1/15. Metastatic unknown primary tumor presenting in pregnancy as multiple cerebral infarcts.BACKGROUND: Cancer presenting during pregnancy is a rare event. There are no reports of an unknown primary tumor presenting during pregnancy. CASE: A 35-year-old primigravida presented at 16 weeks' gestation with multiple cerebral infarcts. After a negative workup she was discharged on anticoagulation therapy, only to return at 29 weeks with diffuse, metastatic cancer of unknown primary origin. After an elective 32-week delivery she received aggressive chemotherapy but ultimately died 5 months later. CONCLUSION: Malignancy should be included in the differential diagnosis of unusual, unexplained cases of thromboembolism in pregnancy.- - - - - - - - - - ranking = 1keywords = pregnancy (Clic here for more details about this article) |
2/15. Cerebral venous thrombosis: new causes for an old syndrome?The range of disorders affecting the cerebral veins and sinuses is increasing and now includes blood disorders, abnormalities in the patterns of blood flow, and infiltrative or inflammatory conditions, all of which may promote thrombosis. We describe 10 patients with cerebral venous thrombosis: two had protein s deficiency, one had protein c deficiency, one was in early pregnancy, and there was a single case of each of the following: dural arteriovenous malformation, intracerebral arteriovenous malformation, bilateral glomus tumours, systemic lupus erythematosus, Wegener's granulomatosis, non-Hodgkin's lymphoma. The recognition of such diverse aetiology may be importance since clinical features are non-specific, and may consist only of raised intracranial pressure, allowing confusion with 'benign intracranial hypertension'. The existence of effective treatment both for the thrombosis and for many of the underlying disorders makes early diagnosis essential. The prognosis of treated patients may be favourable.- - - - - - - - - - ranking = 0.14285714285714keywords = pregnancy (Clic here for more details about this article) |
3/15. Successful pregnancy in a patient with paroxysmal nocturnal hemoglobinuria: case report.In this report, the maternal and fetal risks in a patient with paroxysmal nocturnal hemoglobinuria (PNH) were evaluated. A patient with PNH carried a pregnancy to successful delivery, with a healthy male infant, and suffered from postpartum cerebral subcortical thrombosis followed by recovery. An elevated level of serum lactate dehydrogenase isoenzyme (alpha-hydroxybutyrate dehydrogenase) was observed during pregnancy; the level returned to normal by delivery. However, the hemoglobin concentration during pregnancy and post-partum was kept at 8 g/dl. This is the first report of a relation between the onset of hemolysis and pregnancy. The management of pregnancy in such patients is discussed.- - - - - - - - - - ranking = 1.2857142857143keywords = pregnancy (Clic here for more details about this article) |
4/15. cerebrovascular disorders associated with pregnancy.stroke is a leading cause of maternal death. Intracerebral hemorrhage may be associated with eclampsia, metastatic choriocarcinoma or ruptured arteriovenous malformations. Intracranial venous thrombosis may result from a hypercoagulable state or local intracranial vascular damage. subarachnoid hemorrhage is usually caused by the rupture of an intracranial aneurysm or arteriovenous malformation. signs and symptoms of stroke in pregnancy can be confusing. The physician must be aware of these signs to avoid mismanagement of the pregnant stroke patient.- - - - - - - - - - ranking = 0.71428571428571keywords = pregnancy (Clic here for more details about this article) |
5/15. Maternal cortical vein thrombosis and the obstetric anesthesiologist.Maternal cortical vein thrombosis is a potentially fatal complication of pregnancy and the puerperium. patients may present with focal neurologic deficits, seizures, or symptoms indicating increased intracranial pressure. Associated conditions include maternal dehydration and preeclampsia or frank eclampsia. Parturients may require anesthesia for various types of delivery. Safe administration of appropriate anesthesia must take into account the possible presence of a coagulopathy or reduced intracranial compliance. Case presentations, a literature review, possible pathogenetic mechanisms, and specific anesthetic considerations are discussed to enable the obstetric anesthesiologist to develop a rational plan of management.- - - - - - - - - - ranking = 0.14285714285714keywords = pregnancy (Clic here for more details about this article) |
6/15. Unusual manifestations of peripartal cardiac disease.Because peripartal cardiac disease occurs infrequently, its manifestations may be unfamiliar to most physicians. We report two unusual cases of postpartum cardiac disease: one patient presented with cerebral and peripheral arterial embolization, and the second patient developed late eclamptic seizures with subsequent myocardial infarction. Both patients recovered. Nonobstetric physicians should be aware of these pregnancy-associated medical complications to allow prompt diagnosis and aggressive therapy.- - - - - - - - - - ranking = 0.14285714285714keywords = pregnancy (Clic here for more details about this article) |
7/15. Cerebral embolism due to non-bacterial thrombotic endocarditis following pregnancy.A case is reported of cerebral embolism with two very unusual features. Two bilaterally symmetrical haemorrhagic infarcts occurred, due to non-bacterial thrombotic cardiac valvular vegetations precipitated by the puerperium in a previously healthy young woman.- - - - - - - - - - ranking = 0.57142857142857keywords = pregnancy (Clic here for more details about this article) |
8/15. Intracranial venous thrombosis in the first trimester of pregnancy.We describe a fatal case of intracranial venous thrombosis occurring in early pregnancy. Such thrombosis usually occurs in late pregnancy or the puerperium but rarely during the first trimester of pregnancy. Computerized axial tomography suggested massive cerebral venous infarction. Necropsy findings showed not only cerebral venous thrombosis but also extensive pelvic and iliac vein thromboses. The relationship of cerebral venous thrombosis and pregnancy is discussed and the literature reviewed.- - - - - - - - - - ranking = 1.1428571428571keywords = pregnancy (Clic here for more details about this article) |
9/15. Bacterial endocarditis in pregnancy.Bacterial endocarditis in pregnancy is uncommon but serious. A case is presented of subacute bacterial endocarditis with severe aortic and mitral valvular insufficiency and with associated multiple systemic and cerebral emboli. Therapy consisted of cesarean section at 33 weeks' gestation followed by aortic and mitral valve replacement; there was no maternal or fetal mortality. The English literature on infective endocarditis complicating pregnancy is reviewed.- - - - - - - - - - ranking = 0.85714285714286keywords = pregnancy (Clic here for more details about this article) |
10/15. Paroxysmal nocturnal haemoglobinuria in pregnancy: case report.pregnancy in a woman with paroxysmal nocturnal haemoglobinuria was complicated by hepatic venous thrombosis, portal hypertension and haematemesis due to gross oesophageal varices. Labour was induced and a live female infant was born. Dural sinus thrombosis and intracerebral haemorrhage resulted in death on the 46th day post partum. A review of the literature shows that venous thrombosis is common in paroxysmal nocturnal haemoglobinuria.- - - - - - - - - - ranking = 0.57142857142857keywords = pregnancy (Clic here for more details about this article) |
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