1/10. Gastric adenocarcinoma with tonsil and submaxillary gland metastases: case report.Local invasion, hematogenous and lymphatic metastases are the major modes of spreading gastric cancer. The most common sites of metastases in patients with gastric cancer are liver, peritoneum, omentum, lungs and mesentery. Of the two pathological types of gastric cancer, intestinal-type gastric cancer showed preferential metastasis to the liver, whereas the diffuse-type showed a preference for peritoneal involvement and lymph node metastasis. However, metastases of gastric cancer to the head and neck regions are not common. The hematogenous route appears to account for a great majority of metastases to the head and neck regions. Malignant neoplasm metastases to major salivary glands or tonsils are not common. Several patients with cancers from the infraclavicular area have been reported with parotid gland or tonsil metastases. However, metastasis of gastric adenocarcinoma to the tonsils or submandibular glands is rare. We present a patient with recurrent gastric adenocarcinoma with both tonsil and submandibular gland metastases which is even rarer.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
2/10. Transmucosal fine-needle aspiration diagnosis of intraoral and intrapharyngeal lesions.OBJECTIVES: The effectiveness of fine-needle aspiration biopsy (FNAB) for the diagnosis of neck, thyroid, and salivary gland masses is well documented. Very few reports explore the potential of an intraoral FNAB approach for the diagnosis of submucosal lesions. We describe our technique and present case examples of pertinent differential diagnostic entities. We recommend an expanded role for FNAB of the oral cavity and oropharynx. STUDY DESIGN: Retrospective review. methods: A uniform technique was employed for transmucosal FNAB of 76 patients with intraoral masses. In applicable cases, cytology results were compared with traditional biopsy methods and permanent histopathologic specimens for accuracy. RESULTS: Our experience demonstrates the high sensitivity (93%) and specificity (86%) of intraoral FNAB when compared with biopsy by conventional means. FNAB provides distinct advantages for the cytologic diagnosis of submucosal lesions, which may be difficult to reach and adequately sample through conventional biopsy. FNAB of the tonsil and tonsillar fossa provides a safe and effective means of diagnosing both lymphoma and squamous cell cancer. Transmucosal FNAB via the mouth led to rapid diagnosis of a number of benign and malignant lesions. Applying this uniform FNAB technique, we had no significant complications. CONCLUSION: We recommend transmucosal FNAB as an effective means for highly accurate diagnosis of submucosal lesions of the oral cavity and oropharynx. CLINICAL RELEVANCE: Traditional biopsy techniques in the oral cavity may require anesthesia and may have diagnostic difficulties, particularly for submucosal lesions. Transmucosal FNAB overcomes these shortcomings by providing a minimally invasive means to rapid diagnosis of intraoral lesions.- - - - - - - - - - ranking = 0.125keywords = gland (Clic here for more details about this article) |
3/10. dental caries after radiotherapy of the oral regions.Five cases of dental caries after radiation therapy of the oral regions for treatment of carcinomas are presented. The differences in clinical appearance and behavior between radiation caries and ordinary smooth-surface dental caries are described. The role of salivary gland irradiation and the resultant xerostomia in the development of these lesions is discussed. Some explanations are offered as to how these lesions develop in the light of current knowledge concerning plaque and the development of dental caries. Several measures that may be taken to reduce the incidence and severity of these lesions are suggested.- - - - - - - - - - ranking = 0.125keywords = gland (Clic here for more details about this article) |
4/10. Congenital stalked fibromatous polyp of the superior pole of the tonsil containing hairless sebaceous glands.A polyp of the size of a small bean was discovered incidentally on the superior pole of the right tonsil of a 29-year-old man. Morphologically it bore a considerable resemblance to the immature infantile variant of the sebaceous-gland nevus, the Naevus epitheliomatosus sebaceus Wolters, but its top was mature. The polyp is viewed as a congenital dysontogenic tumor which, owing to its fibromatous basis, lack of hair, and its immature and mature sebaceous glands, may be informally classified as a "missing link" between the haired pharyngeal polyp and the pure pharyngeal fibroma.- - - - - - - - - - ranking = 0.75keywords = gland (Clic here for more details about this article) |
5/10. Polymorphous low-grade adenocarcinoma of the tonsil: report of a case and review of the literature.Polymorphous low-grade adenocarcinoma (PLGA) is a relatively common malignancy of the oral cavity, representing 7% to 11% of all intraoral minor salivary gland tumors, and 19% to 26% of those that are malignant. However, it is a rare finding in the oropharynx, with only 6 cases reported in the medical literature. The clinical features of a case of PLGA of the tonsillar fossa in a 64-year-old gentleman are presented, only the second such case reported in the medical literature. A review and discussion of the literature pertaining to PLGA of the oral cavity and the oropharynx is provided. (Am J Otolaryngol 2002;23:297-299.- - - - - - - - - - ranking = 0.125keywords = gland (Clic here for more details about this article) |
6/10. Anaplastic small cell (oat cell) carcinoma of the tonsils: report of two cases.Two cases of anaplastic small cell (oat cell) carcinoma of the tonsils are presented. In the first, cervical metastases preceded the manifestation of the primary tumour by 2 years. In case 2 the tonsillar carcinoma was accompanied by a bronchial tumour of the same histological type and by cervical and axillary metastases. Positive Grimelius stain, positive immunohistochemical staining for chromogranin a and neurone-specific enolase and the presence, in case 1, of membrane-bound granules indicate that these tumours display many similarities with neuroendocrine carcinomas even if they originate from pluripotential ductal cells of tonsillar minor salivary glands and not from Kulchitsky-like cells.- - - - - - - - - - ranking = 0.125keywords = gland (Clic here for more details about this article) |
7/10. Hodgkin's lymphoma of the oropharyngeal region: report of four cases and diagnostic value of monoclonal antibodies in detecting antigens associated with reed-sternberg cells.In a review of more than 500 cases from the lymphoma Registry, Department of Anatomic pathology, University Hospital Purpan, Universite Paul Sabatier, Toulouse, france, four cases of primary lesions in the oropharyngeal region were found. There were two lesions in the palatine tonsil, one in the nasopharynx, and one in the parotid gland. The average age of the patients was 54.5 years (range, 37 to 70 years), and all patients were men. The histologic types were lymphocyte predominance (one case), nodular-sclerosis (one case), and mixed cellularity (two cases). The patients were respectively staged as IAa, IIAa, and IIIA. They were treated with radiation, chemotherapy, or both. All four patients are now free of tumor and have been followed from 18 months to more than 6 years after definitive diagnosis and appropriate therapy. immunohistochemistry significantly contributes to the differential diagnosis of atypical Hodgkin's disease from non-Hodgkin's lymphomas, especially in extranodal sites. Dako-EMA and Leu-M1 monoclonal antibodies are reactive, respectively, with L and H variants (Dako-EMA , Leu-M1-) in the lymphocyte predominance type (Type 1) and with reed-sternberg cells (Dako-EMA-, Leu-M1 ) in the nodular-sclerosis (Type 2), mixed cellularity (Type 3), and lymphocyte depletion (Type 4) types.- - - - - - - - - - ranking = 0.125keywords = gland (Clic here for more details about this article) |
8/10. Acinic cell carcinoma of intraoral minor salivary gland origin.A case of acinic cell carcinoma involving minor salivary gland tissue is reported. This is an exceptional occurrence. The response to radiotherapy is described and it is suggested that this form of treatment should be considered in these cases.- - - - - - - - - - ranking = 0.625keywords = gland (Clic here for more details about this article) |
9/10. Tumours metastasizing to the head and neck--a report of seven cases.Metastatic tumours involving the head and neck region are rare. Over the past 18 years, seven such cases were treated at our clinic. Of those, four were in one of the paranasal sinuses, three had arisen from a primary hepatocellular carcinoma and one from an osteogenic fibrosarcoma of the leg. In the remaining three cases, metastases to the larynx, the tonsil, and the parotid gland arose from a primary renal cell carcinoma, a thyroid carcinoma, and a breast carcinoma, respectively. In metastatic tumours, the primary site can often be identified by the histopathological features. Accordingly, when malignant head and neck tumours are suspected of being metastatic in character, it is important to search carefully for the primary site.- - - - - - - - - - ranking = 0.125keywords = gland (Clic here for more details about this article) |
10/10. A mucosa-associated lymphoid tissue (MALT) type lymphoma (marginal zone B-cell lymphoma) from the palatine tonsil.The clinicopathologic and immunologic features of a low-grade B-cell non-Hodgkin's lymphoma that arose in the palatine tonsil are presented here. The histologic findings were similar to the mucosa-associated lymphoid tissue (MALT) type lymphoma described in the gastrointestinal tract and glandular tissues. The histogenesis, differential diagnoses and classification of these tumors are briefly discussed in the light of recent findings and proposals by the International lymphoma Study Group (ILSG). A literature survey revealed that MALT-lymphomas are exceptionally rare in Waldeyer's ring. Pathologists should be aware of the possible occurrence, albeit rare, of this tumor when confronted with a low-grade B-cell lymphoma from Waldeyer's ring.- - - - - - - - - - ranking = 0.125keywords = gland (Clic here for more details about this article) |
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