1/6. Persistent cellulitis in a patient receiving renal dialysis.cryptococcus neoformans, an opportunistic fungus, may cause cutaneous disease by dissemination from primary lung infection or, more rarely, by direct cutaneous inoculation. cellulitis in an immunocompromised host who does not respond to conventional antibacterial therapy should alert the physician to consider other diagnoses, including cryptococcal skin infection.- - - - - - - - - - ranking = 1keywords = physician (Clic here for more details about this article) |
2/6. Cryptococcal necrotizing fasciitis with multiple sites of involvement in the lower extremities.BACKGROUND: Cryptococcal necrotizing fasciitis that is localized to the lower extremities is very rare. OBJECTIVE: We describe a case of a renal transplant recipient who presented with necrotizing fasciitis of the legs caused by cryptococcus neoformans, a fungus that is rarely associated with this disease. methods: This is a case report with literature review. RESULTS: The patient was hospitalized, and the site of infection was debrided to the level of the periosteum. Cultures and histopathologic examination of biopsy material revealed an invasive deep-seated infection with a fungal organism that was consistent with C. neoformans. After 21 days on parenteral amphotericin b (Ambisome; Er-Kim Pharmaceuticals) treatment, the patient was switched to oral itraconazole (Itraspor; Janssen-Cilag Pharmaceuticals) 200 mg/day. He was discharged after 30 days of hospitalization with his wounds completely healed. He continued on oral fluconazole for a total course of 6 weeks. CONCLUSION: Systemic fungal infections continue to be an important cause of morbidity and mortality in transplant recipients. The insidious nature and atypical manifestations of these infections often delay diagnosis and therapy. In immunosuppressed patients, persistent fever that does not respond to antibacterial therapy should alert the physician to the possibility of fungal infection.- - - - - - - - - - ranking = 1keywords = physician (Clic here for more details about this article) |
3/6. Multifocal choroiditis in disseminated cryptococcus neoformans infection.PURPOSE: To report an uncommon case of multifocal choroiditis as the result of disseminated cryptococcus neoformans infection in a patient who is hiv-positive. DESIGN: Interventional case report. methods: A 27-year-old hiv-positive woman with fever, headache, and vomiting was examined. Lumbar puncture was performed and revealed C neoformans infection. Her condition evolved with sudden bilateral blindness and deafness. Ophthalmologic examination revealed multiple yellowish choroidal lesions in the posterior pole of both eyes. RESULTS: Postmortem examination showed disseminated C neoformans infection. Histologic examination of the eyes confirmed the presence of C neoformans in the choroiditis. CONCLUSION: Multifocal choroiditis in C neoformans infection is a rare ophthalmic manifestation. The recognition of this condition by ophthalmologists can help physicians to diagnose a disseminated and fatal disease.- - - - - - - - - - ranking = 1keywords = physician (Clic here for more details about this article) |
4/6. Cryptococcal anal ulceration in a patient with AIDS.We report the case of an African patient with acquired immune deficiency syndrome (AIDS) who had a chronic cryptococcal rectal abscess with anal fistula and a disseminated neurologic and bony fungal disease, associated with pulmonary infiltration due to pneumocystis carinii. The anal lesion was surgically excised because of failure of the medical treatment. Although clinical intestinal cryptococcal involvement is quite rare, the experience here recorded should draw physicians' attention to the possibility of an insidious disseminated disease in AIDS patients.- - - - - - - - - - ranking = 1keywords = physician (Clic here for more details about this article) |
5/6. Mania with cryptococcal meningitis in two AIDS patients.Two AIDS patients with mania were found to have cryptococcal meningitis. In patients with AIDS or aids-related complex, physicians must thoroughly investigate the possibility of an organically based psychiatric syndrome.- - - - - - - - - - ranking = 1keywords = physician (Clic here for more details about this article) |
6/6. Cryptococcal pneumonia: a fulminant presentation.A 32-year-old presented with fulminant, bilateral airspace pneumonia due to cryptococcus neoformans while under cytotoxic therapy for advanced Hodgkin's disease. We alert physicians to this rapidly progressive form of cryptococcosis which has been poorly described previously and which may closely mimic bacterial pneumonia.- - - - - - - - - - ranking = 1keywords = physician (Clic here for more details about this article) |