1/54. Bone giant cell tumour in neuropathological practice. A fifty year overview.We report a case of a 29-year-old female patient who suffered from visual disturbance, resulting from a lesion in the sphenoid bone which, histologically, proved to be a giant cell tumour. Reviewing our laboratory practice over a 50 year period, only 7 cases of true giant cell tumour were found and they were in two major locations, i.e. the skull and vertebrae. These few cases led us to focus on the problem raised by the lack of histological patterns of malignancy. In agreement with Mazabraud's theory, it seems that a vertebral location is associated with a good prognosis and that gene mapping of chromosome 17 in relation to p53 mutations could be a valuable tool in the diagnosis of potential malignant behaviour.- - - - - - - - - - ranking = 1keywords = cell tumour (Clic here for more details about this article) |
2/54. Assessment of vascularized fibular graft one year after reconstruction of the wrist after excision of a giant-cell tumour.We report a patient in whom the distal radius was resected for a giant cell tumour and the bone defect was replaced using a vascularized proximal fibular graft. The graft was viable and hypertrophied and normal callus formed on the distal radius. Due to chronic instability of the wrist the patient underwent revision arthrodesis 1 year after resection. Microscopic studies of the epishyseal region of the fibula showed wide necrosis of the graft with active creeping substitution. Despite the good technical result of the vascularized fibular graft, the vascularization was incomplete in the proximal epiphysis. We discuss possible reasons for this.- - - - - - - - - - ranking = 0.83333333333333keywords = cell tumour (Clic here for more details about this article) |
3/54. Synchronous multicentric giant cell tumour: a case report with review of literature.Synchronous multicentric giant cell tumour (MGCT) is a rare occurrence. We report a young woman who presented with a synchronous skull and lower shaft femur giant cell tumour, who had previously received radiotherapy to both the sites, it being deemed inoperable at initial assessment.- - - - - - - - - - ranking = 1keywords = cell tumour (Clic here for more details about this article) |
4/54. Giant-cell tumour involving the cranial vault: imaging and treatment.A giant-cell tumour involving the cranial vault was diagnosed in a 37-year-old man who presented with a large swelling at the vertex. The role of imaging in the diagnosis and treatment of this tumour is described. On CT and MRI the appearances were nonspecific and the diagnosis was established by histological examination after removal of the tumour. A preoperative angiogram showed a tumour blush and before surgery, embolisation was performed via the percutaneous and transarterial routes.- - - - - - - - - - ranking = 0.83333333333333keywords = cell tumour (Clic here for more details about this article) |
5/54. Giant cell tumour of the hyoid--first reported case.Giant cell tumours of bone are most commonly found in the epiphyses of weight-bearing long bones. They are rarely found in the head and neck and only 17 cases involving the laryngeal framework have been reported. To date, there have been no reports of a giant cell tumour arising from the hyoid bone. We present such a case which presented as a lump overlying the greater cornu of the hyoid, review the literature and discuss the management of this locally aggressive tumour.- - - - - - - - - - ranking = 1keywords = cell tumour (Clic here for more details about this article) |
6/54. Distal fibular giant cell tumour.A patient who reported with a slowly growing swelling ovr thee lateral aspect of the left ankle, was investigated and diagnosed to have a giant cell tumour which was confirmed on FNAC. The tumour was managed with excision biopsy and reconstruction. The case is being reported for its rare site of occurrence.- - - - - - - - - - ranking = 0.83333333333333keywords = cell tumour (Clic here for more details about this article) |
7/54. Giant cell tumour of the temporal bone: case report and review of the literature.This paper presents an expansile lesion of the temporal bone, in a 14-year-old boy, that was initially diagnosed as intra-osseous meningioma from CT appearance. At histopathology a final diagnosis of giant cell tumour was made. A brief review of the literature is presented for this rare case.- - - - - - - - - - ranking = 0.83333333333333keywords = cell tumour (Clic here for more details about this article) |
8/54. Two rare lumbar tumours with unusual MRI characteristics.We present two rare lumbar lesions with similar MRI features: high signal on T1-weighted and proton density images and low signal on T2-weighted images; a melanotic schwannoma, and a giant-cell tumour-like lesion. Melanin in the first case and haemosiderin and metahaemoglobin in the second were responsible for the MRI characteristics.- - - - - - - - - - ranking = 0.16666666666667keywords = cell tumour (Clic here for more details about this article) |
9/54. Giant cell tumour of talar body.Giant cell tumour (osteoclastoma) of talar bone is a rare entity and is seen more commonly in the third decade of life. We report this disease entity in a 17-years-old girl. The patient presented with painful swelling of the left ankle with an osteolytic lesion in the talus on conventional radiographs. Intralesional curettage and autologous bone grafting was performed following which patient's pain and swelling disappeared. Complete range of movement at the ankle joint was regained with minimal restriction at the subtalar joint. There is no evidence of relapse at six months follow up.- - - - - - - - - - ranking = 0.83333333333333keywords = cell tumour (Clic here for more details about this article) |
10/54. Primary malignant giant cell tumour of bone--a study of two cases with short review.Primary malignant giant cell tumour of bone is extremely rare. It is distinctly separate from benign metastasising giant cell tumour of bone and secondary malignant giant cell tumour which occurs in response to radiotherapy and repeated curettage of benign giant cell tumor. The tumor has high mortality rate. It usually affects lower end of femur and upper end of tibia. Two usually affects lower end of femur and upper end of tibia. Two cases, on involving upper end of tibia and other in vertebra are discussed. Extreme paucity of literature prompted to publish this article. A short review of radiological appearance, histopathological findings and treatment modalities is highlighted.- - - - - - - - - - ranking = 1.1666666666667keywords = cell tumour (Clic here for more details about this article) |
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