1/9. Nodular fasciitis presenting as a parotid tumour after face lifting.Nodular fasciitis, a benign, pseudosarcomatous proliferative lesion of the soft tissue, is frequently misinterpreted as a sarcoma, both clinically and microscopically. Lesions associated with the parotid gland have been very rarely reported. We report a case of nodular fasciitis mimicking a parotid tumour after a facelift. We performed histological and immunohistochemical study and CT scan for it is difficult to make a differential diagnosis. We confirmed the final diagnosis as intraparotid nodular fasciitis. Superficial parotidectomy was performed because of initial pathological misdiagnosis reported as a dermatofibroma. The subsequent diagnosis was confirmed to be nodular fasciitis on the basis of immunohistochemical study. There was no recurrence after follow-up to 18 months. Proper diagnosis of nodular fasciitis in the parotid region and early recognition of its benign nature are necessary to differentiate it from other various benign and malignant tumours of the parotid gland.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
2/9. Parotid nodular fasciitis in a mobile phone user.We describe the first case of nodular fasciitis affecting the deep lobe of the parotid gland in a 39-year-old male telephone engineer and its possible association with the high usage of mobile phones.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
3/9. Nodular fasciitis of parotid region: a pitfall in the diagnosis of pleomorphic adenomas on fine-needle aspiration cytology.Fine-needle aspiration cytology (FNAC) is routinely employed for the preoperative diagnosis of salivary gland lesions. Although most cases show morphologic features characteristic of specific entities, some lesions can be diagnostically challenging. We report two parotid aspirates, initially diagnosed as pleomorphic adenoma on FNA. The patients, a 33-yr-old white man, and a 24-yr-old white woman, presented with indurated lesions arising in the parotid gland region. The aspirates from both patients were markedly hypercellular. Smears showed a mixture of spindle cells with a well-demarcated cytoplasm showing occasional long cytoplasmic process; and cells with abundant cytoplasm with round to oval eccentric nuclei, giving the impression of plasmacytoid cells of pleomorphic adenoma. The nuclear chromatin was evenly distributed and finely granular with one or two occasional small nucleoli. Intermingled with the tumor cells were scattered neutrophils, eosinophils, and macrophages. Aggregates of spindle cells were also seen embedded in a mucoid background with occasional small tufts of a fibrillar mucoid stroma. These fibrillar tufts were magenta red in the Diff-Quik stain, giving the impression of matrix of pleomorphic adenoma. Both cases were later diagnosed on histologic examination as nodular fasciitis. Nodular fasciitis should be considered in the differential diagnosis of a mass arising in association with the parotid gland.- - - - - - - - - - ranking = 1.5keywords = gland (Clic here for more details about this article) |
4/9. Nodular fasciitis in the orofacial region.Nodular fasciitis (NF) is a benign, reactive proliferation of fibroblasts in subcutaneous tissues which commonly occurs in the deep fascia. It can only be diagnosed by histopathological examination of a biopsy. A total of 23 orofacial NF patients was analysed, including those reported in the English language literature and six new patients from the files of this hospital. All patients were treated between 1994 and 2005. The reported lesions were located in cheek masseter muscle, parotid gland, upper neck, upper gingiva and body of mandibular. The clinical and histological features and differential diagnoses are discussed. All lesions were removed under general or local anaesthesia and no recurrence of the lesions was found.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
5/9. Papillary carcinoma of thyroid with exuberant nodular fasciitis-like stroma. Report of three cases.Three examples of an unusual morphologic variant of papillary thyroid carcinoma (PTC) are reported. The presence of a prominent stromal component resulted in low-power microscopic appearances resembling fibroadenoma, phyllodes tumor, or fibrocystic disease of the breast in two cases. The carcinomatous component grew in the form of anastomosing narrow tubules, clustered glands, solid sheets with or without squamous differentiation, and/or papillae, and exhibited the typical nuclear features of PTC. The abundant stroma had a nodular fasciitis-like quality and was composed of short fascicles of spindle cells separated by varying amounts of mucoid matrix, collagen, and extravasated red blood cells; this was interpreted as an exuberant mesenchymal reaction to the carcinoma. The importance of recognizing this variant of PTC is that, when one encounters a fibroproliferative lesion of the thyroid, a diligent search should be made for papillary carcinoma. This variant also must be distinguished from the vastly more aggressive papillary carcinomas with anaplastic transformation and the so-called carcinosarcomas.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
6/9. Intraparotid nodular fasciitis.We describe two cases of nodular fasciitis arising within the parotid glands of two patients, a 42-year-old man and a 2 1/2-year-old boy. The clinicopathologic, immunohistochemical, and ultrastructural features of this lesion and its differential diagnosis are discussed.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
7/9. Proliferative myositis of the masseter muscle. A case report and a review of the literature.A case of proliferative myositis of the masseter muscle in a 62-year-old woman is presented and pertinent literature is reviewed. This benign pseudosarcomatous proliferative lesion has not been previously reported in any of the muscles of mastication. Clinically the patient presented with pain and difficulty in opening of the mouth. On initial examination, a malignant salivary gland tumor was suspected. The proliferative myositis exhibits a disturbing microscopic appearance characterized by the presence of numerous hyperchromatic fibroblasts and oval or spindle-shaped giant cells which resemble malignant rhabdomyoblasts. These lesions have been often misdiagnosed as rhabdomyosarcoma and other types of sarcomas. awareness of the microscopic characteristics of proliferative myositis and the possibility of its occurrence in the perioral soft tissues is important in avoiding misdiagnosis of this benign condition.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
8/9. Nodular fasciitis of the parotid gland. Report of a case with presentation in an unusual location and cytologic differential diagnosis.The histomorphology of nodular fasciitis (NF), a benign proliferation of myofibroblasts, is well described in the surgical pathology literature. The cytomorphology, however, has been reported infrequently. Cytologic interpretation of this pseudosarcomatous lesion is subject to the same pitfalls so frequently reported for histologic material. NF arises most commonly in the extremities or trunk; occurrence in the parotid gland is relatively uncommon. We describe a case of NF arising in association with the parotid gland; review the clinical, cytologic, histologic and immunohistochemical features of NF; and offer a differential diagnosis, based on cytologic features, of other benign and malignant lesions likely to be encountered at this location.- - - - - - - - - - ranking = 3keywords = gland (Clic here for more details about this article) |
9/9. Necrotizing surgical infection and necrotizing fasciitis in obstetric and gynecologic patients.Necrotizing fasciitis (NF) is a rapidly progressive disease characterized by extensive necrosis of the skin, fascia, and subcutaneous tissue, with sparing of the underlying muscle. diabetes mellitus, Bartholin's gland abscess, and recent surgical procedures (including episiotomy) are factors often found in obstetric and gynecologic patients. mortality in this group of patients is higher than in the general surgical population. death is usually due to overwhelming sepsis, renal and respiratory failure, and multiple organ failure. The infections are usually polymicrobial, with alpha-hemolytic streptococci, gram-negative coliforms, and anaerobic bacteria. Lower survival has been reported in large series when the groin is involved or when the general nutritional state is poor. From October 1988 to August 1990, we treated five patients with necrotizing fasciitis. Certain important characteristics of such patients have not been discussed in the obstetric and gynecologic literature. nutritional status, with special emphasis on total protein, albumin, and the effects of alcoholism, has a significant impact on mortality. nutritional support of these patients may improve survival. To limit the impact of secondary infections, surgical approaches should be modified by the anatomic location of the initial lesions. More frequent debriding in the operating room and early fecal diversion are recommended.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |