Cases reported "Pruritus"

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1/5. Generalized pruritus without primary lesions. Differential diagnosis and approach to treatment.

    A 65-year-old man presented with recurrent generalized pruritus and excoriations of many years' duration. He had been treated with antihistamines, topical corticosteroids, and antibiotics for secondary wound infections, but improvement was only temporary. He had also been hospitalized for leg ulcers complicated by cellulitis. Examination revealed multiple oval and linear red papules and nodules measuring 0.5 to 2 cm in diameter. Some of the lesions were eroded and had a central crater and yellowish crust. The patient also had hypopigmented linear scars localized to the posterior scalp, neck, upper back, chest, abdomen, arms, and legs with sparing of the middle and lower back (figures 1 and 2). An ulcer measuring 1.5 x 2 cm that was surrounded by indurated skin was present on the medial aspect of his right ankle. The ulcer was partially covered by yellow exudate. There was no evidence of cellulitis. liver enzyme, serum creatinine, and thyrotropin levels, as well as a chest roentgenogram, were normal. Wound cultures for bacteria and fungi were nonsignificant. A punch biopsy from a representative lesion showed an abrupt epidermal defect with sparse superficial lymphocytic infiltrate in the dermis. The patient was admitted to the hospital to isolate him from his home environment. He received a 10-day course of systemic cephalexin, topical clobetasol propionate ointment for the affected skin areas, and oral hydroxyzine for pruritus. Ultraviolet light therapy was instituted once daily and was to continue for 2 months. His lesions had improved moderately by the time he was discharged from the hospital. On follow-up 2 weeks later, his lesions were flat and had resulted in hypopigmented scars. Three months later, however, he had persistent, intense pruritus, and new excoriations had developed on his forearms and back. He improved after receiving treatment with oral doxepin hydrochloride.
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2/5. Household papular urticaria.

    BACKGROUND: Papular urticaria often occurs after bites of insects such as mosquitoes, sandflies, bed bugs and fleas. Multiple bites and local pruritus are characteristic symptoms. Treatment is usually symptomatic and includes antihistamines and corticosteroids. The reappearance of the symptoms can be prevented by successful control of the parasite. OBJECTIVES: To find the causative agent of papular urticaria in afflicted households with involvement of numerous family members, all in a narrow geographic area. patients: We describe the cases of 20 patients belonging to seven families, who presented to the local primary clinic, suffering from papular urticaria. RESULTS: The cat flea, ctenocephalides felis, was the hematophagous insect responsible for all infestations. The pruritus and the papular urticaria were treated symptomatically with calamine lotion, topical corticosteroids or oral antihistamines. All clinical symptoms disappeared within a few weeks after effective control of the parasites by spraying and fumigating the infested locations. CONCLUSIONS: Thorough investigation--including, at times, environmental inspection--is necessary to reach the rewarding discovery of the etiology of household papular urticaria. This condition may arise in other environments of similar character.
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3/5. Pseudo-delusory syndrome caused by Limothrips cerealium.

    BACKGROUND: Limothrips cerealium (or "grain thrips") is an insect of the phylum Arthropoda, known as parasite of plants of the family Gramineae; human infestation is not frequently described in literature. MATERIALS AND methods: We report the case of a 59-year-old female farmer, come to observation because of intense itching and sensation of "walking insects" on her head, with no objective cutaneous signs except lesions due to scratching. After repeated visits, in which negative results of clinical and laboratory tests suggested the diagnosis of "delusory syndrome" (Ekbom's syndrome), we finally isolated on her head some insects, identified by stereomicroscopy as L. cerealium. Careful inspection of the house of our patient allowed us to identify, as possible source of parasites, a wheat field and a deposit of grains used for animal feeding. Temporarily removing the patient from her usual environment resulted in complete clinical resolution. RESULTS: Peculiarity of symptoms caused by this parasite and consequent problems for a correct diagnosis are discussed, as well as possible solutions.
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4/5. pseudomonas folliculitis acquired from a health spa whirlpool.

    Three cases of an unusual pseudomonas skin infection acquired from a health spa whirlpool were reported, and an epidemiologic survey showed 17 additional cases. This dermatosis is characterized by the abrupt onset of urticarial papules and superficial and deep papulopustules that spare only the head and neck and occur eight to 48 hours after using the whirlpool. Cultures from one patient's pustules and from the spa whirlpool environment were positive for P aeruginosa, serotype O-11. The condition cleared in all but one patient, without treatment, within seven to ten days. This patient continues to have recurrent follicular pustules three months after exposure. Samples from whirlpools at six other selected establishments were also positive for P aeruginosa.
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5/5. Low humidity occupational dermatoses.

    Two separate instances of dermatoses associated with low humidity in the working environment are reported. In such cases alternative explanations for the dermatoses are often considered and mistakenly adopted.
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