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1/5. corynebacterium JK: surgical infections in non-immunosuppressed patients.

    infection caused by corynebacterium JK (CJK) has been recently described in immunocompromised patients. To evaluate the frequency of CJK infection among surgical and trauma intensive care patients, all patients with CJK isolations at clinical sites were reviewed. The criteria used were the presence of bacterial infection symptoms, isolation from significant sites and the efficiency of a vancomycin treatment. Eight patients were studied; 3 of them were considered infected, while 5 were judged only colonized. It is concluded that CJK infections can be a clinical problem in surgical trauma patients.
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keywords = bacterial infection
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2/5. Trichomycosis pubis.

    Trichomycosis is a bacterial infection of hair that involves the axilla and, uncommonly, the pubis. The causative agent of trichomycosis pubis is probably the same as that in trichomycosis axillaris, as determined by culture and electron microscopy. We believe that increased awareness of trichomycosis pubis will show it to be common in certain environments.
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keywords = bacterial infection
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3/5. corynebacterium equi: a review of 12 cases of human infection.

    corynebacterium equi, an aerobic, variably acid-fast, gram-positive "diphtheroid," is an unusual cause of pulmonary infection in immunosuppressed patients. Initially, infection with C. equi may be mistaken for a mycobacterial infection. Two cases in a two-year period were observed and compared with the 10 cases previously reported in the literature. All but one patient had pulmonary involvement, and the presentation of all other patients was typically insidious, with fatigue, fever, and nonproductive cough. Chest roentgenograms showed cavitary lesions in seven of 11 patients. Four of 12 patients had associated bacteremias, and three of 12 had subcutaneous abscesses or lymphadenitis. One of our patients developed multiple brain abscesses. overall mortality was 25%. The organism is susceptible to vancomycin, erythromycin, aminoglycosides, and chloramphenicol. Optimal duration of antibiotic therapy and the proper role of surgery in treatment is uncertain, but relapses have been common and many weeks of antibiotic therapy have generally been required for cure.
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keywords = bacterial infection
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4/5. corynebacterium group JK bacterial infection in a patient with an epicardial pacemaker.

    Septicemia caused by Corynebacteria group JK bacterium has previously been reported to occur in patients who have predisposing illness, such as neoplasms, ventriculoatrial shunt, or prosthetic valve. This study documents the case of an epicardial abscess caused by a corynebacterium group JK organism in a 69-year-old woman who had an epicardial pacemaker.
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keywords = bacterial infection
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5/5. Predisposition to corynebacterium jeikeium infection in acute lymphoblastic leukemia: a report of two cases in Trinidad.

    Two hospitalized patients (a 4 and 6 year old male and female, respectively) with acute lymphoblastic leukaemia (ALL), had each at different periods sustained burns with necrosis from extravasation of chemotherapeutic products. Pure cultures from their wound exudates and blood repeatedly revealed corynebacterium jeikeium, an organism recognized and identified in the last decade as an opportunistic cause of life-threatening nosocomial infections particularly in patients on long-term multiple antimicrobial therapy, and in those who are neutropenic or have cardiac valve replacement. The organism has been found to be highly resistant to many antibiotics but sensitive to a few, including vancomycin. Both patients were successfully treated with vancomycin and are reviewed here to emphasize the importance of this group of microorganisms resistant to multiple antibiotic therapy as possible frequent cause of subacute bacterial infection in immunodepressed conditions such as ALL, especially when external wounds are inflicted by extravasation of antileukaemic agents (notably, vinca alkaloids). A review of the literature indicates that these are the first reported cases of infection caused by these organisms in Trinidad, and it is of clinical and therapeutic interest to note that they are sensitive to norfloxacin, polymyxin, tetracycline, and particularly vancomycin in this study.
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ranking = 1
keywords = bacterial infection
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