111/196. Human bite marks. Differential diagnosis. Human bite marks are common findings in cases of fights among children, child abuse, sexual abuse, among institutionalized persons, and in a number of homicide cases. Human bites can mimic annular or arciform dermatoses. These are reviewed from both a clinical and histologic viewpoint. An example is presented of a 2 year-old girl with several annular lesions that were clinically mistaken for a dermatophyte infection. Antifungal medications were ineffective. After several days, a dermatologist identified the lesions as human bites. physicians and other health care workers must be able to differentiate the clinical appearance of bite marks from other dermatologic diseases at an early stage so as to initiate proper therapy and counseling and, if indicated, a search for the perpetrator. ( info) |
112/196. Treatment with itraconazole of widespread tinea corporis due to trichophyton rubrum in a bone marrow transplant recipient. An immunocompromised patient, 6 weeks after bone marrow transplantation, developed extensive skin infection due to trichophyton rubrum. Because she could not tolerate ketoconazole and was hypersensitive to griseofulvin, she received itraconazole with complete recovery within 30 days. This case demonstrates that itraconazole may be effective treatment for dermatophytosis, even in immunocompromised hosts, and that there is no cross-reactivity between ketoconazole and itraconazole. ( info) |
113/196. tinea of the glans penis. A 56-year-old Japanese man with tinea of the glans penis is described. He did not carry any other tinea lesions except that of the glans penis. Mycological examinations revealed that the causative organism was trichophyton mentagrophytes. ( info) |
114/196. Differential diagnosis of unusual skin diseases in infants. There are a number of relatively unique clinical skin diseases that may develop on the buttocks of infants. These include iatrogenic skin diseases caused by external medicine; skin tumors caused by methylrosaniline chloride (Pyoktanin); atrophy of the skin due to steroidal liniments; nevus and tumor diseases, such as nevoxanthoendothelioma and Letterer-Siwe disease. Finally, there is chronic granulomatous disease. These unusual cases are reviewed and their differential diagnoses discussed. ( info) |
115/196. An immunosuppressive serum factor in widespread cutaneous dermatophytosis. A patient had a widespread dermatophytosis and a serum factor that specifically suppressed his T-cell rosette formation and the phytohemagglutinin responsiveness of his lymphocytes. The patient was also unable to mount a delayed hypersensitivity reaction to a standard anergy panel, although he did exhibit an immediate type hypersensitivity reaction to the trichophytin skin test antigen. Although many immunosuppressed patients succumb to severe bacterial and fungal infections, it is our contention that in certain cases the infectious process itself may generate a serum factor that is capable of inducing immunosuppression, thereby rendering the patient susceptible to further spread of the infection. ( info) |
116/196. Disuse contractures in a patient with tinea manuum and irritant contact dermatitis. Disuse contractures are reported in a patient with tinea manuum and irritant contact dermatitis. The case is presented to alert the physician to the potential for this problem in any patient with a chronic fissured dermatosis of the hands. ( info) |
117/196. Deep dermatophytosis to trichophyton rubrum and T. verrucosum in an immunosuppressed patient. A patient treated with immunosuppressant drug therapy for a non-Hodgkin's lymphoma and who presented with a tinea corporis developed a sudden outbreak of numerous subcutaneous nodules. Deep-seated hyphae and spores were found in skin biopsy specimens. There was no evidence of keratin debris or histologic features of granulomata and giant cells. Cultures from tinea and nodules grew trichophyton rubrum and T. verrucosum. There are no more than 60 cases of deep dermatophytosis reported in the literature. ( info) |
118/196. tinea faciei caused by microsporum canis in a newborn. A case of tinea faciei caused by microsporum canis in a 14-day-old infant is reported. The incubation period was seen to be 1 week. This was a familial infection which also affected the infant's grandmother and their pet cat and dog. Topical treatment with clotrimazole controlled the infection in the baby. A review of 14 cases (including our own) of dermatophytosis in newborn infants reported in the Japanese literature showed that newborn infants might be infected by several of these agents. ( info) |
119/196. tinea of the face caused by trichophyton rubrum with histologic changes of granuloma faciale. We report a case of tinea of the face caused by trichophyton rubrum in which the histologic changes were consistent with granuloma faciale. We recommend that local infection with dermatophytes be considered in all cases of histologic granuloma faciale, especially when the clinical presentation is atypical for this dermatosis. ( info) |
120/196. tinea faciei in infants caused by trichophyton tonsurans. tinea faciei has been observed periodically in children, however, it is a relatively rare occurrence in infancy. We examined three infants with tinea faciei caused by trichophyton tonsurans. Two of the patients were potassium hydroxide (KOH) negative for fungal hyphae but culture positive, while the third was both KOH and culture positive. trichophyton tonsurans was isolated from the scalp of family members in two of the three infants. ( info) |