1/24. melanosis of the prostate gland: report of a case with neoplastic epithelium involvement.Prostate gland melanosis is an uncommon lesion and the precise histogenesis is unclear. Melanin may be found within melanocytes in the prostatic stroma, within prostatic epithelium and, rarely, in both locations. The stromal dendritic cell has been shown to contain premelanosomes and melanosomes suggesting primary melanin production by this cell. The melanogenic potential of prostatic epithelial cells has not yet been conclusively established. An example of prostatic melanosis is presented in which stromal and epithelial components were found. This dual distribution of melanin has been regarded as an indication that melanin in the epithelial cells results from phagocytosis of melanin from stromal melanocytes as a secondary phenomenon. Melanin pigment was identified not only within hyperplastic prostatic epithelium but also was found in the epithelial component of a well differentiated prostatic adenocarcinoma.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
2/24. Wegener's granulomatosis of the prostate gland.Wegener's granulomatosis (WG) is a systemic granulomatous vasculitis affecting medium and small arteries, venules, and arterioles. The upper and lower respiratory tract and kidney are primarily involved. patients with classic WG essentially present with upper airway and pulmonary involvement. Renal disease is common. Involvement of other organ systems is also relatively frequent, most often heart, joints, muscles, eyes, skin, and central and/or peripheral nervous system. We present a patient in whom WG was diagnosed primarily because of prostate involvement. This seems to be a rare manifestation.- - - - - - - - - - ranking = 0.8keywords = gland (Clic here for more details about this article) |
3/24. "Alphabet soup" and the prostate: LUTS, BPH, BPE, and BOO.The patient described, though not typical, is one among many of those of the aging male population in whom their primary care physicians will increasingly diagnose diseases affecting the prostate gland. Primary care physicians then will offer first-line therapy not only for prostatic diseases but also for concurrent sexual and erectile dysfunction. This brief primer for primary care physicians "unscrambles" the alphabet in a "soup" of initialisms and acronyms for lower urinary tract symptoms, benign prostatic hyperplasia, benign prostatic enlargement, and bladder outlet obstruction.- - - - - - - - - - ranking = 0.2keywords = gland (Clic here for more details about this article) |
4/24. coccidioidomycosis of the prostate: a determination of incidence, report of 4 cases, and treatment recommendations.OBJECTIVE: To describe the incidence of coccidioides immitis infection of the prostate gland in an endemic area, to describe four new cases discovered, and to propose treatment recommendations for this diagnosis. methods: The pathology reports of all prostate tissue specimens collected at the arizona health Sciences Center from February 1, 1994 through January 1, 2000 and the Southern arizona veterans' Affairs health Care System from January 1, 1990 through January 1, 2000 were reviewed. RESULTS: A total of 3676 pathology reports were reviewed. Forty-four cases of granulomatous prostatitis were identified (incidence=1.2%). Among these, four cases of C. immitis prostatitis were identified (incidence of granulomatous prostatitis=10%; overall incidence=0.1%). Two cases were found at radical retropubic prostatectomy and two were found on prostate needle biopsy. Five months post-radical prostatectomy one man developed symptomatic coccidioidomycosis and died of complications despite treatment with amphotericin B. Another patient who underwent a radical retropubic prostatectomy was treated with oral fluconazole for 14 months immediately after surgery and had a good response. The remaining two patients received no anti-fungal therapy and are being observed. CONCLUSIONS: coccidioidomycosis of the prostate is rare. However, when identified, the finding should not be ignored. patients with symptomatic coccidioidomycosis require immediate anti-fungal therapy. When the diagnosis is an incidental finding and the patient does not manifest symptoms, the degree of tissue violation involved in making the diagnosis influences the need for treatment. patients with minimal tissue violation (i.e. needle biopsy) can be observed whereas patients with more extensive tissue violation (i.e. prostatectomy) should receive anti-fungal therapy.- - - - - - - - - - ranking = 0.2keywords = gland (Clic here for more details about this article) |
5/24. Coexistence of a hemorrhagic cyst and carcinoma in the prostate gland.This report details a case of prostatic carcinoma coexisting with a hemorrhagic cyst in a 66-year-old man; this combination was a challange for diagnosis and mamagement. The patient presented with lower urinary tract symptoms and a serum prostate-specific antigen (PSA) level of 33.3 ng/ml. magnetic resonance imaging of the prostate showed a cystic mass with soft-tissue density and hemorrhage. Histological examination of the suprapubic prostatectomy specimens showed nodular hyperplasia with focal adenosis, high-grade prostatic intraepithelial neoplasia, a Gleason score of 6 for prostatic carcinoma, and a hemorrhagic cyst which appeared to be nonmalignant. We suggest that elevated serum PSA should raise the suspicion of coexisting malignancy in a hemorrhagic cyst.- - - - - - - - - - ranking = 0.8keywords = gland (Clic here for more details about this article) |
6/24. Malakoplakia of the prostate.Malakoplakia of the prostate is a rarely reported granulomatous inflammatory disorder which may clinically mimic carcinoma of the prostate gland. A case of a 70-year-old man, with long follow-up, is reported. Histologic diagnosis allows for effective antibiotic treatment.- - - - - - - - - - ranking = 0.2keywords = gland (Clic here for more details about this article) |
7/24. Extramedullary hematopoiesis in the prostate.A case of bone marrow myelofibrosis with extramedullary hematopoiesis in the prostate gland is described. This 75-year-old man had an 8-year history of myelofibrosis, massive hepatosplenomegaly, and progressive anemia and a 5-year history of bladder outlet obstruction symptomatology. Transurethral resection of prostate was performed, and light microscopic examination of the prostatic chips revealed a diffuse distribution of atypical megakaryocytes, immature granulocytes, and normoblasts in the prostatic stroma. The prostatic glandular epithelium was uninvolved. Immunostaining for hemoglobin in erythroid precursors and a chloroacetate esterase stain for granulocytic precursors were useful in confirming the diagnosis and in defining the extent of prostatic involvement. Extramedullary hematopoiesis is a rare process in the prostate gland, but it should be included in the differential diagnosis of cellular prostatic stromal lesions, particularly when atypical giant cells are observed.- - - - - - - - - - ranking = 0.6keywords = gland (Clic here for more details about this article) |
8/24. Anaerobic septicemia after transrectal prostatic biopsy.Transrectal biopsy of the prostate resulted in anaerobic septicemia in two patients, despite parenteral gentamicin sulfate prophylaxis. bacteroides fragilis sepsis developed subacutely in one patient having a postbiopsy pelvic abscess. clostridium perfringens sepsis occurred fulminantly in another patient 24 hours after biopsy of a gland extensively involved with adenocarcinoma. These cases indicate a potential hazard of sepsis due to anaerobic contamination with rectal microflora at the time of transrectal prostatic biopsy and the futility of prophylaxis directed only at aerobic bacteria.- - - - - - - - - - ranking = 0.2keywords = gland (Clic here for more details about this article) |
9/24. Prostatic involvement in Wegener's granulomatosis.Wegener's granulomatosis involving the prostate gland is unusual. We report 3 cases of this condition in which typical necrotizing granulomas with vasculitis were seen histologically. These lesions may cause gross hematuria or obstructive voiding, including urinary retention. Management includes prostatectomy when the symptoms are severe but an initial trial of aggressive medical therapy may be successful. Treatment requires a knowledge of the natural history of Wegener's granulomatosis and its usual response to medical therapy.- - - - - - - - - - ranking = 0.2keywords = gland (Clic here for more details about this article) |
10/24. Value of transrectal ultrasonography for diagnosis and treatment of prostatic abscess.A new diagnostic and therapeutic application of transrectal ultrasonography (TR-US) is described. TR-US demonstrated one or more well-defined hypoechogenic areas in the prostate gland of 6 patients who presented with clinical signs of urinary tract infection and had only partial response to antibiotic therapy. The presence of a collection of pus in the prostate was confirmed in 4 of 6 patients by transperineal aspiration guided by TR-US, and by prostatic massage or transurethral prostatectomy in the other 2 patients. ultrasonography also confirmed the resolution of abscesses in 5 patients.- - - - - - - - - - ranking = 0.2keywords = gland (Clic here for more details about this article) |
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