1/22. color Doppler findings of tumor seeding after US-guided liver tumor biopsy.We present two cases with tumor seeding along the needle tract occurring after a large-core needle liver tumor biopsy performed at other hospitals. color Doppler sonography showed the hypervascular nature of the lesion and increased diagnostic confidence.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
2/22. rhabdomyosarcoma in a child with massive pleural effusion: cytological diagnosis from pleural fluid.We report on a case of embryonal rhabdomyosarcoma in an 11-yr-old boy investigated for mild chest pain after trauma. Chest radiography showed a massive right pleural effusion. Cytological analysis of the pleural fluid demonstrated the presence of malignant small undifferentiated cells. The rhabdomyoblastic nature of the cells was confirmed by positive immunostains of HHf35 actin, desmin, and skeletal muscle myosin; histological examination of a core biopsy confirmed the diagnosis of rhabdomyosarcoma. Computed tomography and gallium scan revealed the presence of an extensive anterior and lower chest wall mass involving the mediastinum, as well as retroperitoneal lymphadenopathy. Massive pleural effusion is a frequent presentation in malignant disease, but is rare in rhabdomyosarcoma. The immunochemical stain studies performed on cytological smears in this case proved to be very useful for making the definitive and accurate diagnosis. Diagn. Cytopathol. 1999;21:125-128.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
3/22. Massive intrathoracic extrapleural haemangiopericytoma: deployment of radiotherapy to reduce vascularity.Haemangiopericytoma is a rare, highly vascular, slow-growing tumour which has both malignant and benign varieties. We report a case of a 63-year-old man in whom it was treated by initial radiotherapy followed by complete surgical excision. The preoperative radiotherapy markedly reduced the vascularity of the tumour. A brief review of the pathology and nature of tumour is provided.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
4/22. lipoblastoma: better termed infantile lipoma?lipoblastoma is a rare adipose tumor occurring exclusively in childhood. There have been no reports of metastases, making the designation "blastoma" confusing, since this term is usually reserved for malignant tumors. Two recent cases treated at our institution confirm its benign nature. In addition, a review of the literature supports the idea that the tumor may more accurately be described as an "infantile lipoma". Infantile lipoma better reflects many of the tumor's characteristics such as, its early occurrence, it's ability to mature into a simple lipoma, it's cellular composition of mainly mature adipocytes, and its benign course. Although lipoblastoma is an uncommonly encountered tumor, making an effort to change its name to infantile lipoma will result in a more a accurate term that will facilitate treatment.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
5/22. Askin tumor: a malignant small cell tumor.Malignant tumours of the chest wall are rare in the pediatric age group. Askin tumour, a primitive neuroectodermal tumour with aggressive nature, is extremely rare. Clinico-pathological features make it quite distinct from Ewing's sarcoma. Aggressive nature of the tumour results in short clinical presentation of the patient. Diagnosis of Askin tumour is mainly by histo-pathology. Imaging modalities play only a complimentary role. We present a case diagnosed to have this rare malignant tumour in the thoraco-pulmonary area in a child.- - - - - - - - - - ranking = 2keywords = nature (Clic here for more details about this article) |
6/22. Bilateral elastofibroma dorsi.Elastofibroma dorsi was diagnosed in a 48-year-old woman with bilateral subscapular tumor masses diagnosed asynchronously in an interval of 4 months in spite of presence of another lesion at first admittance. She underwent subsequent resections of the lesions. They were diagnosed as elastofibroma. Reevaluation of the initial computerized tomography of thorax indicated an omitted small lesion with a 2-cm diameter and 25.2-day doubling time. Although the real neoplastic nature of elastofibroma is unknown, bilateral presence of the masses with different sizes and relatively short doubling times of the lesions must be kept in mind.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
7/22. Extra-abdominal desmoid tumor presenting as an intrathoracic tumor: case report and literature review.A case of an extra-abdominal desmoid tumor presenting as an intrathoracic tumor (intrathoracic desmoid tumor) in a 46-year-old woman is reported. The tumor originated in the left chest wall and protruded into the left pleural cavity. Simple resection was carried out. The tumor, measuring 13 x 9 x 7 cm, was solid, gray-tan in color, and covered with parietal pleura. Histologically, the tumor was composed of a hypocellular arrangement of spindle-shaped cells with a fibromyxoid background. In some areas, keloid-like hyalinized collagen fibers proliferated, and a perivascular hypercellular area was seen. Immunohistochemical analysis showed that the cytoplasms of the tumor cells were strongly positive for vimentin, and some tumor cells were positive for alpha-smooth muscle actin, but all tumor cells were negative for CD34. These findings were consistent with the characteristics of an intrathoracic desmoid tumor. The differential diagnoses, in particular solitary fibrous tumor and tumors with a myofibroblastic nature, are discussed.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
8/22. cytodiagnosis of extrapleural tumors in multiple myeloma by fine needle aspiration. A report of three cases.Cytologic and immunocytochemical studies were done on fine needle aspirates of extrapleural tumors from three patients with multiple myeloma. In the first case the cytologic findings were consistent with myeloma, but the immunochemical studies were done improperly and were not interpretable. In the second case the cytologic findings were those of acute inflammation despite the strong clinical suspicion of the thoracic lesion's malignancy. In the third case both the cytologic and immunocytochemical findings were diagnostic of plasmacytoma. Our experience with these cases suggests that an assessment of the nature of the extrapleural tumor is indicated even in patients with known myeloma, that fine needle aspiration (FNA) is the diagnostic procedure of choice under the circumstances and that immunocytochemical studies can enhance the diagnostic accuracy of FNA for plasmacytoma. The best results for assessment of the cytologic FNA findings in extrapleural tumor in myeloma can be achieved by proper execution of both the FNA procedure and immunochemical studies and by interpretation of the cytologic findings within the context of the clinical findings.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
9/22. Progression of chromosome abnormalities after radiation therapy in a patient with Askin's tumor.A patient previously reported to have Ewing's sarcoma showed a t(11;22) (q23;q11) and spontaneous expression of fra(11)(q23) [1]. Subsequent review of pathologic specimen indicated, however, that it was an Askin's tumor. Reciprocal translocations of chromosomes 11 and 22 are the most common cytogenetic abnormalities in Ewing's sarcoma and the related Askin's tumor. After radiation therapy of a residual metastatic brain lesion, subsequent studies of the recurrent brain tumor indicated the presence of the original translocations as well as five new reciprocal translocations and two deleted segments (9p-, 10p-). The new chromosome abnormalities were consistently found, indicating that progression of the tumor was clonal. The newly observed clonal aberrations were considered secondary in nature. A relationship between craniocerebral irradiation and development of brain tumors has been reported in several studies, but the mechanism for tumor induction has not yet been elucidated. It is important that the role of radiation therapy in the evolutionary process of chromosomal changes be studied in a large group of similar cases.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
10/22. Diffuse lymphangioma with intrathoracic involvement.A case of a young girl with oligosymptomatic multiple cystic lesions of the chest is presented. The chest lesions were found on routine chest X-ray when she was admitted because of meningococcal meningitis. As the lesions increased in size, surgery was performed; the operative specimens were identified as lymphangioma. This is a rare disorder, which presents difficulties in diagnosis and treatment. Its benign nature is challenged by its tendency to recur and the need for repeated operations.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
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