1/25. mycobacterium fortuitum endocarditis and meningitis after balloon mitral valvotomy.Mycobacteria rarely cause endocardial infections. We describe the clinical course of a patient who developed endocarditis, and meningitis with mycobacterium fortuitum following balloon mitral valvotomy. The patient was treated with amikacin and clarithromycin but did not respond. She developed haemolytic anaemia as the terminal event.- - - - - - - - - - ranking = 1keywords = bacterium (Clic here for more details about this article) |
2/25. pasteurella multocida meningitis in an adult: case report.pasteurella multocida is known to form part of the normal flora in the nasopharynx or gastrointestinal tract in many domestic and wild animals. Most human P multocida infections are soft tissue infections caused by dog or cat bites. Less commonly this bacterium is associated with infections affecting other organ systems of man. A case of fatal P multocida meningitis discovered at the necropsy of a 52 year old man is described. P multocida is an unusual causative agent of meningitis which tends to affect those at the extremes of age.- - - - - - - - - - ranking = 0.2keywords = bacterium (Clic here for more details about this article) |
3/25. Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.We report a case of posttraumatic meningitis due to Mycobacterium abscessus, treated initially with oral clarithromycin and intravenous amikacin plus intrathecal amikacin. Despite cerebrospinal fluid (CSF) levels of clarithromycin and amikacin in excess of their in vitro minimum inhibitory concentrations for the organism, the CSF cultures remained continuously positive for M. abscessus. To our knowledge, this is the first documented case of M. abscessus meningitis and the first report of measured CSF levels of clarithromycin in a patient with meningitis, showing that even therapeutic CSF levels of clarithromycin and amikacin might not be successful in eradicating M. abscessus meningitis.- - - - - - - - - - ranking = 1keywords = bacterium (Clic here for more details about this article) |
4/25. streptococcus bovis meningitis in a neonate with Ivemark syndrome.Although streptococcus bovis infections in adults are associated with endocarditis and bowel neoplasms, S. bovis-associated meningitis is rare in neonates. We describe the case of a neonate with Ivemark syndrome, which possibly predisposed her to infection with this bacterium.- - - - - - - - - - ranking = 0.2keywords = bacterium (Clic here for more details about this article) |
5/25. enterobacter sakazakii infections associated with the use of powdered infant formula--tennessee, 2001.enterobacter sakazakii, a gram-negative, rod-shaped bacterium, is a rare cause of invasive infection with high death rates in neonates. This report summarizes the investigation of a fatal infection associated with E. sakazakii in a hospitalized neonate, which indicated that the infection was associated with the presence of the organism in commercial powdered formula fed to the infant. The implicated batch of formula has been recalled by the manufacturer. Clinicians should be aware of the potential risk for infection from use of nonsterile enteral formula in the neonatal health-care setting.- - - - - - - - - - ranking = 0.2keywords = bacterium (Clic here for more details about this article) |
6/25. Sensorineural hearing loss associated with intrathecal vancomycin.OBJECTIVE: To report a case of nonreversible bilateral sensorineural hearing loss resulting from administration of intrathecal vancomycin. CASE SUMMARY: A 63-year-old white man with newly diagnosed pre-B-cell acute lymphocytic leukemia developed corynebacterium jeikeium meningitis associated with an Ommaya reservoir. The patient was treated with intravenous vancomycin for several days without symptomatic improvement, and intrathecal vancomycin was added to the treatment regimen. Difficulty in the patient's hearing was noted after the first intrathecal dose and he experienced complete hearing loss after the second intrathecal dose. An audiogram was performed and the patient was diagnosed with cranial nerve VIII bilateral sensorineural hearing loss. The Ommaya reservoir was removed and the patient was successfully treated with linezolid. DISCUSSION: Ototoxicity with intravenous vancomycin has been documented in multiple case reports, but this adverse effect has not been reported with intrathecal vancomycin. cerebrospinal fluid vancomycin concentrations were not measured in our patient, but there was 1 documented occurrence of supratherapeutic serum vancomycin concentrations. Other drug-related causes of ototoxicity were evaluated and intrathecal vancomycin-induced ototoxicity was considered to be possible according to the Naranjo probability scale. CONCLUSIONS: The strong temporal relationship that was seen in this case suggests the possibility of an association between administration of intrathecal vancomycin and hearing loss. Healthcare providers should consider the potential for this adverse reaction with the intrathecal route of vancomycin administration.- - - - - - - - - - ranking = 0.2keywords = bacterium (Clic here for more details about this article) |
7/25. Cerebral infarct and meningitis secondary to Lemierre's syndrome.The case is reported of a young man with fusobacterium necrophorum septicemia who developed cavernous sinus thrombosis, meningitis, carotid artery stenosis and stroke. This article presents the only reported case of arterial stroke in Lemierre's syndrome. Clinical presentation, diagnostic difficulty and treatment are discussed.- - - - - - - - - - ranking = 0.2keywords = bacterium (Clic here for more details about this article) |
8/25. Otogenic Fusobacterium meningitis, sepsis, and mastoiditis in an adolescent.fusobacterium necrophorum is a strict anaerobic organism responsible for a number of clinical syndromes known as necrobacillosis. Although meningeal infections with anaerobes are rare, delayed diagnosis and treatment can be potentially fatal. We report a unique case of Fusobacterium meningitis, mastoiditis, and sepsis in a previously healthy adolescent. Diagnosis and management of this condition are discussed in the context of a literature review.- - - - - - - - - - ranking = 1.2keywords = bacterium (Clic here for more details about this article) |
9/25. meningitis due to fusobacterium necrophorum in an adult.BACKGROUND: fusobacterium necrophorum may cause a number of clinical syndromes, collectively known as necrobacillosis. meningitis is a significant cause of mortality, rarely reported in the adult population. CASE PRESENTATION: We report a fatal case of meningitis, caused by fusobacterium necrophorum, secondary to otitis media in an alcoholic male. Diagnosis was delayed due to the typical slow growth of the organism. The clinical course was complicated by encephalitis and by hydrocephalus. The patient failed to respond to metronidazole and penicillin. The patient died on day 12 from increased intracranial pressure and brain stem infarction. CONCLUSIONS: This case emphasizes the need for a high index of clinical suspicion to make the diagnosis of fusobacterium necrophorum meningitis. We recommend the use of appropriate anaerobic culture techniques and antimicrobial coverage for anaerobic organisms when the gram stain shows gram negative bacilli.- - - - - - - - - - ranking = 1.4keywords = bacterium (Clic here for more details about this article) |
10/25. An adult case of chryseobacterium meningosepticum meningitis.chryseobacterium meningosepticum is an uncommon pathogen causing adult bacterial meningitis. Herein, we report the case history of one 21-year-old woman with this uncommon central nervous system infection. A diagnosis of adult C. meningosepticum meningitis can only be confirmed by a positive cerebrospinal fluid (CSF) culture. The patient had insulin-dependent diabetes mellitus as the underlying condition associated with this infection. The clinical presentations were fever, headache, consciousness disturbance, and seizure. CSF analysis revealed a purulent inflammatory reaction. After a 21-day course of intravenous cefepime (6 g/day) treatment, this patient was discharged in a state of complete recovery.- - - - - - - - - - ranking = 1keywords = bacterium (Clic here for more details about this article) |
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