Cases reported "Bacterial Infections"

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1/13. Anaerobic thyroid abscess from a thyroid cyst after fine-needle aspiration.

    BACKGROUND: Anaerobic abscess formation within a thyroid cyst is rare but still possible, although aerobic thyroid abscess formation in the thyroid gland after fine-needle aspiration (FNA) has been observed in immunocompromised patients. methods: This study describes the clinical manifestations, thyroid echography, cytologic finding, culture outcome, and treatment course of an anaerobic abscess formation within a thyroid cyst after FNA in a healthy subject. RESULTS: A 53-year-old male subject had rapid enlargement of a left thyroid cyst develop after second FNA. Frank pus was obtained through third FNA. The culture outcome was propionibacterium acnes, which was rich in saliva and one of the pathogens causing periodontitis and gingivitis. After adequate antimicrobial therapy, the abscess gradually diminished. CONCLUSIONS: This article reported, for the first time, on the formation of an anaerobic thyroid abscess after FNA in a healthy subject. We recommended careful aseptic procedure and adequate isolation processes, such as wearing a mask to avoid an unfavorable outcome as a result of a bacterial infection.
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2/13. Lacrimal gland enlargement in sickle cell disease.

    Sickle cell disease (SCD) may have ocular complications. We present the a case of a patient with SCD, with an acute painful episode involving the limbs and periorbital region, who also twice developed an unusual complication of recurrent bilateral lacrimal gland enlargement, not previously reported in the medical literature.
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3/13. Acute parapharyngeal space infections. A report of 12 cases.

    Parapharyngeal space infections are a serious condition with a significant morbidity and mortality. Twelve cases seen between 1987 and 1990 are described. From the clinical findings it was clear that the tonsils appeared to be the most common source of infection and not other aetiological factors, such as dental and salivary gland pathology. Computed tomography was excellent in delineating the mass, but if this is not available ultrasonography appears to be of benefit. Intravenous antibiotics and the appropriate surgical intervention, when indicated, is the treatment of choice. An excellent clinical response was experienced; however, in 25% of patients recovery was complicated by aspiration pneumonia.
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4/13. Clinical regression of infected pancreatic necrosis. Case report.

    Infected pancreatic necrosis was diagnosed clinically and radiologically in a patient admitted for acute pancreatitis. As free gas in the pancreatic area was recognized, antibiotic therapy (ceftriaxone) was empirically introduced, while surgical drainage was being planned. After the second week, the patient rapidly started to improve, to the point that he could be discharged home without operation. Control CT-scans and general laboratory tests, at this phase and later on, confirmed a still enlarged gland but free of infection or ongoing inflammation. cholelithiasis, which had been identified in an early ultrasound scan, was electively treated by cholecystectomy 2 mo after the onset of pancreatitis, in the absence of sepsis, and with uneventful recovery. This case illustrates the rare possibility of spontaneous regression of infected necrotic pancreatitis, without any type of operation or nonoperative drainage.
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5/13. Travellers' diarrhoea among children returning to the United Kingdom from visits abroad.

    Between January 1984 and March 1986, 10 children aged between 7 and 56 months were admitted to Queen Elizabeth Hospital for Children in london with chronic travellers' diarrhoea, after visiting the Indian subcontinent, france or morocco. All the children were born in the United Kingdom and had been in good health before their journey abroad. On return to england most of these children were malnourished and two of them (twins) had a post-infective, tropical malabsorption-like syndrome. There was a high incidence of positive stool cultures and, on small intestinal biopsy, histological abnormalities were present in six. Children from the United Kingdom travelling abroad are at risk of developing severe travellers' diarrhoea, with serious consequences to their health and nutrition. There is a need for intensive parental education before travelling and this could be achieved through community health workers.
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6/13. CDC group HB-5 as a cause of genitourinary infections in adults.

    Isolates from five patients with genitourinary infections diagnosed over a 7-week period were identified as CDC group HB-5. The organisms caused clinical presentations of pelvic inflammatory disease in three women and urethritis in the only male in the series. The remaining patient received surgical treatment for a Bartholin gland abscess. Since the clinical and temporal presentations were remarkable and the questions of sexual mode of transmission and strain relatedness were of concern, the five strains were examined further by multilocus enzyme electrophoresis and ribosomal dna typing. overall, the five clinical isolates were more closely related to each other than to the control strains. This is the first report describing genitourinary infections caused by group HB-5. While the pathophysiology of group HB-5 infections remains to be fully elucidated, the possibility that this organism may be sexually transmitted deserves further study.
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7/13. ACTH deficiency, hyperprolactinemia and benign intracranial hypertension. A case report.

    A 26-year-old female with ACTH deficiency, hyperprolactinemia and benign intracranial hypertension is reported. Her symptoms of adrenocortical insufficiency and persistent amenorrhea appeared after her last child birth one year previously. During an infectious disease she became critically ill with hypotension and was treated with iv penicillin. A bacterial infection was, however, not diagnosed. After 4 days she developed symptoms and signs of intracranial hypertension. She improved gradually within 10 days without specific therapy against the intracranial pressure. Endocrine investigation disclosed a secondary adrenocortical failure. The lesion appeared to be located in the pituitary gland since plasma ACTH and cortisol did not respond to CRH. A moderately elevated serum PRL was found, whereas the pituitary reserves of TSH, GH, LH and FSH were normal, as was a computed tomographic scan of the pituitary gland. The patient was given cortisone substitution therapy and recovered immediately. Within the following year she regained normal menstruations and became pregnant. A possible autoimmune etiology of her isolated ACTH deficiency precipitated in the puerperium is discussed.
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8/13. A clinicopathological study of 15 autopsy cases with allogeneic bone marrow transplantation in special reference to graft versus host disease (GVHD).

    A clinicopathological investigation was made on 15 autopsy cases with allogeneic bone marrow transplantation. Engraftment was recognized in 11 patients, 6 out of which survived more than 100 days postgrafting, and 5 terminated within 100 days. The other patients succumbed to sepsis before engraftment. In 8 evaluated cases with clinical acute graft versus host disease (GVHD), involvement of acute GVHD was histologically confirmed in the skin, liver, and/or intestine. Atypical ductal changes similar to those of interlobular bile ducts were noted in the pancreas and esophageal gland in a patient with severe acute GVHD. Although 6 long-term patients showed neither definite lichenoid papulae nor sicca syndrome diagnostic for clinical chronic GVHD, 4 patients exhibited prolonged hepatic dysfunction and/or abnormal serological tests suggestive of autoimmunity, and they had some degree of basal vacuolar degeneration with or without lymphocytic infiltrates in the dermis, and atypical degeneration of small bile ducts at the same level as seen in acute GVHD ranging 20 to 50 micron in diameter. Chronic sialoadenitis with atypical epithelial degeneration was evident in two of them. A major cause of death was interstitial pneumonia of viral or fungal etiology due to persistent immunodeficiency.
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9/13. Piriform sinus fistula as a route of infection in acute suppurative thyroiditis.

    A case of acute suppurative thyroiditis due to a left piriform sinus fistula was reported. A five-year old boy had a acutely painful tumor in the anterior part of the neck. It was a diffuse, firm, warm erythematous tumor, and laboratory, radiologic findings showed the acute inflammation of the left lobe of thyroid. a barium swallow revealed a very thin fistula originating from the apex of the left piriform sinus extending antero-inferiorly. This fistula was considered to be a route of infection in acute suppurative thyroiditis, allowing bacterial infection to begin in the perithyroidal space and spread to the thyroid gland. The complete fistulectomy was required for a permanent cure, but an administration of antibiotics was very effective in this case.
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10/13. Skene's gland calculi produced by a ureaplasma urealyticum infection.

    We report a case of calculi in a Skene's gland abscess produced by ureaplasma urealyticum. The enzyme urease, produced by the ureaplasma urealyticum, is thought to be the etiological factor in stone production, vaginitis and urethritis.
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