposis.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
5/16. Lymphoid polyps of the rectum.In children lymphoid polyps of the rectum are uncommon benign lesions with a good prognosis following local treatment. We report a girl in whom a cluster of lymphoid polyps occurred 9 months following removal of a single lymphoid polyp. All of the polyps, including the original lesion, displayed a monoclonal nature on immunocytochemical examination.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
6/16. Polypoid gastric heterotopy of the small intestine in a patient with primary hyperparathyroidism and alpha-1-antitrypsin deficiency belonging to a MEA-family. With particular reference to the ultrastructure of the epithelial cells.A patient with a solitary polypoid gastric heterotopy in the jejunum and severe bleeding as a complication is described. Previous reports on this rare disorder and the conditions of its development are discussed. The patient belongs to a family with multiple endocrine adenomatosis (MEA), some members of which had an alpha-1-antitrypsin deficiency. The association between the familial disease and the gastric heterotopy in this case might be another argument for the assumed congenital nature of the latter. The polyp was studied by means of light and electron microscopy. It was mostly lined by fundic mucosa and only partially by antral mucosa. Focal foveolar hyperplasia, cysts and lymphoplasmacellular infiltration of the mucosa are regarded as secondary tissue alteration. Parietal cells, chief and endocrine cells were identified. The parietal cells were in the nonsecreting state and appeared in two distinct forms which are described in detail.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
7/16. Adrenal adenomas and adrenal carcinomas in association with hereditary adenomatosis of the colon and rectum.Hereditary adenomatosis of the colon and rectum (HACR) is associated with a wide variety of extracolonic manifestations. Two cases of neoplasia involving the adrenal gland are reported, one adenoma and one carcinoma. The literature relating these lesions to HACR and other syndromes of malignant and nonmalignant growth disturbance is reviewed. The increasing list of the extracolonic manifestations associated with HACR emphasizes the generalized nature of the growth disorder of this disease. An increased awareness of these lesions is important, as many patients with HACR now live longer by avoiding death from colorectal carcinomas due to the increasing usage of prophylactic colectomy.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
8/16. Colon and anorectal neoplasms in a tropical African population.At the University College Hospital, Ibadan, nigeria, over a 30-month period (January 1975 to June 1977) more than 29 cases were fully studied. Nine patients presented with acute large bowel obstruction. In five cases, colonic neoplasms were palpated abdominally before surgery, and four of the patients were initially being treated for "hemorrhoids". All the patients presented at late stages. There was neither socio-economic nor sexual bias in this affliction. Sixty-nine percent of all the tumors occurred in the anorectal area well within the reach of the index finger, and 27.5% occurred in the right colon. Differential diagnosis included ameboma, rectal schistosomiasis, rectal tubercolosis, anal fistula and adult chronic intermittent intussusception. The treatment administered depended on the nature, location and stage of the disease. There was a case of metastatic squamous cell carcinoma of the hepatic flexure causing obstruction. The metastasis was from carcinoma of the cervix which had been treated with cesium insertions about three years previously. It is now known that colon and anorectal neoplasms, once regarded as rare among Africans living in tropical africa, is not that rare. With the Africans boycotting native "doctors" in favor of medical institutions, many of the diseases once thought to be rare in Africans will unfortunately become less rare.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
9/16. Complete remission in Cronkhite-canada syndrome.A case of Cronkhite-canada syndrome, where there was complete remission confirmed by radiology, endoscopy, and histology, is reported. On presentation, there was generalized gastrointestinal polyposis, hypoalbuminemia, skin pigmentation, onycho-dystrophy, and alopecia. enteral nutrition alone was administered for 10 wk, with resolution of the ectodermal features and disappearance of the polyps within 4 mo of commencement of the treatment. This report of complete remission supports the generally accepted nonneoplastic and essentially inflammatory nature of the polyps in Cronkhite-canada syndrome. Consideration needs to be given to nutritional deficiency as a cause of the syndrome.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
10/16. Inflammatory fibroid polyp of the colon simulating malignancy.The authors report an inflammatory fibroid polyp of the colon which simulated a tumor on the air-contrast barium-enema examination. Histological evaluation revealed the inflammatory nature of the polyp. These rare lesions can be radiographically indistinguishable from primary colon carcinoma.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
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