1/5. Early detection of infantile pre-type 1 diabetes case with transient hyperglycemia.The patient was an infant with transient hyperglycemia and decreased endogenous insulin secretion on intravenous glucose tolerance test (IVGTT) with the appearance of IA-2 autoantibodies (IA-2Ab), and we speculated that he was in the prediabetes stage. To our knowledge, this is the first case reported to be diagnosed as type 1 diabetes prior to clinical onset in japan.- - - - - - - - - - ranking = 1keywords = glucose (Clic here for more details about this article) |
2/5. Ocular palsies in children with diabetes mellitus.The findings in three children with ocular palsies are reported in this paper. Two had insulin-requiring diabetes and one demonstrated only an abnormal I.V. glucose tolerance test. In the first patient the condition resolved in four weeks; in the second it had not fully resolved after 21 months, and in the third patient surgery was required for correction after seven months. We suggest that any child who develops a sudden ocular palsy should be examined for diabetes mellitus.- - - - - - - - - - ranking = 1keywords = glucose (Clic here for more details about this article) |
3/5. Nodular glomerulosclerosis in a patient showing impaired glucose tolerance.We report a case showing typical diabetic nodular glomerulosclerosis without retinopathy or other apparent clinical findings of DM except for impaired glucose tolerance. The 57-year-old man had a family history but no personal history of DM. In an extensive examination for DM, the results of funduscopy, daily profile of serum glucose and hemoglobin Alc were entirely within normal limits. However, the oral glucose tolerance test was abnormal. A renal biopsy showed typical nodular lesions (Kimmelstiel-Wilson's lesions). Previously, the interesting feature of transient proteinuria had been recognized. Although hypocellular nodular lesions by light microscopy are characteristic of diabetic nephropathy, renal amyloidosis, carbon disulfide intoxication, multiple myeloma and light chain disease, we concluded that the present lesions had resulted from diabetic nephropathy based on the family history, patient history, impaired glucose tolerance, immunofluorescent findings and electron microscopic observations.- - - - - - - - - - ranking = 8keywords = glucose (Clic here for more details about this article) |
4/5. Transient posterior subcapsular lens opacities in diabetes mellitus.In three patients with transient cataracts the lenticular opacities were feathery in nature, and posterior subcapsular in location. They appeared to emanate from a dense central posterior subcapsular plaque. These opacities were examined with the slit lamp and documented photographically. The onset of cataract was abrupt in all three patients, and resolved over a three- to 36-day period. Two patients had bilateral reversible cataracts, and in one of these patients the lenticular opacities were recurrent. Two of the patients had been taking oral corticosteroids. Temporary cataracts have been previously reported in patients with poor diabetic control. diabetes mellitus had been diagnosed in only one of our patients. Three-hour glucose tolerance testing of the other two patients disclosed mildly increased one-hour blood glucose levels. We believe that reversible lens opacities may occur in subclinical diabetes mellitus with normal or only mildly increased blood glucose levels.- - - - - - - - - - ranking = 3keywords = glucose (Clic here for more details about this article) |
5/5. Induction of glycosuria and hyperglycemia by topical corticosteroid therapy.A patient with psoriasis is described who had an abnormal response to the glucose tolerance test without other evidence of diabetes and then developed postprandial hyperglycemia and glycosuria during a period of topical administration of a corticosteroid cream, halcinonide cream 0.1%, under occlusion. A second patient with a similar glucose tolerance test result showed postprandial hyperglycemia when treated similarly with betamethasone valerate cream 0.1%. Two additional patients with midly abnormal responses to glucose tolerance tests showed no evidence of altered glucose metabolism when treated with halcinonide cream in a similar manner.- - - - - - - - - - ranking = 46.091886415385keywords = glucose metabolism, glucose, metabolism (Clic here for more details about this article) |