1/3. Primary staphylococcal infection and toxic shock syndrome diagnosed by polymerase chain reaction.Primary staphylococcal pneumonia complicated with toxic shock syndrome (TSS) is relatively uncommon in children. staphylococcus aureus exotoxins are thought to function as superantigens, and seem to promote disease manifestations. The identification of staphylococcal toxin genes by polymerase chain reaction (PCR) offers a specific and rapid diagnostic method for TSS. We describe a 7-year-old child with TSS resulting from staphylococcal pneumonia. S. aureus enterotoxins A and B were detected in the sputum of this patient by PCR.- - - - - - - - - - ranking = 1keywords = toxic shock syndrome, shock syndrome, toxic shock, shock (Clic here for more details about this article) |
2/3. life-threatening hemoptysis in adults with community-acquired pneumonia due to Panton-Valentine leukocidin-secreting staphylococcus aureus.Three new consecutive cases of life-threatening hemoptysis in adults with community-acquired pneumonia due to Panton-Valentine leukocidin-secreting staphylococcus aureus are presented, focusing on the particular clinical presentation of this new entity. Between December 1999 and March 2001, three adults aged from 23 to 67 years were admitted to our respiratory intensive care unit for massive hemoptysis and septic shock associated with community-acquired staphylococcus aureus pneumonia. Isolates were sent to the Centre National de Reference des Toxemies Staphylococciques in Lyon, france, where they were found to secrete Panton-Valentive leukocidin. The clinical course was similar in the three patients, with massive hemoptysis and septic shock necessitating mechanical ventilation. Two patients died rapidly; necropsy showed pulmonary vascular necrosis in one of them. The third patient recovered after appropriate antibiotic therapy. Leukocidin/neutrophil interactions in the pulmonary vasculature may cause severe hemoptysis in patients with community-acquired staphylococcus aureus pneumonia secreting Panton-Valentine leukocidin. adult patients with massive hemoptysis and suspected community-acquired pneumonia should receive antibiotic regimens covering staphylococcus aureus.- - - - - - - - - - ranking = 0.015906235418864keywords = shock, septic shock (Clic here for more details about this article) |
3/3. Staphylococcal pneumonia, pneumatoceles, and the toxic shock syndrome.A case of community acquired staphylococcal pneumonia is reported with the unusual complication, in an adult, of multiple pneumatoceles. Recognition of this prevented inappropriate management. The patient also developed the toxic shock syndrome. In contrast to infants with pneumatoceles, recovery of lung function has been poor.- - - - - - - - - - ranking = 1keywords = toxic shock syndrome, shock syndrome, toxic shock, shock (Clic here for more details about this article) |