1/12. Unusual cardiac tumour with perivascular myoid differentiation: a case report.A previously healthy 70 year old woman was admitted for fatigue and dyspnoea on exertion and cough. A two dimensional echocardiography revealed a mass in the right atrium, which obstructed filling and infiltrated the cardiac chamber wall. Postsurgical histological examination revealed an unusual tumour with prevalent myoid glomangiopericytoma-type and haemangiopericytoma-like patterns. mitosis and necrosis were absent. A computed tomography scan excluded the presence of metastasis to distant organs or, conversely, metastatic involvement of the heart. Therefore, a diagnosis of tumour with perivascular myoid differentiation was made. This new entity, recently described in soft tissues, can easily recur. Its recognition helps to differentiate from metastasis and other primitive cardiac tumours sharing some morphological features but a different clinical behaviour, with consequent improvement to the management of patient care.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
2/12. Haemangiopericytoma of the maxillary gingiva: report of a case.AIM: Haemangiopericytoma (HPC) represents approximately 3% of all tumours in the head and neck. This tumour is a soft tissue tumour derived from mesenchymal cells with pericytic differentiation. We present the clinicopathological findings of a case. MATERIALS AND methods: A 69-year-old man was referred to our Department for a mass located on the right pre-molar maxillary gingiva; this mass caused problems during chewing, but was otherwise asymptomatic. RESULTS: Clinical examination revealed a nodular, pink lesion, 3.5 cm in diameter, which was lined with normal mucosa. The lesion was mobile in relation to the deep and superficial tissues. Microscopic analysis of the neoplasm showed a vascular rich pattern, constituted by vessels covered with flat endothelium and surrounded by abundant spindly cells. On the basis of these histological and immunohistochemical findings, the final diagnosis was HPC. CONCLUSIONS: HPC is an uncommon vascular tumour for which the biological behaviour is difficult to predict. In our patient, no recurrences or distant metastases were present at a 4 years follow-up.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
3/12. A rare case of solitary fibrous tumour of the pre-sacral space: morphological and immunohistochemical features.A 28-year-old woman presented with abdominal pain. Ultrasonograhic examination showed a pre-sacral mass, with complex structure and well delimitated cystss with thick walls. The resected specimen was 7.5 x 6 x 4 cm in size, well circumscribed and yellow in colour, with cysstic change containing mucoid-like material. Histologically, the lesion was composed of spindle cells with high cellularity and rich vascularization with a haemangiopericytoma-like pattern. The diagnosis of solitary fibrous tumour (SFT) was made. The differential diagnosis for SFT of the pre-sacral spaace involves haemangiopericytoma, GIST, malignant mesothelioma, synovial sarcoma, leiomyomatous tumours and granulosa cell tumour. Immunohistochemical studies revealed reactivity for CD34, CD99 and Bcl-2, but no staining for desmin, inhibin, c-kit, EMA, CK, SMA, S-100 and CD31, confirming a diagnosis of SFT. Although SFT is usually associated with a favourable prognosis, close follow-up is recommended because of the limited information on its long-term behaviour.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
4/12. Haemangiopericytoma: problems in diagnosis and management.Three cases of haemangiopericytoma with diverse modes of presentation are reported. The difficulties with clinical diagnosis are emphasized. There is no consensus on the best mode of treatment, and we have chosen radical surgical excision in the first instance, but have not hesitated to employ radiotherapy or chemotherapy as adjunctive treatment if the need has arisen. The clinical behaviour of this tumour is unpredictable; therefore the prognosis for life must remain uncertain.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
5/12. Haemangiopericytoma of the lacrimal sac: a case report.A primary haemangiopericytoma of the lacrimal sac in a 45-year-old male is reported. The neoplasm, highly unusual in this location, recurred twice before being correctly identified. Total excision with surrounding tissue appears to be the treatment of choice for this tumour, the behaviour of which is often unpredictable.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
6/12. Primary malignant haemangiopericytoma of the larynx (a case report with autopsy).This is a report of an exceptional case of haemangiopericytoma of the larynx, which occurred in a 50-year-old male patient. Histological examination of biopsy fragments allowed us to make the correct diagnosis, later confirmed at autopsy. From a comprehensive review of the world literature on haemangiopericytomas, it appears that cases of indisputable well-documented laryngeal occurrence of the neoplasm amount to two only, including the present case. The morphological pattern, histogenesis, biological behaviour and therapy of the tumour, as well as differential diagnosis from other lesions, are discussed.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
7/12. Haemangiopericytoma.Three cases of orbital haemangiopericytoma are presented. In one the tumour recurred after 22 years and in another after 4 months. Metastasis to the breast, which occurred in the third case, is probably the first to be reported. The management of the cases is discussed. The clinical importance of the haemangiopericytoma lies in its potentially malignant behaviour.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
8/12. hemangiopericytoma: case reports.The authors' experience with two recent cases and their review of the literature suggest that the behaviour of hemangiopericytoma is unpredictable and that wide surgical excision is the treatment of choice because of the potential for malignant change.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
9/12. Haemangiopericytoma of the parotid gland. Report of a case and review of the literature.A primary malignant haemangiopericytoma of the parotid gland is reported. Microscopically the tumour showed two different types of area: in the first a histologically benign haemangiopericytoma was present, in the second, separated from the former by a clear-cut border, the structure was that of a histologically malignant haemangiopericytoma which subsequently metastasized and killed the patient. The report stresses the great rarity of this neoplasm in the parotid gland and discusses the problem of the behaviour of haemangiopericytomas.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
10/12. Haemangiopericytoma of the floor of the mouth. A case report.Haemangiopericytoma of the floor of the mouth with metastases to the lumbar spine in a 23-year-old black woman is described. She represents the 36th patient with oral cavity haemangiopericytoma and the 4th with a floor of mouth lesion. The aggressive behaviour of haemangiopericytoma and its resistance to all forms of recommended treatment was shown in this patient.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
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