Cases reported "Heart Neoplasms"

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11/24. A case of malignant lymphoma simulating acute myocardial infarction.

    A patient with malignant lymphoma suddenly collapsed, and ST segment elevation with complete atrioventricular block was observed on his electrocardiogram during an episode resembling acute myocardial infarction. Cardiac cineangiography revealed posterobasal asynergy of the left ventricle with no significant obstruction in the coronary arterial tree. autopsy revealed diffuse invasion of the myocardium by lymphoma cells. Left ventricular wall motion was preserved even in the area of massive invasion; there was no true necrosis. Myocardial biopsy may be indicated in patients in whom there is a discrepancy between coronary pathoanatomy and wall motion abnormalities.
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12/24. The etiology of tumor plop in a patient with huge right atrial myxoma.

    In a patient with a large atrial myxoma, the phonocardiographic timing of the tumor plop has been correlated with the two-dimensional echocardiographic motion pattern of the cardiac mass. The tumor plop occurred at the time when the mass stopped its diastolic forward motion into the ventricle and made a strong impact on the interventricular septum and right ventricular posterior wall. Occurrence of tumor plop may require a large mass or long enough tumor stalk to allow the impact of the mass on the ventricular wall.
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13/24. Detection of left atrial myxoma with SPECT cardiac imaging.

    A 69-year-old man with a left atrial myxoma underwent a gated cardiac blood pool radionuclide study that failed to visualize the cardiac tumor on either the planar images or on the composite cineangiograms from the anterior and 45 degrees LAO projections. A nongated cardiac SPECT examination, however, easily demonstrated the atrial myxoma in its characteristic location, adjacent to the interatrial septum. SPECT dramatically improved the image contrast; provided views in transaxial, coronal, and sagittal planes; and allowed direct comparison with computed tomography. Gated cardiac SPECT may be expected to provide a more accurate analysis of the complex motion and attachment site of these intracardiac tumors, as well as a more accurate tumor volume analysis.
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14/24. Abnormal diastolic movement of the interventricular septum caused by a prolapsing right atrial myxoma.

    A 40 year old woman with cough and exertional dyspnoea was found to have a large right atrial myxoma by M mode and cross sectional echocardiography. prolapse of the tumour into the right ventricle occurred during diastole with sufficient force to cause mechanical distortion of the interventricular septum. Septal motion became normal after surgical resection of the myxoma.
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15/24. Two-dimensional echocardiographic findings in a case of massive cardiac involvement by malignant lymphoma.

    In a patient affected by malignant mediastinal lymphoma a severe congestive heart failure and the ECG pattern suggested a heart involvement. Two-dimensional echocardiography (2DE) documented the presence of abnormalities suggestive of infiltration: in particular, enormous thickening of the left ventricle, nearly absent wall motion, and "patchy" appearance of the myocardium were seen. Necropsy findings confirmed the presence of a massive lymphomatous infiltration of the heart. 2DE, by its ability to detect abnormalities consistent with heart infiltration, should provide a useful contribution in the staging of lymphomas.
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16/24. Ultrasonic demonstration of right ventricular myxoma.

    A case of right ventricular myxoma masquerading as infundibular pulmonic stenosis with right-sided heart failure is presented. The unsuspected tumor was diagnosed with two-dimensional multicrystal real time scanning and single element echocardiography. Direct visualization of the tumor anatomy and its spatial relationships on cross-sectional images facilitates the diagnosis. On the other hand, the more accurate motion analysis form the time-motion display of the echo data yields additional functional information. Thus the two techniques are complementary to establish a diagnosis in those disorders where anatomy and function overlap. Ultrasonic examination yields a practical solution to the problem of screening patients to detect intracardiac tumors. This painless, noninvasive examination should be included in the analysis of every patient with cardiac symptoms.
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17/24. Left atrial myxoma: phonocardiographic, echocardiographic, and micromanometric hemodynamic correlations.

    We used simultaneous echocardiography, phonocardiography, and high-fidelity micromanometry to investigate the impact of the movement of a large pedunculated left atrial myxoma on hemodynamics. The case we have described shows that (1) the early diastolic sound (tumor plop) coincided with maximal excursion of the tumor in the left ventricular inflow tract, (2) tumor movements during mid to late diastole corresponded to low-frequency oscillations in left ventricular pressure, (3) tumor expulsion from the left ventricle into the left atrium was initiated during "isovolumic" contraction but continued into the early ejection phase, (4) mitral valve closure was abnormally delayed until after the onset of aortic ejection, and (5) systolic ejection was initiated before coaptation of the mitral valve leaflets. These findings support the theory that tumor motion contributes to both systolic and diastolic vibrations of the entire cardiohemic system.
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18/24. Right ventricular mural thrombus caused by myocardial infarction diagnosed by computed tomography.

    Thrombi of the left ventricle are common sequelae to acute anterior myocardial infarctions that involve the apex of the heart and produce akinetic or dyskinetic wall thickening patterns. While infarctions of the right ventricle are being increasingly recognized in the setting of inferior myocardial infarcts, little data on in vivo clot formation in the right ventricle of the heart are available in these patients. In the current study we were able to demonstrate a right ventricular mural thrombus using gated computed tomography of the heart. Although an abnormality in the right ventricle extending from the septal margin of the ventricle into the outflow tract could be identified with standard blood pool computed tomographic images and from cross sectional echocardiograms, only with cardiac gating could the relationship between the mass (thrombus) and the noncontractile section of the right ventricular myocardium be clearly identified. We conclude that cardiac gating may help in the evaluation of cardiac masses, and in particular cardiac thrombi. This will be particular valuable in the setting of recent or remote infarction, as the relationship between wall-motion abnormalities and thrombus formation has been well documented.
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19/24. Correlation of phono- and apexcardiographic findings with tumor motion in left atrial myxoma.

    We have analyzed the genesis of physical signs in a case of prolapsing left atrial myxoma by simultaneous phono-, apex- and M-mode echocardiography. Our findings confirm a direct relationship of tumor movements with notching in the upstroke of the apexcardiogram and with the protodiastolic "tumor plop."
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20/24. "Pseudo-tumor" of the right ventricular outflow tract and congenital pulmonary valve regurgitation: a case report.

    The M-mode and 2-D echocardiographic features of an unusual case of a "pseudo-tumor" of the right ventricular outflow tract are reported. The unique pathologic findings of the pulmonary valve with congenital fenestrations and the clinical implications of this "pseudo-tumor" are discussed. Whenever calcification is noted at fluoroscopy to exist in a region or structure being evaluated by echocardiography, caution must be taken to avoid overestimating the size. Indistinct, dense reflectances without specific motion or appearance of a mass further helps to distinguish the reflectances from an actual structure of significance. Furthermore, all clinical, angiographic, and echocardiographic information must be interpreted together when either the angiogram or the echocardiogram is confusing and potentially misleading.
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