Cases reported "Mandibular Neoplasms"

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1/28. Intraosseous neurofibroma of the jaws.

    Two cases of intraosseous neurofibromas of the mandible are presented. Only 25 cases of this tumor have been published previously. Of the present two cases, one was located at the upper border of the mandible, in the left second molar area where the tooth had been extracted 2 years previously. In the second case, the tumor presented itself as a 10 x 2 cm large destruction, mainly following the course of the alveolar nerve from the mandibular foramen to the mental foramen in the right side of the jaw. The mandibular first right molar was missing but the relationship between the extraction of the tooth and the development of the tumor could not be demonstrated. Histologically, the two tumors differed in the way that case 1 showed a conspicuous amount of delicate, wavy fibrils, some of which showed concentric lamellations resembling the pacinian corpuscle but without neurites containing nerve fiber bundles and also demonstrated a slight pleomorphism.
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2/28. Primary intraosseous carcinoma of the mandible with probable origin from reduced enamel epithelium.

    This report describes a case of primary intraosseous carcinoma (PIOC) arising de novo in the mandible. The patient was a 74-year-old woman and an early PIOC was found incidentally during histopathological examination of the pericoronal tissue obtained at extraction of a deeply impacted third molar. The curetted soft tissues consisted of a microinvasive, keratinizing squamous cell carcinoma with scattered foci of carcinoma cells showing calcification; stromal osseous metaplasia was also observed. After additional treatment, the patient has remained free of disease for 2 years. Since the tumor was completely enclosed in the bone, the only identifiable source of the present PIOC is the reduced enamel epithelium. Despite its rarity, this case emphasizes the importance of careful histologic examination of all apparently innocuous dental follicles that are removed surgically.
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3/28. Cemento-ossifying fibroma presenting as a mass of the parapharyngeal and masticator space.

    We report a case of cemento-ossifying fibroma that presented as a large extraosseous mass in the masticator and parapharyngeal space. CT scanning and MR imaging showed a large extraosseous mass with central conglomerated, well-matured ossified nodules and fatty marrow. The central matured ossified nodules were of low density on CT scans and high signal intensity on T1- and T2-weighted MR images. Multiplanar reformatted CT scans revealed the origin of the mass to be at the extraction site of the right lower second molar tooth.
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4/28. Parosteal osteogenic sarcoma of the mandible, Existence masked by diffuse periodontal inflammation.

    A 38-year-old man was in a state of poor oral hygiene, with multiple broken carious teeth and diffuse inflammatory hyperplasia of the gingival tissues. A mandibular, alveolar soft tissue mass in the premolar-molar region was noted on the right side, in continuity with the gingival hyperplasia. biopsy of the lesion ruled out a diagnosis of squamous cell carcinoma. The patient underwent extraction of his teeth, and all hyperplastic tissues including the tumefaction were excised. Five months later, the patient had a recurrent mass in the same location that was removed via hemimandibulectomy. The mass was diagnosed as a parosteal osteogenic sarcoma.
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5/28. Dental blood supply in the segmentally resected mandible.

    There are approximately 30,000 new cases of oral and pharyngeal carcinoma treated in the united states each year. A large number of these patients go on to receive segmental resection of the mandible, and have natural teeth remaining on the surgical side. To the best of our knowledge, there has not been a thorough discussion of the blood supply to these remaining teeth. Radiographic evidence of periapical pathology in these teeth is unusual, despite the compromised vascular supply. The purpose of this article is to report a case and review the literature on blood supply to teeth after segmental mandibulectomy. Microscopic examination was conducted on the pulpal tissue of a premolar retained on the side of, and anterior to, a segmental mandibular resection. Although abnormal, the pulp tissue showed evidence of a vascular supply 4 yr after mandibular surgery. A literature review was performed, and a discussion is given to explain the continued vascularity of the dentition through collateral and retrograde circulation. Despite the compromised dental circulation on the surgical side, unless radiographic evidence of periapical pathology occurs, endodontic therapy or extraction is not necessary. Due to the compromised nature of the circulation however, these teeth may be more susceptible to caries or restorative dental procedures that may lead to pulpal necrosis.
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6/28. Primary non-Hodgkin's lymphoma of the mandible presenting following tooth extraction.

    A case of oral non-Hodgkin's lymphoma presenting following a tooth extraction is reported. The clinical presentation was that of a periodontal lesion and an extraction socket that failed to heal, which may have led to initial confusion in diagnosis and management.
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7/28. Intra-alveolar granulocytic sarcoma developing after tooth extraction.

    Granulocytic sarcoma (GS) is a malignant tumour composed of poorly differentiated myeloid cells forming in an extramedullary site. It is generally associated with acute leukaemia, particularly the myelocytic type. Its appearance in patients with chronic myeloid leukaemia is exceptional. GS can appear in multiple locations with the oral cavity being rarely involved. A mandibular GS detected in a patient with chronic myeloid leukaemia 10 days after a tooth extraction is reported. The pathogenesis (by metastatic cells or migration through the Haversian canals) of the tumour is discussed.
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8/28. Calcifying epithelial odontogenic (Pindborg) tumor with malignant transformation and metastatic spread.

    BACKGROUND: Pindborg tumors (calcifying epithelial odontogenic tumors) are uncommon neoplasms of odontogenic origin most often located in the posterior mandible. First described in detail in 1955 by Pindborg, these tumors are considered benign but can be locally aggressive in nature, with recurrence rates of 10% to 15% reported. The malignant form of this tumor is exceedingly rare. methods: We describe the case of a 64-year-old woman initially treated for a painful infected left mandibular third molar. The patient underwent extraction of the tooth and excision of an associated soft tissue component. Subsequent histologic review identified a Pindborg tumor of the left posterior mandible. RESULTS: After initial excision, this tumor recurred twice, with the recurrences exhibiting a progression to a malignant Pindborg tumor (odontogenic carcinoma) with vascular invasion and spread to a cervical lymph node. Further treatment involved radical surgery and adjuvant radiotherapy. At last review 12 months after treatment, the patient was disease free. CONCLUSIONS: This article describes only the second case of odontogenic carcinoma. The transformation from benign to malignant histologic findings has not previously been documented in this tumor. The salient clinical features of this case are presented along with supportive pathologic and radiologic evidence.
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9/28. multiple myeloma presenting as a painful mandibular swelling: a case report.

    multiple myeloma is a disease characterized by monoclonal proliferation of plasma cells, the most differentiated stage of B-cells. Primary manifestation of multiple myeloma in the jawbones is rare. In the case reported here, a 29-year-old woman who presented with a right mandibular swelling after extraction of a mobile painful tooth turned out to have multiple myeloma. Current diagnostic criteria and management strategies of the disease are discussed.
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10/28. Ultrasound features of osteosarcoma of the mandible--a first report.

    Ultrasound imaging is becoming widely used in the head and neck region as a first-line investigation to assess soft tissue swellings. Clinicians should be aware of the potential of diagnostic ultrasound to identify important signs of malignant disease involving bone.Involvement of the mandible by osteosarcoma is uncommon. A young adult patient presented with facial swelling and an apparently infected lower third molar extraction socket. Subtle signs were missed on dental radiographs. Diagnostic ultrasound investigation was pivotal in identifying sinister signs: namely, soft tissue mass associated with bone thinning, erosion, expansion, and the "sunray" appearance of the buccal cortex, which were suggestive of osteosarcoma. These findings enabled priority to be given to subsequent investigations using other modalities. We present a first report of the ultrasound features of osteosarcoma of the mandible and consider this to be a useful modality in an initial investigation.
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