11/130. cowpox infection: not yet consigned to history.Two patients presented with hard black eschars covering granulating ulcers. The ulcers healed within 6 weeks to leave small scars. The diagnosis of cowpox was confirmed by serology in both cases and in addition by polymerase chain reaction in the first. The source of infection was likely to be a rodent in the first case whilst the second was more typical in being transmitted by a cat.- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
12/130. Recalcitrant molluscum contagiosum in an hiv-afflicted male treated successfully with topical imiquimod.molluscum contagiosum is a common cutaneous infection complicating the course of patients afflicted with acquired immunodeficiency syndrome. We describe a human immunodeficiency virus-positive patient with a disfiguring molluscum contagiosum infection of the face. Conventional cytodestructive therapies failed in this patient, but imiquimod 5% cream, an immunomodulator, clinically cleared his cutaneous disease.- - - - - - - - - - ranking = 0.4keywords = infection (Clic here for more details about this article) |
13/130. Refractory facial cellulitis following cosmetic rhinoplasty after cord-blood stem cell transplantation.We report a case of a 38-year-old female patient who developed facial cellulitis after cord-blood stem cell transplantation (CBT). The cellulitis was refractory to treatment with antibiotics and antifungal agents. Because facial cellulitis is rare after transplantation, its mechanism could not be determined exactly. On day 40 after CBT, a nurse with expertise in cosmetic surgery attended our rounds and correctly assumed that the patient had received cosmetic rhinoplasty. Although conventional x-rays of the head were normal, a computed tomographic (CT) scan of the brain disclosed the presence of a foreign body over the nasal dorsum. As a result, the patient's symptoms were diagnosed as facial cellulitis associated with foreign material that had been implanted at the time of cosmetic surgery. At a pretransplantation interview, the patient did not mention her history of rhinoplasty. Even after she was shown the head CT scans that revealed the presence of nasal implants, she denied that she had received rhinoplasty before CBT. Unless we realize that patients may have received cosmetic surgery before transplantation, it is difficult to make a diagnosis of infection associated with foreign implants. To our knowledge this is the first report after transplantation of infection associated with cosmetic surgery. Such infections should be included on the list of complications after bone marrow transplantation.- - - - - - - - - - ranking = 0.6keywords = infection (Clic here for more details about this article) |
14/130. chediak-higashi syndrome.A case of chediak-higashi syndrome is reported in a four-year-old boy who presented with recurrent chest infection, partial albinism, hyperpigmentation of the extremities and presence of giant granules in leucocytes and melanocytes in the skin. Parental consanguinity was present. Though uncommon, hyperpigmentation of sun exposed areas may be the initial symptom in chediak-higashi syndrome.- - - - - - - - - - ranking = 0.2keywords = infection (Clic here for more details about this article) |
15/130. Persistent annular erythema of infancy associated with intestinal Candida colonization.We report a case of persistent annular erythema of infancy in a 4-month-old boy. Physical and laboratory parameters showed no sign of internal disease or specific infection except a massive candida albicans colonization (> 103 organisms/mm3) of the lower gastrointestinal tract. Oral treatment with amphotericin b for 2 weeks resulted in a complete remission of the skin lesions indicating Candida colonization as a trigger.- - - - - - - - - - ranking = 0.2keywords = infection (Clic here for more details about this article) |
16/130. eczema herpeticum during treatment of atopic dermatitis with 0.1% tacrolimus ointment.Recent evidence suggests that 0.1% tacrolimus ointment is an effective treatment of atopic dermatitis. tacrolimus is an immunosuppressive agent that interferes with cell-mediated immunity. We have observed 2 cases of eczema herpeticum among 36 patients with atopic dermatitis treated with a topical preparation containing 0.1% tacrolimus. A 29-year-old male patient developed generalized herpetic lesions on his face on the 4th day of treatment. His SCORAD was then 73, and the tacrolimus blood level was 7.5 ng/ml. A 23-year-old woman developed disseminated herpetic lesions on her neck, face, shoulders and legs during the 9th week of treatment. Her SCORAD was then 41, tacrolimus blood levels were <3 ng/ml 2 weeks before the infection. herpes simplex virus type 1 antigens were identified in several lesions by direct immunofluorescence in both patients. Neither patient recalled previous episodes of cold sores. The lesions resolved quickly under intravenous acyclovir treatment but resulted in important facial scarring in the male patient. CONCLUSIONS: eczema herpeticum is a well-known complication of atopic dermatitis. Available data do not allow to link topical tacrolimus with an increased risk for eczema herpeticum, but they are insufficient to exclude an association. Future studies and careful documentation of cases are needed in order to better characterize patients at risk.- - - - - - - - - - ranking = 0.2keywords = infection (Clic here for more details about this article) |
17/130. tinea faciei due to microsporum canis abscess formation.Superficial dermatophyte infections are common in children; however, complications are encountered rarely. We describe a child with tinea faciei caused by microsporum canis, who subsequently developed an abscess. Complete resolution occurred after treatment with oral terbinafine.- - - - - - - - - - ranking = 0.2keywords = infection (Clic here for more details about this article) |
18/130. Successful treatment of molluscum contagiosum with topical imiquimod in a severely immunocompromised hiv-positive patient.molluscum contagiosum is a common viral infection in the immuno-compromised hiv-positive patient where it is often severe and affecting the face and neck. It is frequently resistant to conventional, locally destructive therapies. Anecdotal evidence suggests that the immunomodulatory drug imiquimod might be a valid therapeutic option in this group of patients. We report the case of a severely immunocompromised hiv-positive patient with resistant facial molluscum contagiosum lesions that responded to topical imiquimod. The response to therapy and the possible implications for pathogenesis are discussed.- - - - - - - - - - ranking = 0.2keywords = infection (Clic here for more details about this article) |
19/130. Oral manifestation of sporotrichosis in AIDS patients.A wide spectrum of oral lesions has been associated with human immunodeficiency viral infection (hiv), or AIDS. This report describes the case of an hiv-infected patient who developed a case of disseminated sporotrichosis whose first clinical sign was the presence of orofacial lesions. A histopathological study of this patient's biopsy specimens taken from the oropharyngeal lesions revealed a number of rounded and/or oval free-spore forms of sporothrix schenkii, the identification of which was corroborated by culturing skin lesion exudate on Sabouraud's glucose agar. To the best of our knowledge to date, this is the first time a case of the oral manifestation of sporotrichosis in association with hiv infection has been described in the dental literature.- - - - - - - - - - ranking = 0.4keywords = infection (Clic here for more details about this article) |
20/130. Vesiculopustular eruptions in down syndrome neonates with myeloproliferative disorders.BACKGROUND: Infants with down syndrome are at increased risk for hematologic abnormalities, including leukemoid reaction, transient myeloproliferative disorder, and congenital leukemia. The differential diagnosis of a vesiculopustular eruption in an infant with down syndrome and these hematologic abnormalities is broad and includes benign, self-limited disorders as well as life-threatening infections. observation: We describe 3 newborns with down syndrome and vesiculopustular eruptions associated with myeloproliferative disorders during the neonatal period. These lesions differ from other neonatal vesicular eruptions in that they have a unique distribution, display pathergy, and contain immature hematopoietic cells similar to circulating blast cells. Resolution occurs without treatment as the hematologic disorder subsides. CONCLUSIONS: Infants with down syndrome and hematologic abnormalities may have a cutaneous eruption that has characteristic clinical and histopathologic findings. It is possible that this eruption has been unrecognized in the past because of its self-limited course. Whether this eruption is a prognostic factor for the subsequent development of leukemia is uncertain.- - - - - - - - - - ranking = 0.2keywords = infection (Clic here for more details about this article) |
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