1/6. First report of an isolated jejunal seminoma: presentation with melaena and iron deficiency anaemia.We present the case history of a man with isolated seminoma in the jejunum and abnormal testes but no provable malignant testicular disease. Treatment with cisplatin-based chemotherapy led to complete resolution of the jejunal seminoma. The rarity of seminoma involving the small bowel is highlighted. A literature search did not reveal other similar cases of isolated seminoma affecting the jejunum. The possible origins of this tumour are discussed.- - - - - - - - - - ranking = 1keywords = anaemia (Clic here for more details about this article) |
2/6. Blue rubber bleb nevus syndrome and gastrointestinal haemorrhage: which treatment?PURPOSE: To describe a paediatric case of "Blue rubber Bleb nevus syndrome" (BRBNS) or Bean's syndrome, a rare systemic disorder characterised by cutaneous and gastrointestinal vascular malformations that often lead to overt life-threatening gastrointestinal bleeding or occult blood loss with severe anaemia and iron deficiency. CASE REPORT: A 6-year-old girl with multiple characteristic cutaneous vascular lesions was admitted for a massive rectal bleeding. A few months previously she was endoscopically treated for gastric angiomas which developed into melaena. Preoperative investigations revealed the recurrence of gastric lesions. At laparotomy, more than 25 angiomas of the GI tract were found. Multiple intestinal resections were carried out. RESULTS: No intraoperative or postoperative problems occurred and the girl is completely healthy without further bleeding after a follow-up period of three years. CONCLUSIONS: BRBNS belongs to the group of vascular venous malformations. Most of the time it occurs sporadically, but it can be inherited as an autosomal dominant trait. Recent analysis identified a locus on chromosome 9 responsible for venous malformations. BRBNS patients present typical skin lesions, with some lesions having a rubber-like nipple appearance; the number of skin and GI lesions and the severity of anaemia are correlated. Treatment is dependent on the extent of gut involvement and the severity of the clinical picture. In the absence of massive bleeding, a conservative treatment will be sufficient; otherwise resections are mandatory, but additional lesions may subsequently develop. Management with electrocautery or laser photocoagulation are usually not effective even if some reports recommend them. Pharmacological treatment is useless. prognosis of BRBNS is unknown.- - - - - - - - - - ranking = 0.5keywords = anaemia (Clic here for more details about this article) |
3/6. Melaena as the presenting symptom of gastric mucosal injury due to blunt abdominal trauma.Blunt abdominal trauma is a common cause of admission to the typical trauma centre. Hollow viscus injury from blunt trauma, however, is unusual and rarely involves the stomach. A 15 year old boy sustained a bicycle handle bar injury to the abdomen and presented to the casualty department four days later with melaena. A computed tomography (CT) scan of the abdomen showed normal findings but endoscopy revealed two "kissing" areas of mucosal ulceration on the anterior and posterior wall of the gastric antrum. The patient received a blood transfusion for anaemia but was otherwise treated conservatively and made a full recovery. The authors believe this to be the first reported case of melaena as the primary presenting symptom of gastric ulceration secondary to blunt abdominal trauma. diagnosis of hollow viscus injuries due to blunt abdominal trauma requires a high index of suspicion and thorough investigation, particularly if the presentation is delayed.- - - - - - - - - - ranking = 0.25keywords = anaemia (Clic here for more details about this article) |
4/6. Small bowel melaena: 2 cases diagnosed by angiography.Two cases of small bowel tumour presenting with melaena are reported. Selective visceral arteriography was found to be invaluable in the management of these cases. The first case presented with intermittent bleeding causing anaemia. Conventional barium studies of the small and large bowel revealed no abnormality. Superior mesenteric angiography revealed a mass lesion in the jejunum, with features characteristic of a leiomyoma. The second case presented with massive gastrointestinal bleeding. Selective visceral angiography was performed initially and revealed a large, mainly avascular, mass lesion in the ileum. Pathological examination showed a leiomyoma which had undergone cystic degeneration. The value of selective angiography in patients with suspected small bowel bleeding is discussed..- - - - - - - - - - ranking = 0.25keywords = anaemia (Clic here for more details about this article) |
5/6. Recurrent intestinal haemorrhages caused by a lipoma in the ileocaecal valve in a patient with Von Willebrand's disease.Lipomas of the digestive tract are rare and may give rise to obstruction, intussusception or haemorrhage. In a 74-year old woman with Von Willebrand's disease, a lipoma in the ileocaecal valve caused frequent intestinal haemorrhages and chronic anaemia over a period of more than 15 years. diagnosis and therapy are discussed on the basis of the case history.- - - - - - - - - - ranking = 0.25keywords = anaemia (Clic here for more details about this article) |
6/6. leiomyoma of the small intestine in an 11-year-old boy.A case is reported of anaemia in an 11-year-old boy due to an ileal leiomyoma, a very rare tumour in the paediatric age group.- - - - - - - - - - ranking = 0.25keywords = anaemia (Clic here for more details about this article) |