Cases reported "Candidiasis, Oral"

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1/15. fluconazole for postpartum candidal mastitis and infant thrush.

    This case report illustrates the difficulties inherent in treating candidal mastitis in lactating women and concurrent thrush in the breastfeeding baby. This mother's candidiasis vacillated from topical to ductal, depending on which medications were being used over the course of several months. Her baby's oral thrush was unique in that there were never any white plaques visible on his oral mucosa. Ultimately, both mother and child were treated simultaneously with oral fluconazole, with a relief of symptoms in both individuals.
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keywords = candida
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2/15. Oral candidosis in non-Hodgkin's lymphoma: a case report.

    Though oral candidosis is an opportunistic fungal infection that commonly affects immunocompromised patients, little is known of its occurrence as a complication of Non-Hodgkin's lymphoma. This paper reports a case of oral candidosis in a 20-year-old Indonesian woman with this lymphoproliferative disease. She presented with acute pseudomembranous candidosis on the dorsum and lateral borders of the tongue, bilateral angular cheilitis and cheilocandidosis. The latter is a rare clinical variant of oral candidosis, and the lesions affecting the vermilion borders presented as an admixture of superficial erosions, ulcers and white plaques. Clinical findings were confirmed with oral smears and swabs that demonstrated the presence of hyphae, pseudohyphae and blastospores, and colonies identified as candida albicans. A culture from a saline rinse was also positive for multiple candidal colonies. lip and oral lesions were managed with nystatin. The lesions regressed with subsequent crusting on the lips, and overall reduction in oral thrush. As Non-Hodgkin's lymphoma is a neoplastic disease that produces a chronic immunosuppressive state, management of its oral complications, including those due to oral candidosis, is considered a long-term indication.
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ranking = 0.2
keywords = candida
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3/15. Chronic mucocutaneous candidiasis: a case report.

    Chronic mucocutaneous candidiasis is a immuno deficiency disorder primarily due to T cell dysfunction characterized by persistent candidal infection of mucous membrane, skin, scalp and nails. Chronic mucous membrane candidiasis has an onset in infancy or childhood; the primary affected site is the oral cavity; however, lesions may occur on trunk, hands, feet and scalp. This paper describes a 12-year-old girl with candidial infection of the oral mucosa and extra oral involvement of fingers, nails, toes and intertragus area.
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ranking = 0.2
keywords = candida
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4/15. Candida laryngotracheitis: a complication of combined steroid and antibiotic usage in croup.

    The use of corticosteroids to reduce the morbidity associated with laryngotracheobronchitis (croup) has been a controversial issue for many years. Recent literature, however, does support a decreased morbidity and increased clinical response when short-term steroids are used. As a prophylactic measure against bacterial superinfection, antibiotics are commonly utilized in the treatment of croup. We present the case of an otherwise healthy infant with severe croup who was hospitalized and treated with both steroids and antibiotics. A relapse in her symptoms led to the diagnosis of candida laryngotracheitis. We recommend close monitoring of patients with croup treated aggressively with steroids and antibiotics. Steroid use should be limited to 24 h with antibiotics reserved for patients with signs of bacterial infection.
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ranking = 0.2
keywords = candida
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5/15. dna identification of the pathogen of candidal aspiration pneumonia induced in the course of oral cancer therapy.

    Aspiration of oropharyngeal bacteria and fungi is occasionally suspected in patients with pneumonia. A patient with oral carcinoma underwent chemoradioimmunotherapy and, about 4 weeks from the start of the therapy, the patient suffered from severe oral mucositis induced by chemoradiotherapy, and candidal pneumonia was subsequently induced. The candidal pneumonia was insufficiently improved by potent antifungal drugs, taking a lethal course. Randomly amplified polymorphic dna analysis and dna sequence examination of strains isolated from the oral cavity 1 week before the onset of pneumonia and autopsied lung revealed the identity of both strains as candida albicans, and the dna analysis supported aspiration of oral Candida. These results indicate that the pathogen of the pneumonia, C. albicans, was aspirated from the oral cavity and that oral Candida is easily aspirated and becomes the pathogen of pneumonia.
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ranking = 1.2
keywords = candida
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6/15. Treatment of candidal leukoplakia with fluconazole.

    A case of candidal leukoplakia (chronic hyperplastic candidosis) treated with the systemic antifungal agent, fluconazole, is reported. Dramatic clinical and histopathological resolution of the condition occurred following 11 days of drug therapy.
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ranking = 1
keywords = candida
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7/15. The relationship of oral candida tropicalis infection to systemic candidiasis in a patient with leukemia.

    Oropharyngeal candidiasis is an extremely common complication in patients receiving chemotherapy for leukemia. candida tropicalis appears to be the major infectious agent when these patients develop candidemia. In this article, a case of C tropicalis fungemia with oropharyngeal manifestations is presented. The relationship of oropharyngeal candidiasis to oral candidal infection is discussed.
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ranking = 0.2
keywords = candida
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8/15. Refractory oral candidiasis. Report of a case.

    A 55-year-old male patient with no significant medical history or systemic physical findings was found, on routine dental examination, to have an oral candida albicans infection. The condition failed to clear completely after 21 days of nystatin therapy. A 5-day course of clotrimazole was then initiated. Complete clearing of all signs of candida infection occurred in 48 hours, but the infection recurred by the twentieth day of follow-up. A 14-day regimen was then prescribed. Again, the condition cleared in 48 hours, and at the 6-month follow-up all signs of candida involvement, including cultures and smears, remained negative. As no reports of the use of clotrimazole vaginal tablets in oral candidiasis clinically refractory to nystatin therapy were found in the literature of the last 11 years, it was thought that this case was of significant interest.
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ranking = 0.4
keywords = candida
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9/15. Late onset chronic mucocutaneous candidiasis with lymphoma and specific serum inhibitory factor.

    A patient with late onset chronic mucocutaneous candidiasis developed lymphocytic lymphoma. A specific inhibitor of in vitro lymphoproliferative responses to candidal antigen was detected in her serum which persisted following clinical remission of candidiasis after combined amphotericin-B and 5-Fluorocystosine therapy. It is unclear whether the combined therapy was exclusively anticandidal, nonspecific immunostimulant or cytotoxic affecting the underlying incipient lymphoma.
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ranking = 0.4
keywords = candida
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10/15. nystatin-resistance of candida albicans isolates from two cases of oral candidiasis.

    Two cases of oral candidiasis are described which failed to respond to nystatin therapy when used in combination with triamcinolone acetonide. The isolates of C. albicans obtained from the patients after treatment showed high in vitro resistance to nystatin when tested in combination with triamcinolone acetonide. triamcinolone acetonide was detected in the saliva of both patients after treatment. Addition of this saliva to the isolates of C. albicans obtained after treatment was found to confer nystatin resistance. Both patients were treated with miconazole nitrate and a mycological and clinical cure was obtained in one of the cases.
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ranking = 0.8
keywords = candida
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