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1/6. Toxic shock syndrome following cessation of prophylactic antibiotics in a child with a 2% scald.

    Toxic shock syndrome (TSS) is a rare but serious complication of burns in children. Symptoms usually start within 3 days of the burn injury and even children with minor burns can be susceptible. Prompt diagnosis and rapid treatment is crucial in limiting the morbidity associated with this condition. We report here a 19-month-old child with a 2% scald who developed TSS following cessation of a 5-day course of flucloxacillin. This case highlights a number of issues regarding the use of prophylactic antibiotics and TSS as well as illustrating the continuing need to educate parents concerning the importance of seeking a prompt medical opinion if the child becomes ill following even a minor burn injury.
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ranking = 1
keywords = shock syndrome, shock
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2/6. Toxic shock syndrome occurring in children with abrasive injuries beneath casts.

    Staphylococcal toxic shock syndrome has been reported in a number of nonmenstrual settings, including orthopedic patients with postoperative staphylococcal wound infections. We describe two cases of toxic shock syndrome in children with focal cutaneous staphylococcal infections occurring beneath casts placed for limb immobilization. These cases illustrate a new and potentially hidden site of staphylococcal infection leading to toxic shock syndrome.
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ranking = 3.2029922613205
keywords = toxic shock syndrome, shock syndrome, toxic shock, shock
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3/6. A recalcitrant, erythematous, desquamating disorder associated with toxin-producing staphylococci in patients with AIDS.

    Although staphylococcal infections are common in patients with AIDS, staphylococcal toxin-related disorders have rarely been described. Five cases of a staphylococcal toxin-associated syndrome characterized by prolonged erythema, extensive cutaneous desquamation, hypotension, tachycardia, and multiple organ involvement are described in patients with AIDS. These illnesses were recurrent and recalcitrant with a mean duration of 50 days. Toxic shock syndrome toxin-1-producing staphylococci were isolated from three and staphylococcal enterotoxins B and A from one patient each. Sources of organisms were blood, one patient, and soft tissues and nasal accessory sinuses, two patients each. Three of the five patients died of renal failure and central nervous system abnormalities. One survivor required intubation for respiratory failure. All individuals manifested a marked diminution of CD4 cells. Other laboratory abnormalities included azotemia and prolongation of partial thromboplastin time. oliguria occurred in three patients. Thus, this recalcitrant erythematous desquamative disorder appears to be a variant of staphylococcal toxic shock syndrome in certain subsets of immunocompromised individuals.
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ranking = 1.0009974204402
keywords = toxic shock syndrome, shock syndrome, toxic shock, shock
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4/6. A cluster of blister-associated toxic shock syndrome in male military trainees and a study of staphylococcal carriage patterns.

    In March-April 1985, toxic shock syndrome (TSS) developed in three male military trainees at one base secondary to infected blisters acquired while marching during basic combat training. One trainee died. staphylococcus aureus was isolated from the blisters in all three patients, and the two strains available for testing both produced toxic shock syndrome toxin-1 (TSST-1). A culture survey identified carriage of S. aureus in 44% (145/333) of the trainees; carriage rates did not differ between the company with two ill trainees and a control company. Carriage was more frequent in the nose than foot (41% versus 9%, p less than 0.0001). White trainees were more likely to carry S. aureus than black trainees (47% versus 28%, p = 0.013), although the same proportion of strains was positive for TSST-1 in both races. The two strains obtained from the patients had similar but not identical phage typing patterns, but had identical antibiograms, and neither strain carried any plasmids. Based upon phage typing of the TSST-1 positive S. aureus strains isolated in the study, widespread carriage of the case strain(s) in other trainees was not found nor was clustering noted by barrack room. It is possible that differences in carriage rates may partially explain the low rate of TSS in blacks.
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ranking = 4.8059845226411
keywords = toxic shock syndrome, shock syndrome, toxic shock, shock
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5/6. Toxic shock syndrome associated with poison oak dermatitis.

    Toxic shock syndrome commonly occurs in menstruating women, but it is known to be associated with a variety of staphylococcal infections. We report a case of nonmenstrual toxic shock syndrome in an 11-year-old male who presented with altered consciousness and infected poison oak dermatitis of the feet. This is the first reported case of toxic shock syndrome associated with poison oak dermatitis. The signs and symptoms, laboratory findings, and treatment of toxic shock syndrome are reviewed.
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ranking = 3.4029922613205
keywords = toxic shock syndrome, shock syndrome, toxic shock, shock
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6/6. The human immunodeficiency virus and nonmenstrual toxic shock syndrome: a female case presentation.

    Toxic shock syndrome (TSS) generally is associated with tampon use among menstruating women. Descriptions from the early 1980's detailed this sudden, multisystem, frequently fatal disease. The bacterial agent, staphylococcus aureus produced exotoxins, which were quickly identified as the cause of TSS as well as a host of other systemic, bacterial infections. While S. aureus has become one of the more common bacterial pathogens in patients with Acquired Immune Deficiency syndrome (AIDS), staphylococcal toxin-related disorders rarely have been reported in individuals infected with Human Immunodeficiency Virus (hiv) or individuals diagnosed with AIDS. To date all published cases of TSS attendant with hiv involved homosexual, hemophiliac, or drug injecting male patients. This report describes a woman infected with hiv and diagnosed with the classic array of symptoms found in toxic-shock syndrome, and provides information specific to women and their experience with hiv infection.
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ranking = 3.6039896817607
keywords = toxic shock syndrome, shock syndrome, toxic shock, shock
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