1/11. Bacteriological and serological findings in a further case of transfusion-mediated yersinia enterocolitica sepsis.A 13-year-old patient developed severe shock due to administration of a Yersinia enterocolitica-contaminated red blood cell concentrate. Y. enterocolitica (serotype O:9, biotype II) was cultivated from the residual blood in the blood bag and from a stool sample of the blood donor. In the donor's plasma immunoglobulin m (IgM), IgA, and IgG antibodies against Yersinia outer proteins (YopM, -H, -D, and -E) were found. Since the donor remembered a short-lasting, mild diarrhea 14 days prior to blood donation, a transient attack of Yersinia enteritis may be associated with a longer than expected period of asymptomatic bacteremia that causes contamination of donor blood. Serological screening for IgM antibodies against Yersinia outer proteins might offer a way to reduce the risk of transfusion-associated Y. enterocolitica sepsis.- - - - - - - - - - ranking = 1keywords = sample (Clic here for more details about this article) |
2/11. Fatal yersinia enterocolitica biotype 4 serovar O:3 sepsis after red blood cell transfusion.BACKGROUND: Although posttransfusion bacterial sepsis is rare, this complication is associated with a high mortality rate. CASE REPORT: A fatal case of septic shock was observed in a 71-year-old patient following transfusion of contaminated red blood cells (RBCs) for refractory anemia. yersinia enterocolitica was isolated from the patient's blood sample and the transfused RBCs. Both strains were of bioserotype 4/O:3 and had the same NotI pulsotype. High titers of antibodies against Y. enterocolitica were detected in the donor's plasma sample 1 month after blood donation. The donor reported abdominal discomfort 3.5 months before blood collection but had no clinical signs of intestinal infection at the time of donation. CONCLUSION: Y. enterocolitica has been identified with increased frequency as a causative agent of posttransfusion septic shock. This nationwide investigation of these cases led to an estimated incidence of one case per 6.5 million RBC units distributed in france. Although rare, this often fatal complication remains nonpreventable worldwide owing to the lack of practical means for screening RBCs before transfusion.- - - - - - - - - - ranking = 2keywords = sample (Clic here for more details about this article) |
3/11. yersinia enterocolitica biotype 2 serotype O9 septicaemia in a previously fit man, raw goats' milk having been the apparent vehicle of infection: a cautionary tale.A previously fit 66-year-old man presented with a 2 weeks' history of malaise, fever and vomiting which led to a septicaemic illness. yersinia enterocolitica biotype 2 serotype O9 was isolated from the patient's blood and from raw goats' milk remaining in a bottle after the patient had consumed some of the contents. He also produced antibodies to this serotype. Careful history taking, however, revealed that the bottle of milk had been purchased after the patient became ill. milk from the same bottle was consumed by his wife who neither became ill nor seroconverted. Furthermore, the organism was not isolated from further samples from the same supplier. The milk consumed by the patient was probably contaminated by him so that initial enthusiasm in attributing his infection to the consumption of raw goats' milk is not supported by the facts. This case illustrates some of the pitfalls of trying to determine the vehicle of infection in a single case.- - - - - - - - - - ranking = 1keywords = sample (Clic here for more details about this article) |
4/11. yersinia pseudotuberculosis infection contracted through water contaminated by a wild animal.We performed epidemiological studies on yersinia pseudotuberculosis in one valley where a 3-year-old boy had been infected with Y. pseudotuberculosis serotype 4b in December 1982. Y. pseudotuberculosis serotype 4b was isolated from a water sample derived from a mountain stream from which the boy had drunk and from 1 of 41 rats trapped in the upper part of this stream in December 1986. The restriction endonuclease patterns of the plasmids in these isolates showed the rat and patient isolates to be identical but distinct from the water isolate. These data suggest the potential for transmission of Y. pseudotuberculosis through water contaminated by nondomesticated animals carrying this species.- - - - - - - - - - ranking = 1keywords = sample (Clic here for more details about this article) |
5/11. Haemolytic uraemic syndrome associated with yersinia enterocolitica infection.Haemolytic uraemic syndrome (HUS) associated with yersinia enterocolitica gastroenteritis is reported in a 6-year-old girl. Y. enterocolitica of biotype 03 was isolated from the patient's initial stool sample and was subsequently identified as serotype 03 based on the rising agglutinin titres. This paper shows that yersiniosis should be suspected as a possible cause of HUS, and investigations should include the measurement of serum agglutinin titres against antigen preparations of the genus Yersinia.- - - - - - - - - - ranking = 1keywords = sample (Clic here for more details about this article) |
6/11. Bacterial shock due to transfusion with yersinia enterocolitica infected blood.A fatal case (a 55-yr-old man) of bacterial shock and sepsis following a transfusion with erythrocytes infected with yersinia enterocolitica serotype 03, is reported. The blood donor had slight diarrhea 6 days before the blood donation. A serum sample from the donor showed high titre of both IgG and IgM antibodies against Y. enterocolitica 03, indicating a recent infection. Y. enterocolitica 03 was isolated from blood cultures from the patient. The remaining portion of the transfused erythrocyte concentrate also yielded abundant growth of the same organism on direct plating of the material on blood agar indicating that profuse multiplication of the organism had occurred within the transfusion bag during storage at 4 degrees C.- - - - - - - - - - ranking = 1keywords = sample (Clic here for more details about this article) |
7/11. panniculitis-like lesions in yersiniosis.infection with yersinia enterocolitica usually procedures gastrointestinal symptoms. We here report a severe case of panniculitis-like lesions caused by yersinia enterocolitica where only mild gastrointestinal symptoms were noticed. Blood samples revealed high yersinia enterocolitica serotype 3 titres, increased ESR, leucocytosis, and in addition yersinia enterocolitica was cultured from the faeces. When panniculitis-like lesions are the only clinical manifestation yersiniosis should be considered as a possible cause.- - - - - - - - - - ranking = 1keywords = sample (Clic here for more details about this article) |
8/11. Yersinia frederiksenii infection and colonization in hospital staff.A diagnosis of gastrointestinal infection with Yersinia frederiksenii was made in a 24-year-old female hospital doctor, resident in hospital. An additional three of nine medical residents screened were found to be faecal carriers of Y. frederiksenii. The latter three residents denied any gastrointestinal symptoms. Screening of 25 resident nurses and 25 in-patients for carriage of Y. frederiksenii was negative. Initial investigation revealed that the medical residents frequently drank unpasteurized milk, which was supplied on the understanding that it would be used for cooking only. Counts of > 10(8) cfu l-1 were obtained from unpasteurized milk samples, including 24 species of Gram-negative bacilli. Yersinia spp. were not isolated. Residents also drank water from the cold taps in the bedrooms; this water was supplied by a holding tank on the hospital roof. Subsequent investigations revealed that three of the 21 holding tanks supplying stored water to the hospital were not covered. Y. enterocolitica was isolated from the uncovered water tank supplying the medical residence.- - - - - - - - - - ranking = 1keywords = sample (Clic here for more details about this article) |
9/11. yersinia enterocolitica transmission from a red cell unit 34 days old.In 1993 the North london blood transfusion Centre received its first report of yersinia enterocolitica transmission from a unit of red cells supplied to a local hospital. The recipient was a 23-year-old male who was neutropenic following a third cycle of chemotherapy for treatment of acute myeloblastic leukaemia (FAB type M6) and received a 34-day-old red cell unit. During transfusion the patient developed septicaemia and endotoxin-mediated shock. The transfusion was stopped immediately and broad spectrum antibiotics administered immediately on suspicion of bacteraemia from the transfused unit. This prompt action undoubtedly prevented a fatal outcome. Y. enterocolitica was isolated from the blood bag. Antibody was also detected in the bag and in a sample taken from the donor 39 days post-donation. Antibody to serotype 03 was identified, the commonest serotype reported in transfusion-transmitted Y. enterocolitica. The donor reported no gastrointestinal upset or illness prior to donation. This transfusion reaction might not have occurred had the red cells been transfused earlier in their storage period, but would not have been prevented by the exclusion of donors with a history of gastrointestinal illness as the donor was asymptomatic. Nor would it have been prevented by inspecting the blood for a change in colour, as no such change was observed. Y. enterocolitica is a significant problem in transfusion medicine and transmission is generally associated with a high mortality rate. hospitals should be urged to investigate bacteriologically all appropriate transfusion reactions so that the true extent of the problem in the United Kingdom can be assessed.- - - - - - - - - - ranking = 1keywords = sample (Clic here for more details about this article) |
10/11. Yersinia-related arthritis in the Pacific Northwest.Serologic evidence of yersinia enterocolitica infection was sought by agglutination testing in serum samples from several populations, including Haida Indians, red cross blood donors, and Caucasian patients with rheumatoid arthritis, ankylosing spondylitis, and Reiter's syndrome. No evidence was found to indicate that yersinial infection was etiologically related to Haida spondylitis or Reiter's syndrome. Four of 28 patients with acute arthritis were diagnosed from serologic evidence as having Yersinia-related arthritis.- - - - - - - - - - ranking = 1keywords = sample (Clic here for more details about this article) |
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