1/46. Thyroid papillary carcinoma arising in ectopic thyroid tissue within a branchial cleft cyst.A case of papillary carcinoma arising in ectopic thyroid tissue within a branchial cleft cyst is described. A 46-year-old woman presented with a 2.0 x 2.0 cm mass in her left lateral neck. The excised mass showed a cystic lesion with a thyroid papillary carcinoma. Following a lateral cervical cystectomy, subsequent thyroid gland and lymph nodes dissections were performed. Pathological examination showed an adenomatous goiter and no primary carcinoma in the thyroid gland, as well as metastatic papillary carcinoma in the lymph nodes. Two cases of thyroid papillary carcinoma arising in ectopic thyroid tissue within a branchial cyst have been reported previously, but no lymph node metastases were recognized. The first case of papillary carcinoma arising in ectopic thyroid tissue within a branchial cleft cyst, and accompanied by lymph node metastasis is presented.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
2/46. Fine-needle aspiration cytology of lymphangioma of the parotid gland in an adult.lymphangioma or cystic hygroma is an uncommon benign congenital tumor of lymphatics that is seen in children and, rarely, adults. lymphangioma primarily involving the parotid gland is an extremely uncommon occurrence in adults. We report on the cytologic findings of a parotid lymphangioma in a 34-yr-old man which showed 13 cc of yellow fluid with red blood cells, lymphocytes, and rare fragments of benign-appearing salivary gland epithelium. The differential diagnosis of cystic parotid gland lesions in adults may include Warthin's tumor, lymphoma, benign lymphoepithelial lesions, branchial cleft cysts, chronic sialadenitis, cystic low-grade mucoepidermoid carcinoma, and cystic pleomorphic adenoma. In this case, the fine-needle aspiration findings along with the magnetic resonance imaging (MRI) findings of a multiloculated cystic mass in the parotid gland allowed the diagnosis of lymphangioma.- - - - - - - - - - ranking = 4keywords = gland (Clic here for more details about this article) |
3/46. An intra-thyroidal branchial cyst: a case report.Branchial cleft cysts were previously thought not to occur in the thyroid but have recently been described in two patients with Hashimoto's disease. This case report describes a patient with a branchial cleft cyst in an otherwise normal thyroid gland and could provide further evidence that thyroidal follicular cells are derived from the branchial clefts as well as from the primitive gut.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
4/46. cytodiagnosis of lesions presenting as salivary gland swellings: a report of seven cases.The cytologic and histologic findings of seven cases presenting clinically as salivary gland swellings are described. These included two cases of pilomatrixoma of skin in the parotid region, two cases of neurilemmoma in the submandibular area, a case of Kimura's disease in the peri-mandibular gland lymphoid tissue, a case of Castleman's disease in intraparotid lymph node, and a case of branchial cleft cyst in the parotid region. It is important to recognize lesions that masquerade as salivary gland tumors so that misdiagnosis and overdiagnosis on smears can be avoided and the patients can be treated appropriately.- - - - - - - - - - ranking = 3.5keywords = gland (Clic here for more details about this article) |
5/46. incidence of occult thyroid carcinoma metastases in lateral cervical cysts.PURPOSE: To establish the incidence of thyroid carcinoma metastasis in adult patients presenting with apparently benign cervical cysts. The authors report their experience with four cases of papillary thyroid carcinoma who present with a lateral cervical cystic mass and no palpable disease in the thyroid gland. MATERIALS AND methods: A retrospective review of patients undergoing surgery for solitary cervical cysts in our clinic from 1994 to 2002 was performed. patients with a clinically obvious primary malignancy, age less than 16 years were excluded from the study. RESULTS: Thirty-seven patients were identified. A diagnosis of benign cervical cyst was shown by histological examination of the resected specimen in 32 patients (86.4%), with a mean age of 34 years (range, 16-59 years). A diagnosis of squamous cell carcinoma metastasis arising from an occult tonsillary primary was confirmed histologically in one patient (2.7%). Papillary thyroid carcinoma metastasis was confirmed by histological examination of the resected specimen in 4 patients (10.8 %), with a mean age of 29 years (range, 18-37 years). Diagnostic studies performed included ultrasound, computed tomography scan, fine-needle aspiration (FNA), and excisional biopsy. FNA was found to be helpful in only one of the 3 cases with papillary thyroid carcinoma metastasis. Final histopathological examination exhibited primary focus in the thyroid gland in all 4 patients, with a mean size of 0.5 cm (range, 0.3-0.8 cm). CONCLUSION: Our data indicate that nearly 1 out of every 10 lateral cervical cysts in young adult patients represents lymphatic metastases from occult thyroid carcinoma. An excisional biopsy for definitive diagnosis should be undertaken without prolonged delay, even if FNA does not reveal malignancy.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
6/46. Intrathyroidal branchial cleft-like cyst with heterotopic salivary gland-type tissue.A rare case is described of intrathyroidal branchial cleft-like cyst associated with unusual heterotopic tissues including the salivary gland type tissue, fat, and cartilage. This coexistence in the thyroid gland has not been described previously, to our knowledge. The patient was a 7-year-old girl with a growing mass in the left lateral neck. The ultrasonography revealed a cystic lesion in the left thyroid. Histologically, the cyst was lined by squamous or respiratory-type epithelium resting on the fibrous tissue containing lymphoid tissues with follicle formation and solid cell nests (SCNs). This cyst was intimately associated with heterotopic tissues including lobules of well-differentiated seromucinous salivary glands, mature fat tissue, and islands of the cartilage. This association of branchial cleft-like cyst with SCNs and unusual heterotopic tissues in the normal thyroid suggests a possible origin from the SCN as ultimobranchial vestigial structures.- - - - - - - - - - ranking = 3.5keywords = gland (Clic here for more details about this article) |
7/46. Basal cell adenoma and lymphoepithelial cyst as recurrent tumors of pleomorphic adenoma of the parotid gland.Basal cell adenoma of the parotid gland is a rare benign tumor. Lymphoepithelial cyst of the parotid gland is also a rare benign tumor-like lesion. We report an elderly woman, who previously underwent a removal of pleomorphic adenoma, with multiple masses in the left parotid gland. Physical, MR and intra-operative examination suggested the masses as multiple recurrences of the previous pleomorphic adenoma. A total parotidectomy with facial nerve preservation was performed. The histological examination revealed that the masses were two basal cell adenomas and one lymphoepithelial cyst. These rare tumors should be considered in the differential diagnosis of recurrent masses after a removal of pleomorphic adenoma of the parotid gland.- - - - - - - - - - ranking = 4keywords = gland (Clic here for more details about this article) |
8/46. Heterotopic salivary gland tissue: a case report demonstrating evolution and association with the branchial apparatus.Heterotopic salivary gland tissue (HSGT) in the lower neck is an unusual developmental anomaly with characteristic clinical and microscopic findings. The exact embryogenesis remains unclear. This rare entity must be considered in the differential diagnosis of neck mass with fistula. We present a typical HSGT totally removed using the stepladder excision technique and showing an internal fistula. Interpretation of this case from the anatomical and pathological points of view, we support the argument that the embryogenesis of HSGT is more probably related to ectodermal heteroplasia of the precervical sinus of His and further conclude that an association with branchial cleft sinus may exist and cannot be seen as an exclusion criteria for diagnosis of HSGT. Due to possible but infrequent neoplastic transformation, it is important to check HSGT in every encountered cervical anomaly related to any branchial apparatus derived lesion.- - - - - - - - - - ranking = 2.5keywords = gland (Clic here for more details about this article) |
9/46. Branchial-like cysts of the thyroid associated with solid cell nests.Presented herein is the case of a 65-year-old man with a 20 year history of thyroid hypofunction. On sonography a cystic lesion 4 x 4 x 5 cm in largest diameter was found, replacing most of the right lobe of the thyroid gland. Microscopically, the lesion was composed of labyrinth-like cystic structures (LCS) lined by a few layers of benign-appearing squamous cells and filled by mucinous material. Adjacent to the cyst walls were discontinuous patches of a lymphoid tissue, composed of haloed centrocyte-like cells or germinal centers mostly depleted of germinal cells. Additionally, there were numerous squamous cell nests equivalent to solid cell nests (SCN), all of which were surrounded by a similar-looking lymphoid tissue. Rare SCN were thus cystically changed and contained a small amount of mucus. The SCN communicated with the LCS: the former represented the most distal outpouchings of the latter. The epithelial structures were surrounded by a loose collagenous adipocytic stroma with plump fibroblasts, which resembled the stroma often seen in lateral neck cysts associated with structures such as cartilage, accessory salivary gland tissues, cysts and accessory thyroid and thymus. Immunohistochemically, all lesional elements were negative for calcitonin and thyroglobulin. The results of the paper suggest that branchial cleft-like cyst have an origin in the ultimobranchial body.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
10/46. Branchial cleftlike cysts of the thyroid.Branchial cleftlike cysts of the thyroid gland are rare lesions. Although initially described in patients with chronic lymphocytic thyroiditis, these cysts have been reported in a variety of histologic settings. We present 2 case studies, 1 in a 30-year-old woman and 1 in a 50-year-old man. The mode of presentation and management of these cases, along with a literature review, is discussed in brief.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
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