1/13. Pleomorphic adenoma (benign "mixed" tumor) of the human female breast. Case report.A case of solitary pleomorphic adenoma, ("mixed" tumor of salivary gland type) of the left breast associated with the right breast fibroadenoma in 43-year-old woman is reported. The paper describes clinical, cytological, immunohistological and pathological findings in this case and indicates the importance of separating this benign entity from malignances with stromal metaplasia.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
2/13. Adenomyxoma of eccrine sweat gland--case report.Although eccrine adenoma is usually situated on the distal portions of the extremities, we present a case localized in the vicinity of a mammary gland near axilla. The clinical diagnosis was of a mammary fibroadenoma with associated apocrine type of adenomere, supported by a myxomatous stromal tissue. The diagnosis was of an eccrine adenomyxoma. We continue with a review of the problems of microscopical differential diagnosis.- - - - - - - - - - ranking = 5keywords = gland (Clic here for more details about this article) |
3/13. Clear cell syringofibroadenoma (of Mascaro) of the nail.Eccrine syringofibroadenoma (ESFA) is a rare disorder. We report the first case of ESFA of the nail apparatus, which presented as a yellow longitudinal onycholytic band of the left fourth finger over an intermittently painful subungual filamentous tumour. Histological examination showed features of ESFA with a digitate pattern of papillomatosis due to the specialized physiological longitudinal arrangement of the ridges in the nail bed. In addition, we describe a new feature of colloidal iron-positive clear cells. In our case, the presence of two types of cells with a central ductal differentiation and a significant amount of mucopolysaccharides in clear cells could suggest differentiation towards both the ductal and the secretory portion of the eccrine gland.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
4/13. fibroadenoma of the eyelid.Extramammary fibroadenomas have been previously reported to mainly occur in the anogenital region, arising from mammary-like glands. The present report describes a 45-year-old woman who presented with a fibroadenoma of her eyelid that was associated with a cystadenoma. To our knowledge, this is the first case report of a fibroadenoma of the eyelid. The differential diagnosis and histogenesis of this lesion are discussed, and the literature pertaining to cutaneous fibroadenomas arising outside the breast is reviewed.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
5/13. fibroadenoma of the vulva. A report of two cases.BACKGROUND: Vulvar fibroadenoma is a rare entity. It has been proposed that the tissue of origin is either ectopic breast tissue or vulvar mammarylike glands. Sporadic examples of benign and malignant vulvar tumors arising from such glands have been previously reported. CASES: We recently encountered two cases of vulvar fibroadenoma, one in a 29-year-old woman and one in a 42-year-old woman, with both neoplasms presenting clinically as vulvar cysts. CONCLUSION: fibroadenoma of the vulva is an uncommon lesion histologically similar to fibroadenoma of the breast. Clinicians need to be aware that the lesion can occur in this location.- - - - - - - - - - ranking = 2keywords = gland (Clic here for more details about this article) |
6/13. Adenoid cystic carcinoma arising in a fibroadenoma.Adenoid cystic carcinoma (ACC) of the breast is a rare neoplasm, accounting for only 0.1 % of all breast carcinomas. An intriguing factor of ACC in the breast is its good prognosis compared to ACC in other locations, mainly in the minor salivary glands. The incidence of axillary lymph node involvement is also very low compared to that of other breast tumors, and distant metastases are uncommon. We report the case of a 65-year-old woman with a 2-year history of a well-circumscribed breast nodule sonographically thought to be a lymph node which was later excised because of rapid growth. Histologic examination showed an adenoid cystic carcinoma with squamous differentiation originating in a fibroadenoma. A review of the literature reveals no previous report of such a case.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
7/13. Pseudoangiomatous stromal hyperplasia in lesions involving anogenital mammary-like glands.Pseudoangiomatous stromal hyperplasia (PASH), first reported in 1986, is nowadays a well-recognized change in the breast. We present three cases of lesions involving anogenital mammary-like glands demonstrating this feature. All patients were females (ages, 42, 43, and 53 years). Each presented with a solitary, 1.5- to 2-cm asymptomatic nodule. Locations included the perianal area, perineum, and labium majus. Histopathologically, one lesion was classified as low-grade phyllodes tumor, another as fibroadenoma, and in the remaining case PASH was found in the background of mild hyperplasia of anogenital mammary-like glands and substantial lipomatous metaplasia. In all lesions, PASH had an identical appearance to that in the breast, that is open, slit-like, often anastomosing channels devoid of erythrocytes and lined by discontinuous, often attenuated, inconspicuous cells without atypia or mitotic activity set in a hyalinized collagenous stroma. Quantitatively, PASH ranged in the above cases, forming a relatively small focus in the fibroadenoma and being quite extensive in the remaining two cases. In the phyllodes tumor, PASH areas exhibited focal hypercellularity and presence of myoid cells. In none of the cases were there cells with intranuclear inclusions or multinucleated cells. The lesions were surgically excised. Two patients with follow-up were disease-free at one and three years after the operation. As to our knowledge, PASH has not been previously described in the anogenital area, this feature seems to have been either overlooked or is genuinely rare in this location. It may occur in a preexisting lesion of anogenital mammary-like glands or may apparently by itself produce a clinically detectable lesion. The clinicopathologic features of PASH in the anogenital area seem to be identical to those in the breast.- - - - - - - - - - ranking = 7keywords = gland (Clic here for more details about this article) |
8/13. breast hamartoma: a case report.breast hamartoma is a benign and rare tumour consisting of glandular fat and fibrous tissue. A 36-year old woman was admitted to our clinic, complaining of a mass in her right breast since two months. Ultrasonographic and mammographic examinations revealed a 10 cm mass diagnosed as fibroadenolipoma. Total excision of the mass was performed without any complication. Histopathological examination revealed fibroadenomatous hamartoma.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
9/13. Mammary radioiodine accumulation due to functional sodium iodide symporter expression in a benign fibroadenoma.The sodium iodide symporter (NIS) has been characterized to mediate the active transport of iodide not only in the thyroid gland but also in various non-thyroidal tissues, including lactating mammary gland and the majority of breast cancers, thereby offering the possibility of diagnostic and therapeutic radioiodine application in breast cancer. In this report, we present a 57-year-old patient with multifocal papillary thyroid carcinoma, who showed focal radioiodine accumulation in a lesion in the right breast on a posttherapy (131)I scan following radioiodine therapy. CT and MR-mammography showed a focal solid lesion in the right breast suggestive of a fibroadenoma, which was confirmed by histological examination. Immunostaining of paraffin-embedded tumor tissue sections using a human NIS antibody demonstrated NIS-specific immunoreactivity confined to epithelial cells of mammary ducts. In conclusion, in a thyroid cancer patient we identified a benign fibroadenoma of the breast expressing high levels of functionally active NIS protein as underlying cause of focal mammary radioiodine accumulation on a posttherapy (131)I scan. These data show for the first time that functional NIS expression is not restricted to lactating mammary gland and malignant breast tissue, but can also be detected in benign breast lesions, such as fibroadenomata of the breast.- - - - - - - - - - ranking = 3keywords = gland (Clic here for more details about this article) |
10/13. New uses of mammary ultrasonography.This article reports the experience acquired through the use of ultrasonography applied to the study of the mammary gland affected by augmentation or reduction mammaplasty. Thirty-eight patients who had undergone either augmentation or reduction mammaplasty were submitted to ultrasonographic examination. Such a technique, besides being easy to perform, noninvasive, specific, and well accepted by the patients, showed to be remarkably interesting. It offered a wide display of the mammary parenchyma, showing its possible alterations, and supplying useful information on any possible postoperative implant ruptures, cicatricial reactions, seromas, and any other possible alterations that occurred.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
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