11/82. brain involvement in Dengue fever.During the 1994-1995 outbreak of dengue fever in new caledonia (1079 cases), two cases of encephalopathy were seen. Both patients suffered transient clinical (drowsiness, confusion) and electroencephalographic disturbances from which they fully recovered. Although this condition has been described in dengue infection a number of different pathological mechanisms are probably implicated.- - - - - - - - - - ranking = 1keywords = fever (Clic here for more details about this article) |
12/82. First isolation of dengue 3 in brazil from an imported case.The authors report the isolation of dengue 3 virus for the first time in brazil. The patient, resident in Limeira-SP, traveled to nicaragua on May 16th, 1998, where he stayed for two months. Starting on August 14 th he had fever, headache, myalgia, arthralgia, retro-orbital pain and diarrhea. He returned to brazil on August 16th and was hospitalized in the next day. The patient had full recovery and was discharged on August 20th. The virus was isolated in C6/36 cell culture inoculated with serum collected on the 6th day after the onset of the symptoms. The serotype 3 was identified by indirect immunofluorescence assays performed with type-specific monoclonal antibodies. This serotype was further confirmed by polymerase chain reaction analysis. The introduction of a new dengue serotype in a susceptible population is a real threat for the occurrence of severe forms of the disease. The isolation and identification of dengue virus are important in order to monitoring the serotypes circulating in brazil and to take the measures necessary to prevent and control an epidemic.- - - - - - - - - - ranking = 0.2keywords = fever (Clic here for more details about this article) |
13/82. Dengue fever: a harmful disease in patients with thrombocytopenia?We describe 2 patients with autoimmune thrombocytopenic disease who developed classic dengue fever associated with serious bleeding and extremely low platelet counts (1000 cells/mm(3) and 3000 cells/mm(3), respectively). Such patients should be properly advised as to the possibility that common dengue fever may substantially enhance their risk for hemorrhagic complications.- - - - - - - - - - ranking = 1.2keywords = fever (Clic here for more details about this article) |
14/82. dengue virus type 3 in Rio de Janeiro, brazil.dengue virus type 3 was isolated for the first time in the country as an indigenous case from a 40 year-old woman presenting signs and symptoms of a classical dengue fever in the municipality of Nova Iguacu, State of Rio de Janeiro. This serotype has been associated with dengue haemorrhagic epidemics and the information could be used to implement appropriate prevention and control measures. Virological surveillance was essential in order to detected this new serotype.- - - - - - - - - - ranking = 0.2keywords = fever (Clic here for more details about this article) |
15/82. Dengue fever in the czech republic.BACKGROUND: Dengue fever has become, in Western europe, the second most frequently imported disease after viral hepatitis a. OBJECTIVES: Dengue fever was diagnosed at the Department of Infectious disease, University Hospital in Brno, so the authors decided to make local physicians aware of the possibility of the disease being contracted by Czech travelers. methods: The first two cases of dengue fever, with the patients hospitalized at the Department of Infectious disease, University Hospital in Brno, czech republic, are described. RESULTS: A young couple contracted this infection in a region usually visited by tourists in thailand. The disease broke out 12 hours after their return home. The clinical and laboratory pictures of the disease and the kinetics of serological responses are described in detail. CONCLUSION: The chief diagnostic clue with this disease, beside a visit to a high-risk area, can be considered a sudden onset of fever accompanied by marked fatigue, myalgia, and arthralgia. Laboratory tests showed characteristic thrombocytopenia, leukopenia, and pathological values of AST and ALT. The clinical picture is characterized by symptoms of persisting fatigue and exhaustion, even after the fever has subsided.- - - - - - - - - - ranking = 1.8keywords = fever (Clic here for more details about this article) |
16/82. Dengue fever associated with a haematoma of the rectus abdominis muscle.We describe a patient with dengue fever with a haematoma of the rectus abdominis muscle, due to a tear in the inferior epigastric artery following episodes of retching. From the literature reviewed, we noted that there are no previous reports of dengue fever associated with muscle haematomas.- - - - - - - - - - ranking = 1.2keywords = fever (Clic here for more details about this article) |
17/82. Virologic and serologic surveillance for dengue fever in Jeddah, saudi arabia, 1994-1999.Dengue fever infection was first documented in Jeddah, saudi arabia, by virus isolation of dengue type 2 virus in 1994 at the virology laboratory of Dr. Soliman Fakeeh Hospital. dengue virus surveillance was established after that time. blood samples were collected from 985 patients (710 male patients and 275 female patients) with suspected cases of dengue from February 1994 to December 1999. dengue virus isolates were obtained in 207 patients (21%; 162 male patients and 45 female patients). Dengue type 2 was the predominant serotype (138 of 207 isolates, 66.7%), followed by dengue type 1 with (56 of 207 isolates, 27%) and dengue type 3 (13 of 207 isolates, 6.3%). The largest number of isolates (186 of 207 isolates, 90%) was in 1994, a year during which there was a dengue epidemic. In the next 5 years, 1995-1999, only 21 isolates (10%) were isolated. immunoglobulin m capture enzyme-linked immunosorbent assay was positive in 160 acute samples; 52 of them were from virus culture-positive cases and 108 (11%) from culture-negative cases. The total number of cases diagnosed by both methods was 315 (32%). The prevalence of dengue immunoglobulin g antibodies, as assessed on the basis of immunofluorescent assay, hemagglutination inhibition titers > or = 1/20, or both, in the acute samples was 314 (32%) of 985, indicating past flavivirus infection. Two patients died, one man with dengue hemorrhagic fever and one woman with dengue shock syndrome. Both fatal dengue cases were due to infection with type 2 virus. All other cases were simple dengue fever. To our knowledge, this is the first report confirming the circulation of 3 dengue serotypes in Jeddah.- - - - - - - - - - ranking = 1.4keywords = fever (Clic here for more details about this article) |
18/82. Perinatal dengue infection.We report a case of vertical transmission of dengue infection in an infant. The mother's was a term pregnancy with a history of chronic hypertension. She presented with high fever of 3 days duration 5 days prior to delivery. Her initial complete blood count showed platelet count of 64,000/mm3. Dengue hemorrhagic fever was diagnosed 2 days later and symptomatic treatment was given. During labor her platelets dropped to 11,000/mm3 and platelet concentrate was given. cesarean section was performed due to prolonged second stage of labor. Her infant was normal at birth except for petechiae on the left thigh. The child's platelet count was 34,000/mm3 and low grade fever was detected on the first day. Clinical sepsis was suspected and antibiotic treatment was started and continued for 4 days until all the cultures came back as negative. Both mother and her baby made an uneventful recovery and were discharged 6 days after delivery with normal platelet counts. Maternal blood was positive for IgM antibody to dengue virus. Both cord blood and the baby's blood were positive for dengue virus serotype 2 by PCR.- - - - - - - - - - ranking = 0.6keywords = fever (Clic here for more details about this article) |
19/82. Acute disseminated encephalomyelitis following dengue fever.A58-year-old man suffered from acute disseminated encephalomyelitis (ADEM) after dengue fever. ADEM has not been described as the cause of neurological complications in dengue fever. However, the increasing use of magnetic resonance imaging in endemic areas may help to identify ADEM as being responsible for neurological complications in dengue fever.- - - - - - - - - - ranking = 1.4keywords = fever (Clic here for more details about this article) |
20/82. Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis).A dengue fever case is described in a 58-year-old male patient with febrile illness and thrombocytopenia complicated by neurological involvement characterized by transverse myelitis followed by weakness of both legs and flaccid paralysis. muscle strength was much diminished and bilateral areflexia was observed. Dengue 2 (DEN-2) virus was isolated and the patient sero-converted by hemagglutination-inhibition and IgM-ELISA tests. The RT-PCR test was positive to DEN-2 in acute phase serum and culture supernatant, but negative in the cerebrospinal fluid. After three weeks of hospitalization the patient was discharged. No other infectious agent was detected in the blood and cerebrospinal fluid samples. The patient had full recovery from paralysis six months after the onset of DEN-2 infection.- - - - - - - - - - ranking = 0.2keywords = fever (Clic here for more details about this article) |
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