1/6. Inverted transitional cell papilloma of the uterine cervix.A rare case of inverted transitional cell papilloma of the uterine cervix in a 54-year-old woman is described. A polypoid nodule 8 mm in diameter showed histologic features similar to those of urinary tract inverted papilloma. It contained inverted anastomosing epithelial nests divided by scarce fibrovascular septa. The epithelial nests with peripheral palisading had uniform and oval nuclei with longitudinal grooves and swirling orientation. Significant atypia and mitotic activity were absent. Inside the nests there were foci of intraepithelial glandular metaplasia resembling glandular cystitis of the urinary bladder. MIB-1 index was 6%, and the distribution of MIB-1-positive nuclei was similar to that of immature metaplasia. A recurrence-free follow-up period of 16 months along with a low level of proliferation assessed by histology and immunohistochemistry suggests a benign nature of the lesion. A review of published transitional cell (urothelial) lesions of the female genital tract is added.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
2/6. A rare location of bilateral inverted papilloma of the nose and paranasal sinuses.Inverted papilloma is a rare benign sinonasal tumour, characterized by a potentially invasive nature. The lateral nasal wall represents the most common site of origin, whereas paranasal sinuses are involved by extension quite frequently. In contrast, primary sinus inverted papillomas have rarely been reported. Although the midfacial degloving approach has historically been the procedure of choice, recent technological advances have rendered endoscopic sinus surgery a safe procedure with equivalent success rates and low probability of papilloma recurrence. We present a rare case of bilateral inverted papilloma arising from the sphenoid septum and extending towards both the sphenoid and posterior ethmoid sinuses and the posterior section of both nasal cavities, while it slenderizes the sella turcica by compression and elevates the pituitary gland. The bilateral inverted papilloma was successfully removed with a transnasal endoscopic procedure. There is no evidence of recurrence for a follow up period of 1.5 years postoperatively. We conclude that it is a rare entity, which can be treated successfully with endoscopic sinus surgery in the hands of an experienced otorhinolaryngologist.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
3/6. Denture hyperplasia with areas simulating oral inverted ductal papilloma.Denture hyperplasia is a reactive lesion of the oral mucosa, usually associated to an ill-fitting denture. This lesion is easily diagnosed and in some cases distinct microscopic variations such as osseous, oncocytic and squamous metaplasia may be found. These metaplastic alterations probably are associated with the lymphocytic infiltrate usually present in denture hyperplasia. We present a case of denture hyperplasia containing salivary gland tissue with ductal alterations mimicking an oral inverted ductal papilloma.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
4/6. Inverted ductal papilloma of minor salivary gland: case report with immunohistochemical study and literature review.Inverted ductal papilloma (IDP) is a type of ductal papilloma arising in ducts of minor salivary glands. Very few cases, and no cases in japan, have been reported. Reported herein is a case of IDP with a review of the literature. The patient was a 49-year-old man presenting with a lump in the right buccal mucosa of the premolar area of the mandible. The tumor was excised en bloc after a biopsy diagnosis of IDP. On the surface of the covering epithelium, an opening was seen to be filled with mucinous material. On cut surface the opening led to the tumor cavity. The major portion of the tumor parenchyma was made up of papillary proliferation of basaloid squamous cells. Some crypts, microcysts, and mucous cells were seen. There were no findings suggestive of a malignant tumor. The patient's postoperative course was uneventful and there has been no recurrence after 1 year's follow up. Immunohistochemical analysis of the present case supports the hypothesis that IDP originates from squamous metaplasia and proliferation of minor salivary gland duct cells.- - - - - - - - - - ranking = 3keywords = gland (Clic here for more details about this article) |
5/6. Inverted ductal papilloma of minor salivary glands.Inverted ductal papillomas are rare tumours of minor salivary glands. A case is reported on the lower lip of a 50-year-old man. The tumour showed a characteristic endophytic growth pattern and was composed of bulbous papillary projections of basaloid cells dilating and filling the superficial portion of the excretory duct. Histologically, inverted ductal papillomas resemble the inverted papilloma of the nose and paranasal sinuses, but are completely benign and are not associated with malignant change.- - - - - - - - - - ranking = 2.5keywords = gland (Clic here for more details about this article) |
6/6. Glandular-type inverted papilloma of the prostatic urethra.A case of inverted papilloma of glandular type in the prostatic urethra of a 65 year-old man is reported. The case was asymptomatic and incidentally discovered on histopathologic study of transurethral resection (TUR) specimens from benign prostatic hyperplasia. The literature concerning this rare entity is reviewed and briefly commented.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |