1/412. Pulmonary tuberculosis following successful treatment of pulmonary infection with mycobacterium kansasii.A case of pulmonary tuberculosis following successful treatment of pulmonary infection with mycobacterium kansasii is presented. The immunizing effect of an infection with M kansasii and and other nonspecific immune factors are discussed.- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
2/412. Lymphocyte transformation test for the evaluation of adverse effects of antituberculous drugs.The usefulness of the lymphocyte transformation test (LTT) for the analysis of adverse reactions to antituberculous drugs was evaluated. - The LTT was performed with isoniazid and rifampicin in 15 tuberculosis and 2 MOTT (Mycobacteria other than tuberculosis)-infection patients who suffered drug reactions, in 23 patients without any adverse reactions, in 7 controls previously exposed to antituberculous drugs, and in 14 controls who had never been exposed. 4/15 of the hepatotoxic reactions only showed a positive LTT with rifampicin, 3/15 only with isoniazid, and in 8/15 the LTT was negative. In an anaphylactoid shock reaction the LTT was extremely exaggerated for both rifampicin and isoniazid. In patients without any side effects only one slightly increased LTT due to isoniazid was observed. Two healthy controls with previous contact to these drugs showed a positive LTT for isoniazid, one of those with both rifampicin and isoniazid. The LTT was negative in all control persons without any former contact to antituberculous medications. In most cases hepatotoxicity seems to be a pure toxic reaction without the participation of cellular immune mechanisms. LTT can be useful for identifying the drug responsible for immunological side effects.- - - - - - - - - - ranking = 0.16666666666667keywords = infection (Clic here for more details about this article) |
3/412. Flexor tenosynovitis in the hand caused by Mycobacterium terrae.The authors describe an uncommon case of flexor tenosynovitis caused by Mycobacterium terrae, an atypical mycobacterium generally considered nonpathogenic in humans. A prolonged delay in diagnosis and various ineffective therapies led to synovial biopsy and culture. After confirming the diagnosis of M. terrae, appropriate antimycobacterial chemotherapy resolved the synovitis. For chronic tenosynovitis without a clear etiology, limited synovectomy and culture are essential in establishing a diagnosis and in initiating treatment for this atypical mycobacterial infection.- - - - - - - - - - ranking = 0.16666666666667keywords = infection (Clic here for more details about this article) |
4/412. Acquired resistance to rifampicin by mycobacterium kansasii.Two patients with mycobacterium kansasii infection of the lung had organisms sensitive to rifampicin. Following treatment, essentially with rifampicin alone, the patients began to excrete organisms completely resistant to rifampicin. The ability of M. kansasii to acquire resistance to rifampicin during treatment has been clearly demonstrated. This reinforces the need to treat this infection with an adequate multiple drug regimen.- - - - - - - - - - ranking = 0.33333333333333keywords = infection (Clic here for more details about this article) |
5/412. mycobacterium fortuitum spinal infection: case report.Acute paraplegia followed a vertebral infection with mycobacterium fortuitum. There was a satisfactory response to surgery and antibiotics. No predisposing factors for this primary bone infection could be found.- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
6/412. mycobacterium marinum infection from a tropical fish tank. Treatment with trimethoprim and sulphamethoxazole.A paronychial granuloma on the left thumb, in a man who kept tanks of tropical fish, was followed by cutaneous nodules on the left upper limb and tender lymph nodes in the left axilla. mycobacterium marinum was isolated from the lesion on the thumb and also from the tank water. Subsidence of the lesions followed administration of trimethoprim and sulphamethoxazole.- - - - - - - - - - ranking = 0.66666666666667keywords = infection (Clic here for more details about this article) |
7/412. Mycobacterial central venous catheter tunnel infection: a difficult problem.We report our experience of non-tuberculous mycobacterial infection associated with the tunnel of Hickman-Broviac central venous catheters in immunosuppressed patients with haematological malignancies undergoing high-dose chemotherapy supported by BMT. The problem is rare and difficult to treat. Our cases are unique in developing tunnel site mycobacterial infection well after the tunnelled catheters were removed. We diagnosed one case of mycobacterium chelonae, which is a well-documented cause of such infections, and two cases of mycobacterium haemophilum, which are the first reported cases in this setting. Early wide surgical excision of the infected tunnel site and prolonged antibiotic therapy is necessary. Despite these measures recurrence occurred in two cases. Close liaison with the microbiology laboratory is needed to ensure the appropriate culture media and conditions are used for these fastidious organisms. Empiric antibiotic regimens should be based on the likely organism. Drugs active against M. chelonae and M. haemophilum should be included.- - - - - - - - - - ranking = 1.1666666666667keywords = infection (Clic here for more details about this article) |
8/412. Mycobacterium malmoense infections in immunocompetent patients.While Mycobacterium malmoense infections were originally restricted to northern europe, there has been an increasing number of reports of cases of infection in other countries. Two cases of infections due to Mycobacterium malmoense in immunocompetent patients in germany are presented. In both cases a presumptive diagnosis of tuberculosis was established initially. Mycobacterium malmoense was cultured after a long incubation period (6-8 weeks). The patients were successfully treated with a triple regimen consisting of rifampicin, ethambutol and clarithromycin. The epidemiology and difficulties in diagnosis of Mycobacterium malmoense infection are discussed.- - - - - - - - - - ranking = 1.3333333333333keywords = infection (Clic here for more details about this article) |
9/412. Tuberculous cellulitis in a child demonstrated by magnetic resonance imaging.The increasing prevalence of extrapulmonary tuberculosis means that it is important for clinicians to review their knowledge of unusual presentations of mycobacterial infections. Involvement of subcutaneous tissue and skeletal muscle is rare in tuberculosis. Occasionally, infection of soft tissue may be the sole manifestation of tuberculosis. Apart from cases of tuberculous lymphadenitis, the diagnosis of extrapulmonary tuberculosis may be difficult. Modern imaging techniques, such as magnetic resonance imaging, may be helpful in making a differential diagnosis. We present here a case of tuberculous cellulitis in an immunocompetent child and discuss the contribution of MRI in diagnosis.- - - - - - - - - - ranking = 0.33333333333333keywords = infection (Clic here for more details about this article) |
10/412. Localized primary cutaneous mycobacterium kansasii infection in an immunocompromised patient.mycobacterium kansasii is a rare primary cutaneous pathogen, most commonly affecting persons exposed to contaminated water, particularly after local trauma. Most patients who present with localized primary cutaneous M kansasii infection are immunocompetent, whereas the majority of patients with disseminated or pulmonary infection are immunocompromised. We describe a primary cutaneous M kansasii infection in an iatrogenically immunosuppressed patient.- - - - - - - - - - ranking = 1.1666666666667keywords = infection (Clic here for more details about this article) |
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