11/22. noonan syndrome with giant cell lesions.noonan syndrome is characterised by short stature, unusual facies, congenital heart disease, chest deformity and mild mental retardation. It may be sporadic or inherited as an autosomal dominant trait and occurs between one in 1000-2500. cherubism is a giant cell lesion of the jaws thought to be transmitted as an autosomal dominant trait. It is usually recognised by age two to four years, follows a variable course, and is not known to be related to other genetic disorders. The purpose of this article is to report a case of multiple giant cell lesions of the mandible that occurred in a patient with phenotypic features of noonan syndrome. The emerging relationship between these cherubism-like findings and noonan syndrome will be discussed.- - - - - - - - - - ranking = 1keywords = mandible, jaw (Clic here for more details about this article) |
12/22. Giant cell tumours of the maxilla and tibia presenting concurrently as an initial manifestation of primary parathyroid adenoma.A 14 years female of Afghan origin reported with maxillofacial and tibia growths causing progressive deformities since nine months, both were giant cell tumours on histopathology. serum calcium was normal, but the parathyroid hormone was exaggerated (678 pg/ml). Ultrasound indicated and Tc-99m Setamibi scan confirmed a left lower parathyroid lesion. A 4cm length mass was identified, removed and proved to be a parathyroid adenoma. Two weeks later a subtotal maxillectomy and six weeks later anterior wedge osteotomy of the tibia were carried out. serum parathyroid hormone level normalized.- - - - - - - - - - ranking = 0.00583733651822keywords = lower (Clic here for more details about this article) |
13/22. Scanning electron microscopic observation of the brown tumor of the head of mandible.Brown tumors are tumor-like, expansile osteolytic lesions of bone which are seen in both primary and secondary hyperparathyroidism. They generally resolve after surgical treatment of the parathyroid adenoma. Here, we report a case of brown tumor of the mandible of a cadaver with its scanning electron microscopic observation and review of literature.- - - - - - - - - - ranking = 4.6837455770667keywords = mandible (Clic here for more details about this article) |
14/22. An unusual presentation of giant cell tumour (osteoclastoma).The number of well-documented true giant cell tumours arising in any of the craniofacial bones is small, but they do exist. A 19 year old female, Ms. KS, presented with complain of progressive enlargement of facial bones especially jaw bones, then orbit symmetrically since the age of 7. There was bilateral gross enlargement of mandible, maxilla, orbital walls, causing displacement of eye medially and upwards. The visual acuity of both eyes were 6/36 and 6/18 with best correction. Extra ocular movements were restricted because of bony growth and conjunctiva over inferior fornix were keratinized due to exposure. Fine needle aspiration (FNAC) from the side of bony growth showed plenty of osteoclasts with multinucleated giant cells. The level of serum alkaline phosphatase were highly increased. She underwent orbitotomy and a part of tissue was sent for biopsy which revealed multiples of mononucleargiant cells and tumour cells.- - - - - - - - - - ranking = 1keywords = mandible, jaw (Clic here for more details about this article) |
15/22. Use of short implants for functional restoration of the mandible after giant cell tumor removal. Case report.The giant cell tumor of the jaws is a rare benign lesion, it has a slow and progressive evolution and it is locally aggressive. Its etiopathogenesis is unknown, it is most common in the mandible and it is often asymptomatic but pain arises from palpation of the area. diagnosis is made by radiological and histological examination and surgical treatment is necessary. The clinical case of a 28-year-old man affected by a giant cell tumor of the mandible with an aggressive clinical and radiographical behaviour is reported. The patient showed a jaw swelling covered by hyperemic fibro-mucous tissue from tooth 4.6 to 3.4, absence of cortical bone and mobility of teeth. He also reported lip anesthesia. The giant cell tumor diagnosis was made with orthopantomography (OPT), computed tomography (CT) and needle biopsy. The lesion was surgically removed and histological examination confirmed the diagnosis. In spite of the wide loss of bony substance after surgery, the patient was provided with an implant supported fixed prosthesis without previous bone graft. In this case short implants allowed the prosthetic rehabilitation of a mandible with severe ''resorption'' due to surgical removal of a tumor. Implants were placed in the residual bone volume and successfully used to support a fixed prosthesis. The final result is optimal as is the quality of life of the young patient.- - - - - - - - - - ranking = 6.6837455770667keywords = mandible, jaw (Clic here for more details about this article) |
16/22. Giant cell tumour (central giant cell lesion) of the maxilla.The giant cell tumour (GCT) is a benign, locally invasive lesion that accounts for about 20% of benign bone tumours. Approximately 2% of all GCTs arise in the head and neck region. Giant cell lesions in the craniofacial skeleton other than the jaws are uncommon; the majority of them occur in the sphenoid, ethmoid and temporal bones. GCT of the maxilla has seldom been described. We present the case of an 83-year-old patient with an advanced GCT of the left maxilla who underwent en bloc resection through maxillectomy. Reconstruction of the orbitary frame and maxilla was performed with autologous calvaria and a temporalis muscle pedicled flap. Our successful maxillary reconstruction based on the association between autologous calvarial bone sticks bent with titanium miniplates and a temporalis muscle pedicled flap allowed the involvement of only one donor area for both hard and soft tissues. At 1-year follow-up, our patient showed no evidence of recurrent GCT, with satisfactory aesthetic results.- - - - - - - - - - ranking = 0.063250884586664keywords = jaw (Clic here for more details about this article) |
17/22. Brown tumor of the mandible associated with secondary hyperparathyroidism: a case report and review of the literature.Brown tumors are rare lesions that can develop in persistent cases of hyperparathyroidism (HPT). Therefore, identification of these lesions by diagnostic imaging is important during the follow-up of patients with HPT. This report describes a 45-year-old woman who developed HPT-induced brown tumors that appeared initially as an oral lesion. The diagnosis, treatment, and control of the disease--as well as the histopathological characteristics--are emphasized.- - - - - - - - - - ranking = 3.7469964616533keywords = mandible (Clic here for more details about this article) |
18/22. Giant cell tumor (osteoclastoma) of the mandible: a diagnostic dilemma and a therapeutic challenge.A recurrent giant cell lesion of bone 4.5 years after initial curettage from the mandibular body is described in a 40-year-old premenopausal female patient. Giant cell tumor is exceedingly rare in this location and histologically may be indistinguishable from giant cell reparative granuloma. The treatment rationale for this particular patient was extrapolated from the treatment of giant cell tumor in other more commonly involved bones. En bloc resection is indicated irrespective of the grade or stage of the tumor, provided satisfactory reconstruction can be achieved. The morbidity from tumor treatment should never, in any case, exceed the morbidity from the tumor itself.- - - - - - - - - - ranking = 3.7469964616533keywords = mandible (Clic here for more details about this article) |
19/22. Brown tumor of the mandible.Brown tumor is a focal lesion differentiated from other giant-cell tumors by the presence of hyperparathyroidism. Treatment of brown tumors must be initially directed towards correcting the hyperparathyroidism. Tumor regression may occur with resolution of the hyperparathyroidism. Persistent or large destructive tumors are treated with resection or curettage.- - - - - - - - - - ranking = 3.7469964616533keywords = mandible (Clic here for more details about this article) |
20/22. The management of lesions of the jaws with liquid nitrogen cryotherapy.The mandible and maxilla suffer from a number of lesions that, though benign, have a high recurrence rate (10 percent to 80 percent) after simple enucleation. These include the ameloblastoma, keratocyst, odontogenic myxoma, central giant cell granuloma and ossifying fibroma. The appropriate treatment of these lesions is controversial, eliciting accusations of both undertreatment and overtreatment. Liquid nitrogen cryotherapy may be a valuable treatment modality to prevent recurrences of these lesions without causing cosmetic deformity.- - - - - - - - - - ranking = 1.18975265376keywords = mandible, jaw (Clic here for more details about this article) |
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