1/8. Acute disseminated histoplasmosis complicated with hypercalcaemia.A case of acute progressive disseminated histoplasmosis complicated with hypercalcemia is reported and the literature is reviewed. This and the previously reported cases imply that physicians should have a higher index of suspicion for this infection and the probable underlying diseases resulting from impaired cellular-mediated immunity when encountering patients with hypercalcaemia.- - - - - - - - - - ranking = 1keywords = physician (Clic here for more details about this article) |
2/8. Deep mycoses prevalent in the Igbos of nigeria.During a 3-year period, 6 cases of Africal histoplasmosis, 6 of phycomycosis and 5 of mycetoma were recognized histologically in 0.4 per cent of 4,307 surgical specimens removed from Nigerian Igbos and examined at a central laboratory. Undoubtedly, these cases are but the representatives of the mycological iceberg existing in this part of the world. Our experience suggests that collaboration between physicians, pathologists and mycologists should bring about increased international awareness of the deep mycoses.- - - - - - - - - - ranking = 1keywords = physician (Clic here for more details about this article) |
3/8. meningitis due to histoplasma capsulatum and mycobacterium tuberculosis in a returned traveler with acquired immunodeficiency syndrome.histoplasmosis has rarely been reported in taiwan, and its clinical manifestations may be similar to those of tuberculosis. With increasing international travel, physicians need to be aware of the possibility of this disease when caring for patients with advanced human immunodeficiency virus (hiv) infection who have traveled to endemic areas. A 55-year-old Chinese male from Burma presented with concurrent histoplasmosis and tuberculous meningitis as the initial opportunistic infection of acquired immunodeficiency syndrome. fever, altered mentation, pancytopenia, splenomegaly and marked elevations of serum lactate dehydrogenase (3601 U/L) and ferritin (>10(6) ng/mL) were noted. Despite treatment with amphotericin b and antituberculous therapy, the patient died on the 25th day of hospitalization. This case illustrates the complexity and challenges of management of opportunistic infections in travelers returning from Southeast asia who are in the advanced stage of hiv infection.- - - - - - - - - - ranking = 1keywords = physician (Clic here for more details about this article) |
4/8. fever and high lactate dehydrogenase in hiv-positive patients from the Antilles and Surinam: histoplasmosis?We describe four cases of hiv-positive patients, two from Surinam, one from the Dutch Antilles and one from nigeria, who presented with a febrile illness and a high lactate dehydrogenase plasma level. In all four, the diagnosis of disseminated histoplasmosis was made, in three of them by liver biopsy. Two patients had retinal abnormalities compatible with a systemic fungal infection. Three patients were treated successfully with antifungal agents. One patient died. Between 2000 and 2006, only 14 patients with hiv have been found to have histoplasmosis in the netherlands. Although histoplasmosis is not endemic in the netherlands, physicians are more likely to see cases because of a growing number of hiv -positive immigrants from endemic regions.- - - - - - - - - - ranking = 1keywords = physician (Clic here for more details about this article) |
5/8. AIDS with disseminated histoplasmosis.This report is a description of two ohio cases of acquired immunodeficiency syndrome (AIDS) and disseminated histoplasmosis, with discussion of diagnosis and treatment of this combination. The patient in case 1 developed disseminated histoplasmosis as the first significant symptomatic medical condition of his life. The patient in case 2 presented with severe pharyngitis, but without signs or symptoms specific to the lungs. amphotericin b alone does not eradicate histoplasmosis in an AIDS patient. The best therapy at present is a full course of amphotericin b followed by a lifetime regimen of ketoconazole to prevent relapse. family physicians in the district of columbia, texas, maryland, louisiana, missouri, illinois, arizona, and puerto rico should be particularly vigilant in looking for the combination of these two diseases.- - - - - - - - - - ranking = 1keywords = physician (Clic here for more details about this article) |
6/8. Pulmonary histoplasmosis. A possible risk in people who cut decayed wood.We report three unrelated outbreaks of acute pulmonary histoplasmosis associated with cutting and gathering firewood in minnesota. Clinical symptoms and laboratory findings from nine patients are reported. All recovered without treatment. This report emphasizes that physicians must consider cutting and gathering wood, especially decayed wood, as a potential risk for acute pulmonary histoplasmosis even in areas of the country where histoplasmosis is not considered prevalent.- - - - - - - - - - ranking = 1keywords = physician (Clic here for more details about this article) |
7/8. Isolated nodular cutaneous histoplasmosis. The initial manifestation of recurrent disseminated disease.Cutaneous manifestations of histoplasmosis may be divided into primary and secondary lesions. Primary cutaneous histoplasmosis is rare; to our knowledge, there are only three reported cases in the literature. Secondary cutaneous histoplasmosis develops during the course of disseminated disease. An isolated nodule of the hand was the initially appearing sign of recurrent disseminated disease in our patient. Because of the extreme rarity of primary cutaneous histoplasmosis, cutaneous lesions that are proven to be due to histoplasmosis should alert the physician to the presence of disseminated disease.- - - - - - - - - - ranking = 1keywords = physician (Clic here for more details about this article) |
8/8. Intestinal histoplasmosis in AIDS patients: report of three cases observed in france and review of the literature.We report three cases of colonic histoplasmosis observed in a non-endemic area in patients with AIDS. The patients presented with fever, abdominal pain and an abdominal mass in the right lower quadrant. diagnosis was obtained using Gomori-Crocott staining of endoscopic or surgical biopsies. One patient died without specific treatment and two patients had a complete remission when treated with intravenous amphotericin b but suffered a relapse when given oral itraconazole. Thus, physicians in areas where intestinal histoplasmosis is not endemic should be aware of the condition. diagnosis can easily be obtained using Gomori-Crocott staining of colonoscopic biopsies; this should avoid unnecessary laparotomies and allow specific treatment to be instituted rapidly.- - - - - - - - - - ranking = 1keywords = physician (Clic here for more details about this article) |