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1/79. skin necrosis induced by extravasation of glycerol-containing peripheral parenteral nutrition formulation.

    Administration of parenteral nutrition (PN) via a peripheral vein has gained support over the last decade due to serious complications associated with central venous catheterization. Extravasation and tissue necrosis have been reported with both peripheral and central dextrose-containing PN formulations. The following case report represents the first documented case of skin necrosis due to extravasation of a glycerol-containing PN formulation. Our patient's condition resolved with local therapy such as elevation of the affected extremity and cold compresses. Routine evaluation of proper catheter placement is recommended to prevent this serious morbid event, while various treatment recommendations are outlined for severe injuries that do not respond to general measures such as cold compresses.
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2/79. Magnetic resonance cystography with gadopenetate dimeglumine of a cystic craniopharyngioma in a child - a technical note.

    Large cystic craniopharyngiomas can be treated with chemotherapy injected directly into the cyst. Chemotherapy is toxic if it leaks from the cyst into the subarachnoid space. We present a child with a cystic craniopharyngioma following surgical placement of a catheter into the cystic component. Computed tomography following iodinated contrast injection into the cyst was inconclusive in determining the cyst wall integrity. Magnetic resonance following dilute gadopentetate dimeglumine injection into the cyst clearly defined a leak into the subarachnoid space. Coronal imaging was especially helpful. This technique is simple to perform and useful for clinical management.
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3/79. Extravasation of infusate via implanted ports: two case studies.

    Over the past two decades, implanted ports have become widely used infusion therapy devices. Although these devices have revolutionized the care of patients with cancer and are used routinely to administer various treatments, complications still can occur. nurses must be vigilant in identifying potential and actual port-related problems and aware that radiological studies may not immediately reveal a problem. Two unique case studies are described in which extravasation complications occurred despite negative initial catheter dye studies. A clinical algorithm is presented that outlines the management of a suspected port extravasation.
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4/79. diagnosis and management of spinal epidural space extravasation complicating percutaneous central venous line placement in a premature infant: case report and review of literature.

    Percutaneous central venous lines are commonly used to establish long-term venous access in the care of premature infants. Misplacement of these catheters can occur and may lead to significant morbidity and mortality. Here we report a very-low-birth-weight premature infant whose percutaneous central venous line was inadvertently placed into the spinal epidural space. The anatomical basis of this complication as well as a comprehensive review of literature are provided.
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5/79. Orbital compression syndrome after orbital extravasation of X-ray contrast material.

    PURPOSE: To report the orbital compression syndrome after orbital extravasation of x-ray contrast material during catheterization of the left middle meningeal artery. methods: Case report. RESULTS: A 61-year-old woman had profound loss of vision, pain, and proptosis of her left eye immediately after catheterization of the left middle meningeal artery. Computed tomography (CT) revealed that contrast material had extravasated into the orbit. Her symptoms improved with lateral canthotomy and cantholysis and resolved totally within 24 hours without the need for an orbital surgical procedure to remove the contrast material. CONCLUSION: This report describes an unusual cause of the orbital compression syndrome.
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6/79. Case report: total parenteral nutrition extravasation associated with spinal cord compression and necrosis.

    A preterm infant, whose course was complicated by sepsis, necrotizing enterocolitis with jejunal perforation, intraventricular hemorrhage and cerebellar hemorrhage, suffered permanent and total paralysis below the neck from extravasation of parenteral nutrition fluids through a femoral venous catheter. MRI imaging revealed extravasation of fluid into the paraspinus musculature with extension into the spinal canal. This fluid was identified as hyperalimentation and intralipid. Postmortem examination found evidence of necrosis of the spinal cord as well as perforation of the right iliac vein.
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7/79. Central venous catheterization and fatal cardiac tamponade.

    cardiac tamponade is a poorly recognized complication of central venous catheterization associated with a high mortality. We present a case of fatal cardiac tamponade after intra- pericardial infusion of total parenteral nutrition in a patient who had two central venous catheters. We suggest that catheter tip position should always be confirmed before use of a catheter. Tamponade should be suspected in a patient who deteriorates when a central venous catheter is used and resuscitation via the catheter should be avoided.
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8/79. Ipsilateral thoraco-lumbar anaesthesia and paravertebral spread after low thoracic paravertebral injection.

    We report ipsilateral thoraco-lumbar anaesthesia and paravertebral spread of contrast after injection through a thoracic paravertebral catheter that was placed at the right T8-9 spinal level for pain management in a patient with multiple fractured ribs. We review the literature and describe the subendothoracic fascial communication between the thoracic paravertebral space and the retroperitoneal lumbar paravertebral region, which we propose, is the anatomical basis for ipsilateral thoraco-lumbar anaesthesia and paravertebral spread of contrast in our patient.
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9/79. Total spinal anaesthesia in association with insertion of a paravertebral catheter.

    An association between intercostal nerve block and the development of a total spinal is rare. Usually, subarachnoid injection is considered to have followed intraneural placement or inadvertent entrance into a dural cuff extending beyond an intervertebral foramen. We report a patient that followed injection of local anaesthetic into a paravertebral catheter sited at surgery in the thoracic paravertebral space of a patient undergoing thoracotomy. This was a life-threatening event that occurred on two occasions before the definitive diagnosis was made. It is considered likely that the paravertebral catheter entered an intervertebral foramen and the tip perforated the dura.
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10/79. A rare complication of neonatal central venous access.

    Total parenteral nutrition is often necessary for the survival of neonates, but obtaining central venous access can be very difficult. A case is reported in which malpositioning of a 27 gauge central venous catheter resulted in the misdiagnosis of necrotising enterocolitis and hypoglycaemia.
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