Cases reported "Melioidosis"

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1/6. Cutaneous melioidosis.

    melioidosis is a rare tropical disease caused by infection with the bacterium burkholderia pseudomallei. It occurs predominantly in south-east asia, northern and central australia and central and south america. patients often present to the internal medicine physicians with a severe, potentially fatal sepsis. We report three patients who presented to our dermatology department with cutaneous melioidosis.
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2/6. melioidosis complicated by pericarditis.

    A case of acute and recrudescent melioidosis complicated by pericarditis and pericardial effusion is described. The potential for the appearance of future cases in the united states and the necessity for physicians to remain aware of this potential diagnosis are discussed.
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3/6. Computed tomography characteristics of burkholderia pseudomallei liver abscess.

    We report 3 cases of burkholderia pseudomallei liver abscesses that have a characteristic "honeycomb" appearance on computed tomography scans. Such a finding should prompt physicians to include B. pseudomallei infection in the differential diagnoses of liver abscesses and consider initiation of empirical therapy for melioidosis in high-risk patients from areas of endemicity.
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4/6. Septicemic melioidosis. Occurrence following acute influenza A six years after exposure in vietnam.

    Septicemic melioidosis in association with acute influenza A was diagnosed in a vietnam veteran. The case illustrates that activation of melioidosis can occur long after exposure to a known endemic area and may be precipitated by infections with other common pathogens. Hence, physicians must maintain a high index of suspicion of melioidosis when dealing with unexplained sepsis in vietnam veterans. Prolonged therapy with appropriate antimicrobial agents is needed to eradicate this infection.
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5/6. Meliodosis.

    During the five-month wet season of 1977-1978 in Northern queensland, six patients with bacteriologically proven melioidosis were successfully treated at the Townsville General Hospital, The clinical course and management of each case and laboratory findings are described. Factors which predisposed them to infection with pseudomonas pseudomallei were diabetes mellitus, cancer, alcoholism, malnutrition, trauma, and pregnancy. Successful treatment of melioidosis relied on prompt laboratory diagnosis and appropriate chemotherapy together with surgical drainage of abscesses and management of concomitant diseases. The incidence of melioidosis in Northern queensland has increased to the extent that it can no longer be considered a rare disease in this area. Because of increased internal and international travel, and displacement of refugees from endemic areas of Southeast Asia, physicians and microbiologists must maintain a high index of suspicion of melioidosis when dealing with patients after geographic exposure, as it is probable that, in the future, this disease witll be encountered more frequently in non-endemic areas.
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6/6. melioidosis: two indigenous cases in taiwan.

    We report the first two indigenously acquired cases of melioidosis in taiwan, diagnosed by positive culture and biochemically identified using the ID 32 GN system (BioMerieux Vitek Inc, Hazelwood, MO, USA). The first patient was a 75-year-old Chinese woman who had not travelled abroad since her arrival from mainland china (San-Tung province) 47 years ago. She presented with spontaneous bacterial peritonitis and hepatitis c-related liver cirrhosis with septic shock. burkholderia pseudomallei (formerly pseudomonas pseudomallei) was isolated from cultures of both blood and ascites fluid. The second patient, a 70-year-old Chinese man, presented with right lower lobar pneumonia complicated with empyema and septic shock. blood cultures grew B. pseudomallei. Both patients had underlying diabetes mellitus; one also had liver cirrhosis and chronic renal failure, while the other had a renal stone. The first patient died of refractory septic shock prior to diagnosis. The second patient survived with the use of intravenous ceftazidime for 30 days, followed by oral amoxicillin-clavulanic acid for a further 3 months. These cases serve as a reminder to clinical physicians that melioidosis is now no longer exclusive to patients with a history of travel to endemic areas. A high index of clinical suspicion is required for early diagnosis and treatment in order to reduce the mortality and improve clinical outcome.
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