1/22. fever of unknown origin due to inflammatory pseudotumour of lymph nodes.The clinical features of inflammatory pseudotumour of lymph nodes, a distinct non-malignant histopathological entity firstly described in 1988, are summarized based upon a detailed analysis of 4 personal cases and 47 cases reported in the literature. The mean age of the patients is 38 years (range 8 to 82 years) and there is no gender predilection. One third present with asymptomatic lymphadenopathy and 47% present with fever, nearly all meeting the criteria of fever of unknown origin. Abdominal complaints are occasionally present. Intermittence of symptoms is common. Hepatosplenomegaly is unusual. All lymph node areas may be involved but abnormalities are mostly confined to one or two anatomic regions. No extranodal involvement has been reported although inflammatory pseudotumour may occur in several organs with similar morphological features and identical signs of inflammations. Routine blood tests are normal except for signs of inflammation. The lesions are gallium-avid. diagnosis is based upon typical histopathological features. The prognosis is favorable and surgical resection frequently leads to cure. Spontaneous resolution of symptoms has been reported and nonsteroidal anti-inflammatory drugs may suppress the clinical manifestations.- - - - - - - - - - ranking = 1keywords = inflammation (Clic here for more details about this article) |
2/22. Endoscopic preoperative colonic tattooing: a clinical and surgical complication.Endoscopic colonic tattooing is the simplest and most economic technique for identifying small lesions or polypectomy sites during open and laparoscopic surgery. Moreover, it is useful for the endoscopic follow-up of polypectomy sites. india ink is the agent of choice because of its long-lasting stain and the low risk of adverse reaction and toxicity. Very few cases of complications have been reported. We report here the case of a patient in whom colonic tattooing in preparation for surgical resection was followed by clinical complications such as fever and abdominal pain. An abscess-type inflamed pseudotumor was found at laparotomy. Histological examination revealed chronic granulomatous inflammation.- - - - - - - - - - ranking = 0.5keywords = inflammation (Clic here for more details about this article) |
3/22. Sclerosing inflammatory pseudotumor of the eye.We report the clinical course and pathologic findings in a case of intraocular sclerosing inflammatory pseudotumor in a 21-year-old man. The patient initially had a unilateral right interstitial keratitis, scleritis, uveitis, ciliary body mass, and retinal detachment. Scleral and vitreous biopsy specimens revealed an inflammatory process. The eye was eventually enucleated despite therapy with high doses of prednisone and ciprofloxacin hydrochloride. Histologic examination of the globe showed nongranulomatous, acute (neutrophils) and chronic (lymphocytes and histiocytes) inflammation with proliferation of fibrous tissue within the vitreous cavity, uvea, sclera, and contiguous orbital fibroadipose tissue. The contralateral eye later developed a similar mass that resolved following aggressive and prolonged immunosuppressive therapy with retention of 20/16 visual acuity.- - - - - - - - - - ranking = 0.5keywords = inflammation (Clic here for more details about this article) |
4/22. Intracranial plasma cell granuloma.plasma cell granulomas (PCGs) are benign, inflammatory masses of unknown etiology composed of polyclonal mature plasma and lymphoid cells. The lung is their most common location, and occurrence within the cranial cavity is extremely rare. We report the case of an 11-year-old girl who presented with seizures and was diagnosed as having a dural-based right frontal tumor that extended toward the sagittal sinus and the falx. The lesion was totally excised, together with the abnormal dura. A limited cortical excision was also performed using electrocorticographic guidance. Histopathologic diagnosis of intracranial plasma cell granuloma was reached after extensive immunohistochemical tests and electron microscopy. This is the third case of PCG with description of changes in the neighboring cerebral tissue. Although PCGs are well-circumscribed lesions, lymphoplasmocytic inflammation, neuronal loss, and reactive gliosis occur within the adjacent cortex. Disturbed cortical lamination, as we have observed, appears to be a histological finding that has not been described previously.- - - - - - - - - - ranking = 0.5keywords = inflammation (Clic here for more details about this article) |
5/22. Inflammatory pseudotumour involving the skull base and cervical spine.Inflammatory pseudotumour (IPT) is an idiopathic condition characterized by sclerosing inflammation, which mimics a neoplastic process. IPT involving the skull base and cervical spine is distinctly rare and usually indistinguishable from aggressive neoplasms or infection. We report a case of IPT involving the skull base and cervical spine. Initially the patient complained of headache and hearing loss without other neurological dysfunction. Two cycles of oral systemic steroid therapy resulted in only partial responses. Low dose radiotherapy was followed by quadriparesis as the lesion infiltrated into the cervical vertebral bodies. Subsequently a second course of radiation was administered to the whole cervical spine. Marked improvement was observed clinically and radiologically; however, the patient gradually deteriorated and died of sepsis. Given the aggressive nature of disease and the complications related to the long-term treatment, we suggest that a more aggressive therapeutic approach is suitable in extensive IPT of the skull base.- - - - - - - - - - ranking = 0.5keywords = inflammation (Clic here for more details about this article) |
6/22. Injuries from palm tree thorn simulating tumoral or pseudotumoral bone lesions.Three cases of bone changes caused by foreign bodies that appeared to be tumoral lesions or pseudotumors, were observed in young male patients who presented with pain, localized inflammation, and radiographic and bone scan findings suggestive of tumoral or pseudotumoral lesions. Accurate diagnosis was made at surgery when the foreign body was retrieved. Following removal of the foreign body, postoperative recovery was satisfactory. The common causative agent in all these cases was a palm tree thorn.- - - - - - - - - - ranking = 0.5keywords = inflammation (Clic here for more details about this article) |
7/22. Chronic idiopathic inflammation of the retropharyngeal space presenting with sequential abducens palsies.We describe a patient who presented with sequential, bilateral abducens palsies associated with a mass of the nasopharynx. biopsy of the mass showed chronic non-specific inflammation and fibrosis. The diagnosis of idiopathic inflammatory pseudotumor was arrived at by exclusion of other known causes of inflammation of the retropharyngeal space. magnetic resonance imaging suggested that injury to the sixth cranial nerves probably occurred as they traversed the dura and subarachnoid space overlying the clivus.- - - - - - - - - - ranking = 3keywords = inflammation (Clic here for more details about this article) |
8/22. Use of advanced imaging modalities for the differential diagnosis of pathoses mimicking temporomandibular disorders.The medical records of 3 patients who visited our hospital with preauricular pain and limited jaw movement were retrospectively reviewed. All were clinically evaluated, diagnosed through the use of conventional radiographs, and initially treated as having temporomandibular disorders (TMD). However, their symptoms did not improve and even increased or facial swelling occurred, so advanced imaging modalities were used to make a differential diagnosis. The final diagnoses of the patients were cellulitis, an inflammatory pseudotumor, and pigmented villonodular synovitis. In addition to these 3 patients, 50 others who were initially misdiagnosed during a clinical examination as having TMD on conventional radiographs were reviewed in the English-language literature. When diagnosing patients with TMD symptoms, we must consider the possibility of unusual causes, including tumors and infections or inflammations. Furthermore, in addition to usual TMD treatment procedures, an advanced radiologic examination should be performed to aid in the differential diagnosis of all patients with unceasing pain and mouth-opening limitation.- - - - - - - - - - ranking = 0.5keywords = inflammation (Clic here for more details about this article) |
9/22. Pseudotumour orbitae as the initial manifestation in Wegener's granulomatosis in a 7-year-old girl.Wegener's granulomatosis (WG) is a systemic granulomatous vasculitis that typically affects the upper airways, lungs and kidneys. This form of vasculitis is extremely rare in children, the most common form of paediatric systemic vasculitis being Henoch-Schonlein purpura (HSP). Children with systemic vasculitis look ill and have multiple constitutional complaints, often with prolonged fever. As in adults, WG in children is a multisystem disease. There are no precise statistical data concerning ocular involvement in Wegener's granulomatosis in children. Ocular disease occurs in 50%-60% adult patients with WG and may be an extension of the sinus inflammation or an orbital pseudotumour independent of the sinus disease (15%-50%); sometimes it presents as an ocular myositis. The most common presenting sign of orbital disease is ptosis and anterior displacement of the eye, pain, blurred vision, eyelid swelling and reduction of eye motility. Here we present the case of a 7-year-old girl with WG whose initial manifestation was pseudotumour orbitae. This patient was negative for an initial c-ANCA test. biopsy specimens obtained from the lacrimal gland and kidney demonstrated granulomatous vasculitis. Treatment with glucocorticoids and cyclophosphamide led to complete, long-lasting remission.- - - - - - - - - - ranking = 0.5keywords = inflammation (Clic here for more details about this article) |
10/22. Posttraumatic spindle cell nodule of the buccal mucosa. Report of a case.A benign posttraumatic spindle cell proliferation arising at a site of laceration in the buccal mucosa of a 19-year old man is described. This lesion, which histologically mimicked a leiomyosarcoma, appears to represent a reactive process similar to that described as postoperative spindle cell nodules of the genitourinary tract. Reexcision of the area 1 month after biopsy revealed only scar formation and mild chronic inflammation. Recognition of this type of benign spindle cell proliferation at traumatized sites in the oral cavity is important if misdiagnosis and subsequent aggressive therapy is to be avoided.- - - - - - - - - - ranking = 0.5keywords = inflammation (Clic here for more details about this article) |
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