1/10. Odontogenic keratocysts in nevoid basal cell carcinoma (Gorlin's) syndrome: CT and MRI evaluation.We describe the imaging findings in a 13-year-old boy with nevoid basal cell carcinoma syndrome (NBCCS). The initial imaging work-up included plain radiographs and computed tomography (CT) of the facial area and mandible. CT detected large expansile cystic changes on both sides of the body and angle of the mandible. When the patient's condition worsened, magnetic resonance imaging (MRI) was performed to further characterize the nature of the lesions and to rule out intracranial anomalies. We agree with others who have published previous reports that although CT is valuable in elucidating osseous craniofacial anomalies associated with NBCCS, MRI is superior in demonstrating the internal composition and structure of the odontogenic keratocysts that are commonly seen in this syndrome.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
2/10. Glandular odontogenic cyst: case report and review of the literature.Glandular odontogenic cyst (GOC) is a rare developmental cyst of the jaws. It is included in the world health organization (WHO) histologic typing of odontogenic tumors under the terms glandular odontogenic cyst or sialo-odontogenic cyst. The most common site of occurrence is the anterior mandible, and it occurs mostly in middle-aged people. A predilection for men is observed. Clinical findings are not specific, and an asymptomatic swelling is frequently observed. A unilocular or multilocular, well-defined radiolucency is usually seen. The microscopic features of GOC, particularly the morphology of the epithelium, strongly suggest an origin from the remains of dental lamina. GOC has an unpredictable and potentially aggressive nature, which may indicate a high tendency of recurrence. The treatment of choice is still controversial, varying from a curettage to local block excision. A long-term follow-up should be carried out. The aim of this article is to report a case of glandular odontogenic cyst that recurred four times and to emphasize the importance of long-term follow-up. The origin, epidemiology, clinical and radiographic aspects, and treatment of the GOC are also discussed.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
3/10. Squamous-cell carcinoma arising from an odontogenic cyst--the importance of computed tomography in the diagnosis of malignancy.Primary intraosseous carcinoma of the mandible is rare, and when it occurs often arises within or closely associated with an odontogenic cyst. The purpose of this article is to show the role of computed tomography (CT) in the early detection of carcinomatous changes, because of its specificity in establishing the nature of the lesion. An unusual case of a squamous cell carcinoma that arose in an odontogenic cyst is described. The appearance on the panoramic radiograph was suggestive of a benign cystic lesion in the left side of the mandible, but when a CT scan was performed, the appearance of the lesion was compatible with malignancy. Histopathological analysis confirmed the suspicion of a squamous cell carcinoma, but without CT investigation it would be impossible to demonstrate that carcinomatous change had developed from a cystic lesion.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
4/10. Glandular odontogenic cyst. Report of two cases and review of the literature.In 1992, the World Heath Organization recognized a new type of cyst called glandular odontogenic cyst (GOC). Clinically, GOC usually presents as a painless, slow-growing swelling. The radiographic appearance is that of a large, multiloculated, well-defined radiolucency. GOC tends to affect the anterior mandible. The dental profession must be aware of the clinical significance of this lesion. The aggressive nature of the lesion has been reported and at least 25% to 55% recur following curettage. If not treated on time, extensive surgery and alteration of function may result. Two new cases are reported.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
5/10. The recalcitrant keratocyst.The clinical enigma of appropriate management of the odontogenic keratocyst is a continuing controversy. The understanding of the pathology of the lesion has undergone a significant metamorphosis over the past 30 years. Certain research findings with respect to this lesion have set it apart from the classical odontogenic cyst, while histologic and clinical observations have made its behaviour reminiscent of the ameloblastoma. Despite its benign nature, its high recurrence rate begs the question of adequacy of treatment modalities to date. Fascinating theories have been put forward to account for its apparent resistance to conventional cyst therapy. Despite this, however, there is no unanimity as to pathogenesis or correct treatment methods. The case of a large odontogenic keratocyst of the mandible is reported and a detailed narrative of its apparently successful management by relatively conservative means is documented.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
6/10. Botryoid odontogenic cyst.Three previously unreported cases of botryoid odontogenic cyst, one of which recurred 9 years after initial surgical removal, are presented. The botryoid odontogenic cyst has a predilection for occurrence in the mandibular canine-premolar region and in persons over the age of 50 years. Periodic radiographic postoperative evaluations are recommended for these lesions, since the possibility of recurrence might be enhanced by their polycystic nature.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
7/10. Isolated odontogenic keratocyst.Although odontogenic keratocysts are benign they are often locally destructive and tend to recur after conservative surgical treatment. They must therefore be distinguished from other cysts of the jaw. Keratocysts possess outpouchings and microscopic daughter cysts from which recurrences may arise. Histologic examination is essential for diagnosis since the appearances on roentgenograms and at operation usually do not reveal the true nature of the lesion. Since many nondental surgeons and pathologists are unaware of odontogenic keratocysts a case is presented in which surgical treatment was originally conservative and finally relatively radical.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
8/10. Variations in keratinizing odontogenic cysts and tumors.classification of keratinizing odontogenic cysts and tumors is not entirely satisfactory to the clinician and pathologist because many individual cases do not fit precisely into a particular category. This report describes the nature of some of these marginal lesions in order that similar cases may be diagnosed and treated correctly. Eight selected cases are described histologically, and their clinical behavior is discussed. It is concluded that the histopathologic appearance of the odontogenic epithelium in odontogenic cysts and tumors varies to a large extent and gives rise to a variety of keratinizing lesions. It is further concluded that some varieties are unique and, for the present, treatment of the rare lesions depends more on observed clinical behavior, with morphology having a lesser role in prognosis. It is important that clinicians as well as pathologists be aware of the wide variation of these keratinizing lesions so that the patient will receive optimum treatment.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
9/10. Glandular odontogenic cysts. diagnosis and treatment.Four cases of glandular odontogenic cyst are reported. review of these and 13 previously reported cases indicates that they present as slowly growing, painless, radiolucent swellings with a predilection for the anterior part of the mandible. An incisional biopsy is essential to establish a definitive preoperative diagnosis. The unpredictable and potentially aggressive nature of these lesions is suggested by their extensive nature, penetration of cortical bone, locally invasive potential, and high incidence of recurrence after conservative treatment. In view of this behavior we suggest en bloc excision and primary reconstruction to ensure cure and reduce the operative morbidity.- - - - - - - - - - ranking = 2keywords = nature (Clic here for more details about this article) |
10/10. Penetration of the skull base by dissecting keratocyst.The extensive destructive potential of the keratocyst has been well recognized but penetration of the keratocyst into the skull base is rare. 3 cases showing such aggressive behavior and rare location were seen and treated; 2 are reported in this paper. Both cases illustrate the importance of early radical treatment once the aggressive nature of keratocyst is recognized.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
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